Thyroup 25

Thyroxine (25mcg)

Treatment of hypothyroidism (underactive thyroid), thyroid hormone replacement after thyroidectomy or radioactive iodine therapy, management of goitre due to thyroid hormone deficiency

Levothyroxine is a synthetic form of thyroxine (T4), a natural thyroid hormone. It is converted to triiodothyronine (T3) in the body and restores normal thyroid hormone levels, helping regulate metabolism, energy and growth.

Tablet for oral use. Take once daily on an empty stomach, preferably in the morning 30–60 minutes before breakfast, with water. Take at the same time each day; avoid taking with calcium/iron/antacids—keep a 4-hour gap. Dose is individualized based on TSH and clinical response; do not stop abruptly without medical advice.

Palpitations,fast heartbeat,anxiety,irritability,tremor,headache,insomnia,heat intolerance,increased sweating,weight loss,diarrhoea,nausea,menstrual irregularities

Use only under medical supervision with periodic TSH monitoring. Overdose/over-replacement may cause symptoms of hyperthyroidism and increase risk of arrhythmias, angina or osteoporosis. Use caution in elderly and in patients with coronary artery disease, heart failure, arrhythmias, hypertension, adrenal insufficiency or uncontrolled thyrotoxicosis (contraindicated). Correct adrenal insufficiency before starting. Not for weight loss; high doses can be dangerous.

Reduced absorption with calcium salts,iron salts,aluminium/magnesium antacids,sucralfate,cholestyramine/colestipol,sevelamer; increased requirements with rifampicin,carbamazepine,phenytoin,phenobarbital,sertraline; potentiates warfarin effect (INR monitoring); may alter insulin/oral antidiabetic needs; caution with digoxin (effect may decrease as thyroid status normalizes).

Store below 25°C, protected from light and moisture. Keep in original blister/strip, tightly closed. Keep out of reach of children.

Thyronorm 25 Tablet,Eltroxin 25 Tablet,Thyrox 25 Tablet,Thyrofit 25 Tablet,Tirosint 25 mcg (where available)