Treatment of fungal infections such as aspergillosis, histoplasmosis, blastomycosis, onychomycosis (nail fungal infection), and other susceptible systemic or superficial mycoses as prescribed.
How It Works
Itraconazole is a triazole antifungal that inhibits fungal cytochrome P450 (14-α-demethylase), blocking ergosterol synthesis. This damages the fungal cell membrane and stops fungal growth and replication.
Directions for Use
Oral capsule. Take exactly as prescribed, preferably after a full meal for better absorption. Swallow whole; do not crush or chew. If you use acid-reducing medicines, take them as advised by your doctor as they may reduce absorption.
Prescription-only antifungal. Can cause serious liver injury—seek help for yellowing of eyes/skin, dark urine, severe fatigue or abdominal pain; liver function monitoring may be needed. May worsen heart failure (negative inotropic effect)—avoid/use with extreme caution in patients with congestive heart failure. Numerous drug interactions via CYP3A4—some combinations are contraindicated due to risk of serious heart rhythm problems. Use caution in kidney/liver disease and in elderly.
Drug Interactions
Contraindicated/major interactions with drugs highly dependent on CYP3A4: simvastatin/lovastatin, certain antiarrhythmics (e.g., quinidine, dofetilide), ergot alkaloids, cisapride, pimozide; increases levels of warfarin, digoxin, cyclosporine/tacrolimus, certain benzodiazepines, calcium channel blockers; reduced absorption with PPIs/H2 blockers/antacids; rifampicin/rifabutin/phenytoin/carbamazepine reduce itraconazole levels.
Manufacturer
ZYDUS HEALTHCARE PHARMA
BrandZYDUS HEALTHCARE PHARMA
Storage Instructions
Store below 25°C in a cool, dry place. Protect from light and moisture. Keep in original pack and out of reach of children.
Treatment of fungal infections such as aspergillosis, histoplasmosis, blastomycosis, onychomycosis (nail fungal infection), and other susceptible systemic or superficial mycoses as prescribed.
Itraconazole is a triazole antifungal that inhibits fungal cytochrome P450 (14-α-demethylase), blocking ergosterol synthesis. This damages the fungal cell membrane and stops fungal growth and replication.
How should I use this medicine?
Oral capsule. Take exactly as prescribed, preferably after a full meal for better absorption. Swallow whole; do not crush or chew. If you use acid-reducing medicines, take them as advised by your doctor as they may reduce absorption.
How should I store this medicine?
Store below 25°C in a cool, dry place. Protect from light and moisture. Keep in original pack and out of reach of children.
Do I need a prescription for this product?
Yes, this product requires a valid prescription (Rx). Upload it during checkout when prompted.
Can prices or availability change?
Yes. Prices and availability can change based on inventory and serviceability. The latest details are shown at checkout.
How do I place an order?
Select a variant, add to cart, enter delivery address, upload prescription if required, and pay securely.
Manufacturer & Brand
Brand:ZYDUS HEALTHCARE PHARMA
Manufacturer:ZYDUS HEALTHCARE PHARMA
HSN Code:30049011
Alternatives
Alternatives are suggested by pharmacists after reviewing your order and prescription.
Disclaimer: Product information is for awareness only and does not replace medical advice. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalized guidance.
Sources: Manufacturer labeling/SmPC, CDSCO/Indian drug labeling requirements, established medical literature (azole antifungals), standard pharmacology references
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