Ablung 100 mg Capsule

Composition of Ablung 100 mg Capsule

Ablung 100 mg Capsule contains Abiraterone acetate 100 mg (capsule). It belongs to the Androgen biosynthesis inhibitor (CYP17 inhibitor) class of medicines.

Uses of Ablung 100 mg Capsule

• Treatment of prostate cancer
• especially metastatic castration-resistant prostate cancer (mCRPC) and metastatic hormone-sensitive prostate cancer
• in combination with prednisone/prednisolone as prescribed.

Key benefits

• Helps slow progression of advanced prostate cancer
• Lowers androgen production that fuels tumor growth
• Used with corticosteroid to improve outcomes
• Can reduce symptoms and delay complications in metastatic disease

How Ablung 100 mg Capsule works

Abiraterone inhibits CYP17 (17α-hydroxylase/C17,20-lyase), a key enzyme in androgen biosynthesis in testes, adrenal glands and tumor tissue. This reduces androgen (testosterone) levels that drive prostate cancer growth. It is usually given with a corticosteroid to reduce mineralocorticoid excess effects.

How to take Ablung 100 mg Capsule

Take exactly as prescribed by an oncologist. Swallow capsule whole with water at the same time each day. Commonly taken on an empty stomach (do not take with food unless your doctor specifically advises), and is usually prescribed along with prednisone/prednisolone. Do not stop corticosteroid abruptly; follow medical advice.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine may be harmful — seek medical advice immediately. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Ablung 100 mg Capsule

Most side effects of Ablung are mild and settle as the body adjusts. Reported side effects include:

• fluid retention/edema
• high blood pressure
• low potassium (hypokalemia)
• liver enzyme elevation
• fatigue
• hot flushes
• joint pain
• nausea
• diarrhea
• headache

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Ablung 100 mg Capsule

Warnings and precautions

Prescription-only anticancer medicine; use under specialist supervision. Can cause severe liver problems—LFT monitoring required and dose interruption may be needed. Risk of hypertension, hypokalemia and fluid retention (mineralocorticoid excess); monitor BP and electrolytes. Avoid in severe hepatic impairment; caution in cardiac disease/heart failure. Do not use in women who are pregnant; men with partners who can become pregnant should use effective contraception during treatment and as advised after stopping.

Do not take Ablung if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Your doctor will confirm this medicine is suitable for you.

Interactions with other medicines

Strong CYP3A4 inducers (e.g., rifampicin, carbamazepine, phenytoin, St John’s wort) may reduce effect; CYP3A4 inhibitors may increase levels. Abiraterone can affect drugs metabolized by CYP2D6 (e.g., metoprolol, propranolol, flecainide, antidepressants) and CYP2C8—dose/monitoring may be needed. Use caution with drugs that lower potassium (loop/thiazide diuretics) and with QT-prolonging medicines.

How to store Ablung 100 mg Capsule

Store below 25°C in a dry place. Protect from moisture and light. Keep in original pack and out of reach of children.

Expert advice for Ablung 100 mg Capsule

Take it at the same time each day and complete the course. Keep your follow-up appointments and any monitoring blood tests.

Manufacturer and class

Manufacturer:

CIPLA LIMITED

Therapeutic class:

Anticancer (Hormonal therapy)

Drug class:

Androgen biosynthesis inhibitor (CYP17 inhibitor)