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Sun Pharma - Capsule - 15 S
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Agomelatine (25mg)
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This medicine needs a prescription.
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Agoprex is used for depression.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Agoprex contains Agomelatine (25mg). It belongs to the Antidepressant class of medicines.
Depression
Agoprex Tablet is a melatonin agonist. It works by resynchronizing the sleep-wake cycle that is disturbed in depression.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Agoprex Tablet may be taken with or without food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Agoprex Tablet, skip it and continue with your normal schedule. Do not double the dose.
An overdose of this medicine can cause fits, dangerous heart rhythm disturbance and coma, and is particularly dangerous with the older tricyclic medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Agoprex are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult doctor |
|---|---|
| Breastfeeding | Breast feeding CONSULT YOUR DOCTOR |
| Alcohol | Consult doctor |
| Driving | Driving UNSAFE |
| Kidney | Kidney CAUTION |
| Liver | Liver UNSAFE |
| Habit forming | No |
These medicines take two to four weeks to begin working, and longer for the full effect. Stopping at two weeks because nothing has changed is the commonest mistake. Never stop suddenly. Abrupt withdrawal causes dizziness, electric-shock sensations, irritability and flu-like symptoms — your doctor will reduce the dose gradually. Tell your doctor or go to hospital immediately if thoughts of harming yourself appear or worsen, particularly in the first weeks or after a dose change, and especially in anyone under twenty-five. Seek urgent care for agitation with fever, shivering, a racing heart, muscle twitching or confusion, particularly if more than one medicine affecting serotonin is being taken. Side effects are usually worst in the first fortnight and then settle.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be combined with a monoamine oxidase inhibitor, or started within the gap your doctor specifies after one.
Tramadol, triptans for migraine, linezolid, St John's wort and other antidepressants can together raise serotonin dangerously. Anti-inflammatory painkillers and blood thinners increase the bleeding risk when combined with this group.
Store at room temperature (below 25°C), protected from light and moisture. Keep out of reach of children.
You have been prescribed Agoprex Tablet for the treatment of depression. It may take a few weeks for this medicine to start working. Keep taking it as prescribed. It should be taken at bedtime. Use caution while driving or doing anything that requires concentration as Agoprex Tablet can cause dizziness and sleepiness. Avoid consuming alcohol while taking this medicine as that may lead to increased side effects. You may need regular blood tests to monitor your liver and kidney functions while you are taking this medication. Inform your doctor if you notice sudden mood changes or develop suicidal thoughts.

Sun Pharma - Capsule - 15 S
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Prescription required
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Prescription required
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The information on Agoprex is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.