Apidra Solostar

Insulin Glulisine (100IU/ml)

Treatment of diabetes mellitus (Type 1 and Type 2) to improve glycaemic control; used as prandial (mealtime) insulin as part of a basal-bolus regimen.

Insulin glulisine is a rapid-acting insulin analogue that lowers blood glucose by increasing glucose uptake in muscle and fat and reducing hepatic glucose production. It also inhibits lipolysis and proteolysis and promotes protein synthesis.

Subcutaneous injection using the prefilled pen. Inject within 15 minutes before a meal or within 20 minutes after starting a meal, as prescribed. Rotate injection sites (abdomen, thigh, upper arm); do not inject into veins or muscles unless specifically instructed. Do not share the pen; use a new needle for each injection.

Hypoglycaemia, injection site reactions (redness/pain/swelling/itching), lipodystrophy at injection site, weight gain, allergic reactions, oedema

Risk of severe hypoglycaemia—monitor blood glucose regularly and carry fast-acting sugar. Dose adjustments may be needed with changes in diet/exercise, illness, stress, or switching insulin. Use caution in renal or hepatic impairment (may need lower dose). Do not use if solution is cloudy/colored or pen is damaged; do not freeze. Allergy to insulin glulisine/excipients is a contraindication. Use caution while driving/operating machinery due to hypoglycaemia risk.

Other antidiabetic drugs may increase hypoglycaemia risk; beta-blockers may mask hypoglycaemia symptoms; corticosteroids, thiazide diuretics, thyroid hormones, sympathomimetics and some antipsychotics may raise glucose and increase insulin needs; ACE inhibitors, salicylates and alcohol may increase hypoglycaemia risk.

Unopened pens: store refrigerated at 2–8°C; do not freeze; keep away from freezer compartment and protect from light. In-use pen: keep at room temperature (generally below 25°C) as per label and use within the recommended in-use period; keep cap on; do not refrigerate in-use pen if label advises otherwise.

Humalog KwikPen (Insulin lispro), NovoRapid FlexPen (Insulin aspart), Fiasp FlexTouch (Faster insulin aspart), Humalog Cartridge (Insulin lispro), NovoRapid Penfill (Insulin aspart)