ZUROPRAZ 20MG TAB

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Treatment of acid-related disorders such as gastroesophageal reflux disease (GERD), erosive esophagitis, peptic/duodenal ulcers, and Zollinger-Ellison syndrome; also used as part of H. pylori eradication therapy with antibiotics.

Rabeprazole is a proton pump inhibitor (PPI). It irreversibly blocks the H+/K+ ATPase (proton pump) in stomach parietal cells, thereby reducing gastric acid secretion and relieving acidity and ulcer symptoms.

Take by mouth as advised by the doctor. Commonly taken once daily, preferably 30 minutes before food (often before breakfast). Swallow the tablet whole; do not crush or chew.

Headache, diarrhea, nausea, stomach pain, flatulence, dizziness, constipation

Use with caution in severe liver disease. Long-term use may increase risk of vitamin B12 deficiency, low magnesium, bone fractures, and gut infections (e.g., C. difficile). Seek medical advice if you have alarm symptoms such as blood in vomit/black stools, unexplained weight loss, persistent vomiting, or difficulty swallowing. May mask symptoms of gastric cancer; evaluate if symptoms persist. Inform doctor if you have osteoporosis or are on diuretics/digoxin.

Atazanavir/nelfinavir (reduced effect; avoid), warfarin (monitor INR), digoxin (risk of toxicity with low magnesium), methotrexate (high-dose; increased levels), ketoconazole/itraconazole/posaconazole (reduced absorption), erlotinib (reduced effect), clopidogrel (possible reduced activation; monitor/avoid if advised)

Store below 25°C in a cool, dry place. Protect from moisture and light. Keep out of reach of children.

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