
Actibile 150MG Tab
Zydus Healthcare Pharma - Tablet - 150 mg - 10 S
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Prescription required
Aceclofenac (100mg) + Paracetamol (325mg) + Serratiopeptidase (15mg)
Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.
This medicine needs a prescription.
You can pay now and add the prescription afterwards. We pack your order only after a pharmacist verifies it.
A doctor decides whether a prescription can be issued. If it is not issued, the prescription items in your order are cancelled and refunded. You choose this at checkout.
Zynac SP Tablet is used for relief of pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, back pain, sprain/strain, dental pain, post-operative pain, and other musculoskeletal inflammatory conditions.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Medicines with the same active ingredient and strength as Zynac SP Tablet.
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Zynac SP Tablet
tablet - 100mg + 325mg + 15mg - 10 S
₹127
₹12.66 per tablet
RISNIK LIFE SCIENCE PVT LTD · tablet - 100mg + 325mg + 15mg - 10 S · Rx
₹52
₹5.23 per tablet
XYRIS LIFE SCIENCES PVT LTD · tablet - 100mg + 325mg + 15mg - 10 S · Rx
₹57
₹5.70 per tablet
BIOCEUTICS · tablet - 100mg + 325mg + 15mg - 10 S · Rx
₹71
₹7.13 per tablet
A substitute contains the same active ingredient (salt), in the same strength, as Zynac SP Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.
All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.
Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.
Zynac SP Tablet contains Aceclofenac (100mg) + Paracetamol (325mg) + Serratiopeptidase (15mg). It belongs to the NSAID (Aceclofenac) + Analgesic/Antipyretic (Paracetamol) + Proteolytic enzyme (Serratiopeptidase) class of medicines.
Aceclofenac reduces pain and inflammation by inhibiting cyclo‑oxygenase (COX) enzymes and lowering prostaglandin production. Paracetamol provides analgesic and antipyretic action by acting centrally. Serratiopeptidase is a proteolytic enzyme that helps reduce tissue swelling and inflammation.
Tablet for oral use. Take as prescribed by a doctor, preferably after food with water. Do not crush/chew. Avoid taking other paracetamol-containing products simultaneously unless advised.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Zynac SP 100mg/325mg/15mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
An overdose of this medicine can cause stomach bleeding, kidney failure, drowsiness and fits. It can cause severe and sometimes fatal liver damage, often with no symptoms at all for the first day. It can seriously suppress the bone marrow and damage the liver. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Zynac SP are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Not recommended (especially in 3rd trimester); consult doctor |
|---|---|
| Breastfeeding | Breast feeding CONSULT YOUR DOCTOR |
| Alcohol | Avoid |
| Driving | Driving UNSAFE |
| Kidney | Kidney CAUTION |
| Liver | Liver CAUTION |
| Habit forming | No |
Use with caution in patients with stomach/duodenal ulcer, gastrointestinal bleeding, asthma, kidney disease, liver disease, heart disease, hypertension, or bleeding disorders. NSAIDs may increase risk of GI bleeding and cardiovascular events; seek medical help for black stools, vomiting blood, chest pain, or severe breathlessness. Do not exceed recommended dose or duration; overdose of paracetamol can cause severe liver damage. Avoid in known hypersensitivity to NSAIDs/paracetamol/serratiopeptidase.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy. Not for people with severe liver disease, except under medical supervision. Not for people with an active serious infection, or with severe liver or bone-marrow disease. Several of these medicines must not be used in pregnancy.
Alcohol, anticoagulants/antiplatelets (warfarin, aspirin, clopidogrel), other NSAIDs, corticosteroids, SSRIs/SNRIs, antihypertensives (ACE inhibitors/ARBs, diuretics), lithium, methotrexate, cyclosporine/tacrolimus, digoxin, other paracetamol-containing medicines
Store below 25°C in a cool, dry place away from light and moisture. Keep out of reach of children.
Do not take Zynac SP 100mg/325mg/15mg Tablet with other medicines containing paracetamol (acetaminophen), such as some cold or fever medicines, unless advised by your doctor. Avoid combining Zynac SP 100mg/325mg/15mg Tablet with other NSAID painkillers unless your doctor recommends it. Avoid alcohol while taking Zynac SP 100mg/325mg/15mg Tablet, as it may increase stomach irritation and the risk of liver damage. Zynac SP 100mg/325mg/15mg Tablet may cause dizziness or drowsiness, so avoid driving or operating machinery until you know how it affects you. Stay well hydrated while using Zynac SP 100mg/325mg/15mg Tablet, as dehydration may increase the risk of kidney-related side effects. Inform your doctor if you have kidney disease, heart disease, asthma, stomach ulcers, or uncontrolled high blood pressure before taking Zynac SP 100mg/325mg/15mg Tablet. Seek urgent medical attention if you notice black stools, vomiting blood, severe stomach pain, or unusual bruising. Stop taking Zynac SP 100mg/325mg/15mg Tablet and seek medical help if you develop rash, swelling of the face, or breathing difficulty. Use Zynac SP 100mg/325mg/15mg Tablet only for the duration prescribed, and consult your doctor if pain, swelling, or fever persists despite treatment. Tell your doctor if you are taking blood thinners, steroids, or certain antidepressants that may increase bleeding risk.
Medicines with the same active ingredient (Aceclofenac (100mg) + Paracetamol (325mg) + Serratiopeptidase (15mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Zynac SP Tablet |
|---|---|---|---|
| Velocist-P TabletRISNIK LIFE SCIENCE PVT LTD | tablet · 10`S | ₹52 | 59% cheaper |
| Xypace TabletXYRIS LIFE SCIENCES PVT LTD | tablet · 10`S | ₹57 | 55% cheaper |
| Aserra P TabletBIOCEUTICS | tablet · 10`S | ₹71 | 44% cheaper |
| Flexace-SP TabletAMNEAN THERAPEUTICS | tablet · 10`S | ₹79 | 37% cheaper |
| Ark SP TabletAPEX LABORATORIES LTD` | tablet · 10`S | ₹88 | 31% cheaper |
| Neorelax SP TabletMEYER ORGANICS PVT LTD | tablet · 10`S | ₹102 | 20% cheaper |
| Torpedo SP TabletWALFS PHARMA | tablet · 10`S | ₹103 | 19% cheaper |
| Ashycloflam SP Tablet A/A | 1X10 | ₹104 | 18% cheaper |
| Ebility Asp TabletAbbott Healthcare Pvt Ltd | tablet · 10`S | ₹107 | 16% cheaper |
| Acemiz S Tablet | 1X10 | ₹121 | 5% cheaper |
| Megaceclo SP Tablet | 1X10 | ₹123 | 3% cheaper |
| Zerodol SP TabletIPCA LABORATORIES LTD` | tablet · 10 Tablet | ₹126 | 1% cheaper |

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The information on Zynac SP Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.