Toujeo 300U/Ml Cartridge Injection

For subcutaneous use only. Inject once daily at the same time each day (as advised by the doctor) into abdomen, thigh or upper arm; rotate injection sites. Do not inject into a vein or muscle and do not mix/dilute with other insulins. Follow prescribed dose and titration based on blood glucose; use the compatible insulin pen/device for Toujeo cartridges as instructed.

Insulin glargine is a long-acting insulin analogue. After subcutaneous injection, it forms a depot in the tissue and is slowly released, providing a steady basal insulin level that lowers blood glucose by increasing peripheral glucose uptake and reducing hepatic glucose production.

Risk of hypoglycaemia—monitor blood glucose regularly and carry fast-acting sugar. Use caution in renal/hepatic impairment, elderly, irregular meals, increased exercise, or alcohol use. Do not use during episodes of hypoglycaemia. Not for treatment of diabetic ketoacidosis (use short-acting insulin). Switching from other insulins should be done under medical supervision (dose differences between U-100 and U-300). Seek urgent care for severe allergic reaction. Use proper injection technique and site rotation to reduce lipodystrophy.

Other antidiabetic drugs (additive hypoglycaemia),ACE inhibitors/ARBs (may increase hypoglycaemia risk),beta-blockers (may mask hypoglycaemia symptoms),corticosteroids/thyroid hormones/sympathomimetics (may increase blood glucose),thiazide diuretics (may increase blood glucose),alcohol (can increase risk of hypoglycaemia),pioglitazone/other TZDs (risk of fluid retention/heart failure when used with insulin)

Store unopened cartridges refrigerated at 2–8°C; do not freeze and keep away from freezer compartment. Protect from light; keep in outer carton. After first use, keep at room temperature (do not refrigerate) below 30°C, away from heat/light, and use within the period stated on the label/device instructions; do not use if solution is cloudy or contains particles.

Lantus 100IU/ml Cartridge,Abasaglar 100IU/ml Cartridge,Basaglar 100IU/ml Cartridge,Semyglee (insulin glargine) 100IU/ml Cartridge,Tresiba (insulin degludec) Penfill