Distributor inventory | Injection

Management of pain and improved mobility in osteoarthritis of the knee (viscosupplementation); may be used for other synovial joint osteoarthritis as advised by a specialist.

Sodium hyaluronate is a natural component of synovial fluid. In osteoarthritis, the quality and quantity of hyaluronic acid in the joint decreases; injecting it helps restore viscoelasticity, improves lubrication and shock absorption, and reduces pain and stiffness.

For intra-articular use only, administered by a trained healthcare professional under aseptic conditions. Dose and schedule depend on product strength and clinician advice (commonly given as a course of injections at weekly intervals). Do not inject intravenously or into infected/inflamed skin areas; rest the joint after injection as advised.

Injection site pain, swelling, warmth, redness, joint effusion, stiffness, transient increase in joint pain, bruising, rash, itching, headache, nausea

Prescription-only; must be injected into the joint by a healthcare professional. Avoid use in patients with hypersensitivity to hyaluronate or any component; caution in patients with allergy to avian proteins/feathers/eggs if product is avian-derived (check label). Do not use in infected joint, skin infections at the injection site, or severe joint inflammation due to infection. Temporary worsening of pain/swelling can occur; seek care for severe pain, fever, marked swelling, or signs of infection. Use with caution in pregnancy/breastfeeding due to limited data.

No clinically significant systemic drug interactions expected due to local intra-articular use; avoid mixing with disinfectants containing quaternary ammonium salts (may precipitate) and avoid concomitant intra-articular use with other injected products unless advised by the specialist.

Store as per label; generally at controlled room temperature, protected from light. Do not freeze. Keep vial in original pack and use immediately after opening; discard unused portion.

Hylan G-F 20 injection (Synvisc), Sodium hyaluronate injection (Hyalgan), Sodium hyaluronate injection (Durolane), Sodium hyaluronate injection (Fermathron), Sodium hyaluronate injection (Orthovisc)