Dolonex IM Injection

Piroxicam 20 mg/2 mL (as piroxicam) injection

Relief of pain and inflammation in acute musculoskeletal conditions, acute gout, postoperative pain, and flare-ups of rheumatoid arthritis or osteoarthritis when oral therapy is not suitable.

Piroxicam is an NSAID that inhibits cyclo-oxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthesis. This lowers inflammation, pain, and swelling.

For intramuscular (IM) use only; administer deep IM by a healthcare professional. Dose and duration as prescribed; usually used short term and may be switched to oral therapy when appropriate. Do not inject intravenously or subcutaneously.

Injection site pain, nausea, vomiting, abdominal pain, heartburn, diarrhea, dizziness, headache, edema

Prescription-only (Schedule H). NSAIDs may increase risk of stomach/intestinal ulcer or bleeding (higher in elderly, history of ulcer, with alcohol, steroids, anticoagulants). May increase risk of heart attack or stroke, especially with higher doses/long use. Use with caution in asthma, hypertension, heart failure, kidney or liver disease, dehydration. Stop and seek care if black stools, vomiting blood, severe abdominal pain, rash/blistering, facial swelling, breathing difficulty. Avoid in active peptic ulcer/bleeding and severe heart, kidney or liver impairment unless advised by doctor.

Anticoagulants/antiplatelets (warfarin, aspirin, clopidogrel), other NSAIDs, corticosteroids, SSRIs/SNRIs, antihypertensives (ACE inhibitors/ARBs, diuretics), lithium, methotrexate, cyclosporine/tacrolimus, digoxin

Store below 25°C. Protect from light. Do not freeze. Keep out of reach of children.

Pirox 20 mg Injection, Pirocam 20 mg Injection, Piroxid 20 mg Injection, Piroxin 20 mg Injection, Piroxicam 20 mg/2 mL Injection (generic)