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Tablet · 100 mg · 15`S
Before you take it
Use with caution / Consult doctor (may cause fetal harm; effective contraception advised)
Topaz 100 Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Avoid (may increase dizziness, drowsiness and impaired coordination)
Topaz 100 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Topaz 100 Tablet may be needed. Please consult your doctor.
Topaz 100 Tablet should be used with caution in patients with liver disease. Dose adjustment of Topaz 100 Tablet may be needed. Please consult your doctor.
Monograph
Tablet
Treatment of epilepsy/seizure disorders (partial onset seizures, generalized tonic-clonic seizures); prevention of migraine headaches (prophylaxis)
Topiramate is an antiepileptic medicine that stabilizes overactive nerve activity in the brain. It works by modulating voltage-gated sodium channels, enhancing GABA activity, and reducing excitatory glutamate transmission, thereby lowering seizure risk and helping prevent migraines.
Tablet for oral use. Take exactly as prescribed, at the same time each day, with or without food; swallow with water. Do not stop suddenly (may worsen seizures); dose is usually titrated gradually. Maintain adequate fluid intake to reduce kidney stone risk.
Dizziness, sleepiness, fatigue, tingling/numbness (paresthesia), loss of appetite, weight loss, nausea, taste changes, difficulty with concentration/memory, slowed thinking, mood changes
Prescription-only antiepileptic. May cause drowsiness/dizziness—avoid driving or operating machinery until effects are known. Risk of metabolic acidosis, kidney stones, decreased sweating/heat intolerance (especially in children), and acute myopia/secondary angle-closure glaucoma—seek urgent care for eye pain/vision changes. Can cause mood/behavior changes and suicidal thoughts—monitor. Dose adjustment may be needed in kidney disease; caution in liver disease. Do not stop abruptly. May reduce effectiveness of hormonal contraception at higher doses—use additional contraception as advised.
Oral contraceptives (reduced efficacy, especially ethinyl estradiol at higher doses), valproate (hyperammonemia/encephalopathy risk), other CNS depressants/alcohol (increased sedation), carbonic anhydrase inhibitors like acetazolamide (increased kidney stone/metabolic acidosis risk), phenytoin/carbamazepine (may alter topiramate levels), metformin (metabolic acidosis risk), lithium (level changes)
Store below 25°C in a dry place, protected from moisture and light. Keep out of reach of children.
Topamac 100 Tablet, Topirol 100 Tablet, Toperon 100 Tablet, Topiramate 100 mg Tablet (generic), Topaz 100 Tablet (other pack)
At a glance
Good to know
Treatment of epilepsy/seizure disorders (partial onset seizures, generalized tonic-clonic seizures); prevention of migraine headaches (prophylaxis)
Dizziness, sleepiness, fatigue, tingling/numbness (paresthesia), loss of appetite, weight loss, nausea, taste changes, difficulty with concentration/memory, slowed thinking, mood changes
Topiramate is an antiepileptic medicine that stabilizes overactive nerve activity in the brain. It works by modulating voltage-gated sodium channels, enhancing GABA activity, and reducing excitatory glutamate transmission, thereby lowering seizure risk and helping prevent migraines.
Tablet for oral use. Take exactly as prescribed, at the same time each day, with or without food; swallow with water. Do not stop suddenly (may worsen seizures); dose is usually titrated gradually. Maintain adequate fluid intake to reduce kidney stone risk.
Store below 25°C in a dry place, protected from moisture and light. Keep out of reach of children.
Yes, this product requires a valid prescription (Rx). Upload it during checkout when prompted.
Yes. Prices and availability can change based on inventory and serviceability. The latest details are shown at checkout.
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Brand
Intas Pharmaceuticals Ltd
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Manufacturer: INTAS PHARMACEUTICALS`
Medical disclaimer: product information is for awareness only and does not replace medical advice. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalised guidance. Sources: Manufacturer labeling/SmPC, established medical literature (anticonvulsant guidelines), Indian regulatory/pack labeling practices (CDSCO), standard drug references
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