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Prescription requiredJB ChemicalsAnorectal preparations / Topical anti-infective with local anesthetic

Ano-Metrogyl Cream

Lidocaine (4% w/w) + Metronidazole (1% w/w) + Sucralfate (7% w/w)

Ano-Metrogyl Cream is used for local treatment for anorectal conditions such as anal fissure and hemorrhoids (piles) with associated pain, burning/itching and suspected/associated local infection.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

₹189₹7.56 per g
Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Lidocaine (4% w/w) + Metronidazole (1% w/w) + Sucralfate (7% w/w)
Available variants: cream cream 25GM
Best price: ₹189 (₹7.56 per g)
Prescription: Required
Manufacturer: JB CHEMICALS

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Same salt, lower price

Medicines with the same active ingredient and strength as Ano-Metrogyl Cream.

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Ano-Metrogyl Cream

cream - 25 g

₹189

₹7.56 per g

  • Anosum Cream

    Samarth Life Sciences Pvt Ltd · cream - 20 g · Rx

    ₹92

    ₹4.59 per g

    Save 39%
Compare all substitutes
Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Ano-Metrogyl Cream. The medicine inside is the same — the brand name, manufacturer and price are what differ.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Composition of Ano-Metrogyl Cream

Ano-Metrogyl Cream contains Lidocaine (4% w/w) + Metronidazole (1% w/w) + Sucralfate (7% w/w). It belongs to the Nitroimidazole antibiotic + Amide local anesthetic class of medicines.

Uses of Ano-Metrogyl Cream

  • Local treatment for anorectal conditions such as anal fissure and hemorrhoids (piles) with associated pain
  • burning/itching and suspected/associated local infection

Key benefits

  • Helps reduce pain and burning in anal fissure/piles
  • Provides local numbness for quick relief
  • Helps control local anaerobic infection
  • Reduces irritation and discomfort during healing

How Ano-Metrogyl Cream works

Metronidazole is an antibacterial/antiprotozoal that inhibits DNA synthesis in susceptible anaerobic bacteria, reducing local infection and inflammation. Lidocaine is a local anesthetic that blocks nerve sodium channels to numb the area and provide rapid pain relief.

How to take Ano-Metrogyl Cream

For external use only. Clean and dry the affected anal area; apply a thin layer as advised by a doctor (commonly 2–3 times daily). Wash hands before and after application; avoid contact with eyes/mouth and do not apply on large open wounds unless prescribed.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of ANO-metrogyl Cream, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine is unlikely from external use. It can cause vomiting, severe loose motions and nerve symptoms. It may cause bloating and loose motions. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Ano-Metrogyl Cream

Most side effects of Ano-Metrogyl are mild and settle as the body adjusts. Reported side effects include:

  • Application site burning
  • itching
  • irritation
  • redness
  • dryness
  • numbness/tingling
  • allergic rash

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Ano-Metrogyl Cream

PregnancyConsult doctor
BreastfeedingBreast feeding CONSULT YOUR DOCTOR
AlcoholUse with caution (avoid alcohol if significant absorption is expected; risk of disulfiram-like reaction with metronidazole)
DrivingDriving
KidneyKidney CONSULT YOUR DOCTOR
LiverLiver CONSULT YOUR DOCTOR
Habit formingNo

Warnings and precautions

External use only; do not ingest. Stop and seek medical advice if severe irritation, rash, swelling, bleeding, or no improvement occurs. Use with caution in patients with known allergy to metronidazole/nitroimidazoles or local anesthetics (amide type). Avoid prolonged or excessive use; apply only to affected area. Consult doctor before use in children, during pregnancy or breastfeeding.

Do not take Ano-Metrogyl if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for use on large burns or deep wounds without medical advice. Probiotics are used with caution in people whose immune system is significantly suppressed.

Interactions with other medicines

With excessive use/absorption: warfarin and other anticoagulants (increased bleeding risk with metronidazole), disulfiram (neuropsychiatric reactions), alcohol (disulfiram-like reaction), other local anesthetics/antiarrhythmics (additive lidocaine effects)

How to store Ano-Metrogyl Cream

Store below 25°C in a cool, dry place. Protect from light and moisture. Keep tube tightly closed and out of reach of children.

Expert advice for Ano-Metrogyl Cream

ANO-metrogyl Cream is prescribed to relieve pain, swelling, and other discomfort in the rectal area caused by fissures. In addition to using ANO-metrogyl Cream, you may take warm sitz baths, which can help soothe the area and ease pain. Do not ignore the urge to defecate. Delaying bowel movements can lead to the formation of harder, larger stools that are more difficult and painful to pass. Avoid taking any oral laxatives along with ANO-metrogyl Cream unless advised by your doctor. Some medicines, such as iron supplements or certain antibiotics, can make stools harder to pass. Inform your doctor if you are taking any of these. A fiber-rich diet (including wholegrain bread, cereals, fruits, and green leafy vegetables), adequate hydration with six to eight glasses of water daily, and regular physical activity are essential for maintaining healthy bowel movements and preventing constipation.

Manufacturer and class

Manufacturer:
JB CHEMICALS
Therapeutic class:
Anorectal preparations / Topical anti-infective with local anesthetic
Drug class:
Nitroimidazole antibiotic + Amide local anesthetic

Substitutes for Ano-Metrogyl Cream

Medicines with the same active ingredient (Lidocaine (4% w/w) + Metronidazole (1% w/w) + Sucralfate (7% w/w)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Ano-Metrogyl Cream
Anosum CreamSamarth Life Sciences Pvt Ltdcream · 20GM₹9251% cheaper
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Ano-Metrogyl Cream FAQs

What is Ano-Metrogyl Cream used for?
Ano-Metrogyl Cream is commonly used for Local treatment for anorectal conditions such as anal fissure and hemorrhoids (piles) with associated pain, burning/itching and suspected/associated local infection. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Ano-Metrogyl Cream?
Ano-Metrogyl Cream contains Lidocaine (4% w/w) + Metronidazole (1% w/w) + Sucralfate (7% w/w). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Ano-Metrogyl Cream?
For external use only. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Ano-Metrogyl Cream work?
Metronidazole is an antibacterial/antiprotozoal that inhibits DNA synthesis in susceptible anaerobic bacteria, reducing local infection and inflammation.
Is Ano-Metrogyl Cream a prescription medicine?
Yes. Ano-Metrogyl Cream is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Ano-Metrogyl Cream?
The side effects reported most often with Ano-Metrogyl are Application site burning, itching, irritation, redness, dryness. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Ano-Metrogyl Cream be taken during pregnancy?
Consult doctor Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Ano-Metrogyl.
Can I drink alcohol while taking Ano-Metrogyl Cream?
Use with caution (avoid alcohol if significant absorption is expected; risk of disulfiram-like reaction with metronidazole)
What if I miss a dose of Ano-Metrogyl Cream?
If you miss a dose of ANO-metrogyl Cream, use it as soon as possible.
Is Ano-Metrogyl Cream habit forming?
No. Ano-Metrogyl Cream is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Ano-Metrogyl Cream?
Anosum Cream has the same active ingredient and strength and is listed from ₹92 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Ano-Metrogyl Cream cost on PingMeDoc Pharmacy?
Ano-Metrogyl Cream starts at ₹189 on PingMeDoc Pharmacy. Available in cream cream 25GM. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Ano-Metrogyl Cream?
Ano-Metrogyl Cream is manufactured by JB CHEMICALS. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Ano-Metrogyl Cream delivered?
Ano-Metrogyl Cream is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Ano-Metrogyl Cream, Quick facts

Salt
Lidocaine (4% w/w) + Metronidazole (1% w/w) + Sucralfate (7% w/w)
Form
cream
Best price
₹189 (₹7.56 per g)
Prescription
Required (Rx)
Schedule
Schedule H
Brand
JB CHEMICALS
Manufacturer
JB CHEMICALS
Therapeutic class
Anorectal preparations / Topical anti-infective with local anesthetic
Drug class
Nitroimidazole antibiotic + Amide local anesthetic
Habit forming
No
Variants
cream cream 25GM
Delivery
Standard across India

References

The information on Ano-Metrogyl Cream is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Manufacturer labeling/pack insert, established medical literature on metronidazole and lidocaine, standard clinical references for anorectal topical therapies
  2. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  3. National List of Essential Medicines (NLEM) 2022, Government of India.
  4. Manufacturer's package insert / prescribing information for Ano-Metrogyl Cream.
  5. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.