Distributor inventory | Tablet

Type 2 diabetes mellitus: to improve glycaemic control in adults when diet and exercise alone are not sufficient; can be used with other antidiabetic medicines as advised by doctor.

Empagliflozin is an SGLT2 inhibitor that lowers blood sugar by increasing urinary glucose excretion through the kidneys. Linagliptin is a DPP-4 inhibitor that increases incretin levels, enhancing insulin release and reducing glucagon secretion in a glucose-dependent manner.

Take orally as prescribed, usually once daily at the same time each day, with or without food. Swallow whole with water; do not crush/chew. Monitor blood glucose regularly and follow diet/exercise advice.

Increased urination,genital fungal infection,urinary tract infection,thirst,low blood sugar (especially with insulin/sulfonylureas),nasopharyngitis,headache,nausea

Not for type 1 diabetes or diabetic ketoacidosis. Risk of dehydration/low blood pressure especially in elderly, on diuretics, or with low fluid intake; maintain hydration. Empagliflozin may increase risk of genital infections and UTIs; seek care for fever, pain/burning urination. Monitor kidney function before and during treatment; use with caution/avoid in severe renal impairment as advised by doctor. Stop and seek medical help if symptoms of pancreatitis occur (severe abdominal pain) or severe allergic reactions. Withhold before major surgery or during acute illness/fasting as SGLT2 inhibitors can rarely cause euglycaemic ketoacidosis.

Insulin and sulfonylureas (increased hypoglycaemia risk),diuretics (increased dehydration/hypotension),other antidiabetics,rifampicin/carbamazepine/phenytoin/phenobarbital (may reduce linagliptin effect),strong P-gp/CYP3A4 inducers,alcohol (may increase hypoglycaemia/dehydration risk)

Store below 25°C in a cool, dry place away from moisture and direct light. Keep in original pack and out of reach of children.

Glyxambi 25/5 Tablet,Jardiance Duo 25/5 Tablet,Empagliflozin 25 mg + Linagliptin 5 mg Tablet (generic),Glyxambi 10/5 Tablet (different strength),Jardiance 25 mg + Trajenta 5 mg (separate tablets)