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Prescription requiredTorrent Pharmaceuticals LtdNEURO CNS

Zisper Plus

Risperidone (3mg) + Trihexyphenidyl (2mg)

Currently out of stock

Same composition, in stock now. Check with your doctor or pharmacist before you switch.

  • Don Plus Tablet₹78View
  • Risdone Plus₹92View

Zisper Plus is used for treatment of Schizophrenia.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Risperidone (3mg) + Trihexyphenidyl (2mg)
Available variants: NA 10`S
Best price: ₹61
MRP: ₹65
Prescription: Required
Manufacturer: TORRENT PHARMACEUTICALS

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Zisper Plus

Zisper Plus contains Risperidone (3mg) + Trihexyphenidyl (2mg). It belongs to the Antipsychotic and Anti-dementia / anti-parkinsonian agent class of medicines.

Uses of Zisper Plus

Treatment of Schizophrenia

Key benefits

  • In Treatment of Schizophrenia Schizophrenia is a mental disorder in which a person’s thinking ability
  • feelings
  • and behavior become abnormal. Zisper Plus Tablet helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts and behavior and enhances the quality of life. Do not stop taking it unless advised by the doctor. It can take several weeks for your symptoms to improve
  • so keep using the medicine even if you do not think it is working.

How Zisper Plus works

Zisper Plus Tablet is a combination of two medicines: Risperidone and Trihexyphenidyl. Risperidone is an atypical antipsychotic that works by balancing the levels of chemical messengers (dopamine and serotonin) to improve mood, thoughts, and behavior. Trihexyphenidyl is an anticholinergic that works on the nervous system and corrects some of the chemical imbalances that cause Parkinson's disease and certain side effects occurring during antipsychotic treatment.

How to take Zisper Plus

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zisper Plus Tablet may be taken with or without food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Zisper Plus Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause deep drowsiness, a severe fall in blood pressure, abnormal movements and heart rhythm disturbance. It can cause severe confusion, abnormal movements, a very slow pulse and collapse. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Zisper Plus

Most side effects of Zisper Plus are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Zisper Plus

PregnancyPregnancy UNSAFE
BreastfeedingBreast feeding CONSULT YOUR DOCTOR
AlcoholAlcohol UNSAFE
DrivingDriving UNSAFE
KidneyKidney CAUTION
LiverLiver CAUTION
Habit formingNo

Warnings and precautions

Report any tremor, stiffness, restlessness or uncontrollable movements of the face, tongue or limbs to your doctor promptly — these can become persistent if not addressed. Seek emergency care for high fever with severe muscle stiffness, confusion and sweating. This is rare but life-threatening. These medicines can raise blood sugar, cholesterol and weight. Your doctor will monitor them — keep those appointments. Never stop suddenly; your doctor will reduce the dose gradually. Take care in hot weather — this group affects how your body regulates temperature. Never stop a Parkinson's medicine suddenly — this can cause a severe and dangerous deterioration. Dose timing matters a great deal in Parkinson's disease. Take it at exactly the times prescribed. Report sudden daytime sleep attacks, hallucinations, or new gambling, spending or other impulsive behaviour — these are recognised effects and the dose may need review. Rise slowly from sitting or lying; a drop in blood pressure on standing is common.

Do not take Zisper Plus if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Your doctor will assess suitability if you have heart disease, Parkinson's disease or dementia. Your doctor will assess suitability if you have heart, eye or psychiatric conditions.

Interactions with other medicines

Alcohol and sedatives add to the drowsiness. Tell your doctor about any medicine that affects heart rhythm. Anti-emetics such as metoclopramide and some antipsychotics can worsen Parkinson's symptoms. High-protein meals can reduce the absorption of levodopa — ask your doctor about timing.

How to store Zisper Plus

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Zisper Plus

Use caution while driving or doing anything that requires concentration, as Zisper Plus Tablet can cause dizziness and sleepiness. Avoid consuming alcohol while taking this medication, as it may lower its efficacy. It can cause dry mouth. Maintain good oral hygiene, drink water, chew sugarless gum, or suck on hard candy for the dry mouth. It may cause an increase in weight, blood sugar, cholesterol, and triglycerides (fat). Eat healthy, exercise, and monitor your levels regularly. Inform your doctor if you have glaucoma or trouble passing urine. Do not stop taking Zisper Plus Tablet without talking to your doctor first, as it may cause a worsening of symptoms.

Manufacturer and class

Manufacturer:
TORRENT PHARMACEUTICALS
Therapeutic class:
NEURO CNS
Drug class:
Antipsychotic and Anti-dementia / anti-parkinsonian agent

Substitutes for Zisper Plus

Medicines with the same active ingredient (Risperidone (3mg) + Trihexyphenidyl (2mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Zisper Plus
Don Plus TabletCRESCENT FORUMULATIONS PVT LTDtablet · 10`S₹7827% more
Risdone PlusIntas Pharmaceuticals Ltd10`S₹9249% more
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Zisper Plus FAQs

What is Zisper Plus used for?
Zisper Plus is commonly used for Treatment of Schizophrenia. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Zisper Plus?
Zisper Plus contains Risperidone (3mg) + Trihexyphenidyl (2mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Zisper Plus?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Zisper Plus work?
Zisper Plus Tablet is a combination of two medicines: Risperidone and Trihexyphenidyl.
Is Zisper Plus a prescription medicine?
Yes. Zisper Plus is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Zisper Plus?
The side effects reported most often with Zisper Plus are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Zisper Plus be taken during pregnancy?
Pregnancy UNSAFE Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Zisper Plus.
Can I drink alcohol while taking Zisper Plus?
Alcohol UNSAFE
What if I miss a dose of Zisper Plus?
If you miss a dose of Zisper Plus Tablet, take it as soon as possible.
Is Zisper Plus habit forming?
No. Zisper Plus is not known to be habit forming when taken as prescribed.
How much does Zisper Plus cost on PingMeDoc Pharmacy?
Zisper Plus starts at ₹61 (MRP ₹65) on PingMeDoc Pharmacy. Available in NA 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Zisper Plus?
Zisper Plus is manufactured by TORRENT PHARMACEUTICALS. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Zisper Plus delivered?
Zisper Plus is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Zisper Plus, Quick facts

Salt
Risperidone (3mg) + Trihexyphenidyl (2mg)
Best price
₹61
MRP
₹65
Prescription
Required (Rx)
Schedule
Schedule H
Brand
Torrent Pharmaceuticals Ltd
Manufacturer
TORRENT PHARMACEUTICALS
Therapeutic class
NEURO CNS
Drug class
Antipsychotic and Anti-dementia / anti-parkinsonian agent
Habit forming
No
Variants
NA 10`S
Delivery
Standard across India

References

The information on Zisper Plus is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Zisper Plus.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.