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Prescription requiredEast West PharmaNEURO CNS

Amitrip 50 mg

Amitriptyline (50mg)

Currently out of stock

Same composition, in stock now. Check with your doctor or pharmacist before you switch.

  • Tryptomer 50 Tablet₹94View

Amitrip 50 mg is used for treatment of Depression.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Amitriptyline (50mg)
Available variants: 50 mg 10`S
Best price: ₹35
MRP: ₹37
Prescription: Required
Manufacturer: EAST WEST PHARMA

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Amitrip 50 mg

Amitrip 50 mg contains Amitriptyline (50mg). It belongs to the Antidepressant class of medicines.

Uses of Amitrip 50 mg

Treatment of Depression

Key benefits

  • In Treatment of Depression Amitrip 50mg Tablet helps relieve symptoms of depression by increasing the levels of certain mood-regulating chemicals in the brain. These include serotonin and norepinephrine. It helps improve mood
  • reduces feelings of sadness or hopelessness
  • and improves sleep quality. When used consistently as prescribed by the doctor
  • it can improve a patient’s daily functioning and overall quality of life.

How Amitrip 50 mg works

Amitrip 50mg Tablet contains amitriptyline, an antidepressant (tricyclic antidepressant) that helps overcome depression. It works by increasing certain natural brain chemicals (serotonin and noradrenaline) that improve mood and reduce anxiety. This helps relieve depression and stabilize emotions.

How to take Amitrip 50 mg

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amitrip 50mg Tablet may be taken with or without food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Amitrip 50mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause fits, dangerous heart rhythm disturbance and coma, and is particularly dangerous with the older tricyclic medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Amitrip 50 mg

Most side effects of Amitrip are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Amitrip 50 mg

PregnancyPregnancy CONSULT YOUR DOCTOR
BreastfeedingBreast feeding CONSULT YOUR DOCTOR
AlcoholAlcohol UNSAFE
DrivingDriving UNSAFE
KidneyKidney CAUTION
LiverLiver CAUTION
Habit formingNo

Warnings and precautions

These medicines take two to four weeks to begin working, and longer for the full effect. Stopping at two weeks because nothing has changed is the commonest mistake. Never stop suddenly. Abrupt withdrawal causes dizziness, electric-shock sensations, irritability and flu-like symptoms — your doctor will reduce the dose gradually. Tell your doctor or go to hospital immediately if thoughts of harming yourself appear or worsen, particularly in the first weeks or after a dose change, and especially in anyone under twenty-five. Seek urgent care for agitation with fever, shivering, a racing heart, muscle twitching or confusion, particularly if more than one medicine affecting serotonin is being taken. Side effects are usually worst in the first fortnight and then settle.

Do not take Amitrip if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be combined with a monoamine oxidase inhibitor, or started within the gap your doctor specifies after one.

Interactions with other medicines

Tramadol, triptans for migraine, linezolid, St John's wort and other antidepressants can together raise serotonin dangerously. Anti-inflammatory painkillers and blood thinners increase the bleeding risk when combined with this group.

How to store Amitrip 50 mg

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Amitrip 50 mg

Amitrip 50mg Tablet may cause sleepiness. Take it at bedtime and do not drive or perform any activity requiring concentration until you know how it affects you. Avoid consuming alcohol while taking Amitrip 50mg Tablet, as it may cause excessive sleepiness. Monitor your weight during treatment, as this medicine can cause weight gain and increased appetite. It may cause a sudden drop in blood pressure. Rise slowly if you have been sitting or lying down. Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts. Pay close attention to any changes, especially sudden changes, in mood, behavior, thoughts, or feelings. This is particularly important when the medicine is started or when the dose is changed. This medication can significantly reduce saliva production, leading to dry mouth (xerostomia). Maintain strict oral hygiene by brushing twice daily with toothpaste and flossing regularly. This medication may reduce tear production, leading to dry eyes. If you wear contact lenses, your doctor may advise using preservative-free lubricating eye drops to maintain proper eye and lens hygiene.

Manufacturer and class

Manufacturer:
EAST WEST PHARMA
Therapeutic class:
NEURO CNS
Drug class:
Antidepressant
Chemical class:
Dibenzocycloheptenes

Substitutes for Amitrip 50 mg

Medicines with the same active ingredient (Amitriptyline (50mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Amitrip 50 mg
Tryptomer 50 TabletDr Reddys Laboratories Ltdtablet · 15 Tablet₹94165% more
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Amitrip 50 mg FAQs

What is Amitrip 50 mg used for?
Amitrip 50 mg is commonly used for Treatment of Depression. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Amitrip 50 mg?
Amitrip 50 mg contains Amitriptyline (50mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Amitrip 50 mg?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Amitrip 50 mg work?
Amitrip 50mg Tablet contains amitriptyline, an antidepressant (tricyclic antidepressant) that helps overcome depression.
Is Amitrip 50 mg a prescription medicine?
Yes. Amitrip 50 mg is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Amitrip 50 mg?
The side effects reported most often with Amitrip are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Amitrip 50 mg be taken during pregnancy?
Pregnancy CONSULT YOUR DOCTOR Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Amitrip.
Can I drink alcohol while taking Amitrip 50 mg?
Alcohol UNSAFE
What if I miss a dose of Amitrip 50 mg?
If you miss a dose of Amitrip 50mg Tablet, take it as soon as possible.
Is Amitrip 50 mg habit forming?
No. Amitrip 50 mg is not known to be habit forming when taken as prescribed.
How much does Amitrip 50 mg cost on PingMeDoc Pharmacy?
Amitrip 50 mg starts at ₹35 (MRP ₹37) on PingMeDoc Pharmacy. Available in 50 mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Amitrip 50 mg?
Amitrip 50 mg is manufactured by EAST WEST PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Amitrip 50 mg delivered?
Amitrip 50 mg is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Amitrip 50 mg, Quick facts

Salt
Amitriptyline (50mg)
Best price
₹35
MRP
₹37
Prescription
Required (Rx)
Schedule
Schedule H
Brand
EAST WEST PHARMA
Manufacturer
EAST WEST PHARMA
Therapeutic class
NEURO CNS
Drug class
Antidepressant
Chemical class
Dibenzocycloheptenes
Action class
Tricyclic Antidepressants (TCAs)
Habit forming
No
Variants
50 mg 10`S
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Amitrip 50 mg.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.