Metolar XR 12.5

Metoprolol succinate extended-release 12.5 mg (per tablet)

Hypertension (high blood pressure), angina (chest pain), chronic stable heart failure (as adjunct therapy), rate control in certain tachyarrhythmias; may be used for secondary prevention after myocardial infarction as per physician advice

Metoprolol is a cardioselective beta-1 adrenergic blocker. It reduces heart rate and contractility, lowering blood pressure and myocardial oxygen demand. The XR formulation releases medicine slowly to provide 24-hour control.

Take by mouth once daily at the same time each day, with or without food. Swallow the extended-release tablet whole; do not crush/chew/split unless advised. Dose is individualized; do not stop suddenly without medical supervision.

Tiredness, dizziness, slow heart rate (bradycardia), low blood pressure, headache, nausea, cold hands/feet, sleep disturbances

Do not stop abruptly (may worsen angina/trigger heart attack). Use with caution in asthma/COPD (may cause bronchospasm), diabetes (may mask hypoglycaemia symptoms), thyroid disorders, peripheral vascular disease, liver impairment, and in patients with low heart rate/heart block. Contraindicated in severe bradycardia, second/third-degree AV block, cardiogenic shock, and acute decompensated heart failure unless directed by a specialist. Monitor pulse and blood pressure regularly.

Other antihypertensives (additive hypotension), calcium channel blockers like verapamil/diltiazem (risk of bradycardia/heart block), antiarrhythmics (e.g., amiodarone), digoxin, clonidine (rebound hypertension if stopped improperly), NSAIDs (may reduce antihypertensive effect), CYP2D6 inhibitors such as fluoxetine/paroxetine/quinidine (may increase metoprolol levels), insulin/oral antidiabetics (masked hypoglycaemia)

Store at room temperature (below 25°C), protected from moisture and light. Keep in original blister pack and out of reach of children.

Met XL 12.5 Tablet ER, Betaloc ZOK 12.5 Tablet ER, Starpress XL 12.5 Tablet ER, Prolol XL 12.5 Tablet ER, Metoprolol Succinate ER 12.5 mg (generic)