
Aknegate Ac Gel
Inex Medicaments Private Limited - Gel - 20 G
Prescription required
Hydrous Benzoyl Peroxide (2.5%w/w) + Adapalene (0.1%w/w)
Aknegate BPO Gel is used for treatment of acne (acne vulgaris) including blackheads, whiteheads and inflammatory pimples.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Aknegate BPO Gel contains Hydrous Benzoyl Peroxide (2.5%w/w) + Adapalene (0.1%w/w). It belongs to the Topical antibacterial/keratolytic (benzoyl peroxide) class of medicines.
Benzoyl peroxide releases active oxygen on the skin, which kills acne-causing bacteria (Cutibacterium acnes). It also has mild keratolytic and comedolytic action that helps unclog pores and reduce inflammation.
For external use only. Clean and dry the affected area, then apply a thin layer once daily initially; may increase to twice daily as tolerated. Avoid eyes, lips, nostrils and broken/irritated skin. Moisturizer and sunscreen may be used; wash hands after application.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Apply it as soon as you remember. If it is nearly time for the next application, skip the missed one — applying extra does not make up for it.
An overdose of this medicine can cause severe irritation when far too much cream is applied; an oral retinoid taken in excess can cause headache, vomiting and liver injury. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Aknegate BPO are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult doctor |
|---|---|
| Breastfeeding | Not recommended while breastfeeding. |
| Alcohol | No known interaction |
| Driving | Not expected to affect your ability to drive. |
| Kidney | Use with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
May cause skin irritation and increased sensitivity to sunlight; use sunscreen and limit sun exposure. Can bleach hair and colored fabrics. Stop use and consult a doctor if severe redness, swelling, blistering or allergic reaction occurs. Use cautiously with other topical acne products (retinoids, salicylic acid) to avoid excessive irritation.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Oral retinoids are absolutely contraindicated in pregnancy and in anyone who might become pregnant without a pregnancy prevention programme. Topical retinoids are avoided in pregnancy.
Other topical irritants/peeling agents (tretinoin/adapalene, salicylic acid, sulfur/resorcinol), alcohol-based astringents/cosmetics; may inactivate/affect stability of topical dapsone (may cause temporary yellow/orange discoloration when used together)
Store below 25°C in a cool, dry place away from heat and direct sunlight. Keep tube tightly closed and out of reach of children.
Apply retinoids at night to clean, dry skin, and moisturise afterwards. Give it at least eight to twelve weeks before judging whether it works. Do not pick or squeeze spots — that is what leaves scars.

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The information on Aknegate BPO Gel is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.