Distributor inventory | Tablet

Type 2 diabetes mellitus—used to improve blood glucose control in adults when diet and exercise alone are insufficient, often as add-on therapy.

Vildagliptin is a DPP-4 inhibitor that increases incretin hormones (GLP-1, GIP), thereby increasing insulin release and reducing glucagon in a glucose-dependent manner. Metformin reduces hepatic glucose production and improves insulin sensitivity; the SR form provides prolonged action with better GI tolerance.

Oral sustained-release tablet. Take exactly as prescribed, usually once daily with the evening meal or as advised. Swallow whole with water; do not crush, break, or chew. Take with food to reduce stomach upset; maintain diet/exercise and monitor glucose regularly.

Nausea, vomiting, diarrhoea, abdominal pain, loss of appetite, headache, dizziness, upper respiratory tract infection, hypoglycaemia (especially with other antidiabetics), skin rash

Prescription-only. Risk of lactic acidosis with metformin—seek urgent care for rapid breathing, severe weakness, muscle pain, abdominal pain, unusual sleepiness. Avoid in severe renal impairment; assess kidney function before start and periodically. Use caution in liver disease, alcoholism, dehydration, severe infection, hypoxia/heart failure. Stop temporarily before iodinated contrast imaging and major surgery as advised. Monitor for pancreatitis symptoms (severe persistent abdominal pain), and for vitamin B12 deficiency with long-term use. Not for type 1 diabetes or diabetic ketoacidosis.

Alcohol (increases lactic acidosis risk), iodinated contrast media, carbonic anhydrase inhibitors (e.g., topiramate, acetazolamide), diuretics, ACE inhibitors, corticosteroids, thyroid hormones, sympathomimetics, other antidiabetics/insulin (increased hypoglycaemia risk), cationic drugs cleared renally (e.g., cimetidine), digoxin (monitor)

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep in original blister pack and out of reach of children.

Galvus Met 50/1000 SR Tablet, Zomelis Met 50/1000 SR Tablet, Jalra-M 50/1000 SR Tablet, Vilda M 50/1000 SR Tablet, Vildamet SR 50/1000 Tablet