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Before you take it
Not recommended (especially in pregnancy); use only if clearly needed and prescribed.
Zyitra 200 Capsule is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Use with caution; avoid excessive alcohol due to increased risk of liver toxicity.
There is limited information available on the use of Zyitra 200 Capsule in patients with kidney disease. Please consult your doctor.
There is limited information available on the use of Zyitra 200 Capsule in patients with liver disease. Please consult your doctor.<br>Inform your doctor if you develop signs of jaundice like yellowing of eyes and skin, itching, and clay colored stools while taking this medicine.
Monograph
Capsule
Treatment of fungal infections such as aspergillosis, histoplasmosis, blastomycosis, onychomycosis (nail fungal infection), and other susceptible systemic or superficial mycoses as prescribed.
Itraconazole is a triazole antifungal that inhibits fungal cytochrome P450 (14-α-demethylase), blocking ergosterol synthesis. This damages the fungal cell membrane and stops fungal growth and replication.
Oral capsule. Take exactly as prescribed, preferably after a full meal for better absorption. Swallow whole; do not crush or chew. If you use acid-reducing medicines, take them as advised by your doctor as they may reduce absorption.
Nausea, vomiting, stomach pain, diarrhea, headache, dizziness, rash, elevated liver enzymes
Prescription-only antifungal. Can cause serious liver injury—seek help for yellowing of eyes/skin, dark urine, severe fatigue or abdominal pain; liver function monitoring may be needed. May worsen heart failure (negative inotropic effect)—avoid/use with extreme caution in patients with congestive heart failure. Numerous drug interactions via CYP3A4—some combinations are contraindicated due to risk of serious heart rhythm problems. Use caution in kidney/liver disease and in elderly.
Contraindicated/major interactions with drugs highly dependent on CYP3A4: simvastatin/lovastatin, certain antiarrhythmics (e.g., quinidine, dofetilide), ergot alkaloids, cisapride, pimozide; increases levels of warfarin, digoxin, cyclosporine/tacrolimus, certain benzodiazepines, calcium channel blockers; reduced absorption with PPIs/H2 blockers/antacids; rifampicin/rifabutin/phenytoin/carbamazepine reduce itraconazole levels.
Store below 25°C in a cool, dry place. Protect from light and moisture. Keep in original pack and out of reach of children.
Canditral 200 Capsule, Itral 200 Capsule, Riconia/Itrazole 200 Capsule, Sporanoxt 200 Capsule, Itaspor 200 Capsule
At a glance
Good to know
Treatment of fungal infections such as aspergillosis, histoplasmosis, blastomycosis, onychomycosis (nail fungal infection), and other susceptible systemic or superficial mycoses as prescribed.
Nausea, vomiting, stomach pain, diarrhea, headache, dizziness, rash, elevated liver enzymes
Itraconazole is a triazole antifungal that inhibits fungal cytochrome P450 (14-α-demethylase), blocking ergosterol synthesis. This damages the fungal cell membrane and stops fungal growth and replication.
Oral capsule. Take exactly as prescribed, preferably after a full meal for better absorption. Swallow whole; do not crush or chew. If you use acid-reducing medicines, take them as advised by your doctor as they may reduce absorption.
Store below 25°C in a cool, dry place. Protect from light and moisture. Keep in original pack and out of reach of children.
Yes, this product requires a valid prescription (Rx). Upload it during checkout when prompted.
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Brand
ZYDUS HEALTHCARE PHARMA
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Manufacturer: ZYDUS HEALTHCARE PHARMA
Medical disclaimer: product information is for awareness only and does not replace medical advice. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalised guidance. Sources: Manufacturer labeling/SmPC, CDSCO/Indian drug labeling requirements, established medical literature (azole antifungals), standard pharmacology references
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