BD Tofa XR 11 mg Tablet

Composition of BD Tofa XR 11 mg Tablet

BD Tofa XR 11 mg Tablet contains Tofacitinib extended-release 11 mg. It belongs to the Janus kinase (JAK) inhibitor class of medicines.

Uses of BD Tofa XR 11 mg Tablet

• Treatment of moderate to severe rheumatoid arthritis in adults (when response to DMARDs like methotrexate is inadequate)
• psoriatic arthritis in adults
• and moderate to severe ulcerative colitis in adults (as prescribed by specialist).

Key benefits

• Reduces joint pain and swelling in rheumatoid arthritis
• Improves physical function and disease control in psoriatic arthritis
• Helps induce/maintain remission in ulcerative colitis (selected patients)
• Lowers inflammatory markers and flare frequency

How BD Tofa XR 11 mg Tablet works

Tofacitinib is a Janus kinase (JAK) inhibitor that reduces inflammatory signaling by inhibiting JAK enzymes involved in cytokine pathways. This lowers immune-mediated inflammation and helps reduce joint pain/swelling and gut inflammation in eligible patients.

How to take BD Tofa XR 11 mg Tablet

Oral tablet (extended-release). Take 1 tablet once daily, preferably at the same time each day, with or without food. Swallow whole; do not crush, break, or chew. Use only as prescribed; regular lab monitoring is required.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can seriously suppress the bone marrow and damage the liver. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of BD Tofa XR 11 mg Tablet

Most side effects of BD Tofa XR are mild and settle as the body adjusts. Reported side effects include:

• Upper respiratory tract infection
• headache
• diarrhea
• nausea
• nasopharyngitis
• increased cholesterol
• elevated liver enzymes
• hypertension
• rash

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for BD Tofa XR 11 mg Tablet

Warnings and precautions

Prescription-only immunosuppressant. Increases risk of serious infections (including TB, fungal and opportunistic infections); screen for TB/hepatitis and monitor. Risk of blood clots (DVT/PE), major cardiovascular events and malignancy may be increased in certain patients; use lowest effective dose and assess risk factors (age, smoking, cardiovascular history). Monitor CBC (lymphocytes/neutrophils/hemoglobin), liver enzymes, lipids; dose adjustments/avoid in severe hepatic impairment and severe renal impairment as advised. Avoid live vaccines during and shortly after treatment. Not recommended in active serious infections; seek urgent care for fever, cough, breathlessness, chest pain, leg swelling, or unusual bleeding/bruising.

Do not take BD Tofa XR if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active serious infection, or with severe liver or bone-marrow disease. Several of these medicines must not be used in pregnancy.

Interactions with other medicines

Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin) may increase levels; strong CYP3A4 inducers (e.g., rifampicin, carbamazepine, phenytoin, St John’s wort) may reduce effect; moderate CYP3A4 inhibitors with strong CYP2C19 inhibitors (e.g., fluconazole) increase exposure; other immunosuppressants/biologics (e.g., azathioprine, cyclosporine, tacrolimus, TNF inhibitors) increase infection risk; live vaccines should be avoided.

How to store BD Tofa XR 11 mg Tablet

Store at room temperature (below 25°C), in original blister pack, protected from moisture and light. Keep out of reach of children.

Expert advice for BD Tofa XR 11 mg Tablet

Keep every monitoring blood test appointment. Carry a note of the medicine and its schedule, especially for weekly dosing.

Manufacturer and class

Manufacturer:

BDR PHARMACEUTICALS INTERNATIO

Therapeutic class:

prescription

Drug class:

Janus kinase (JAK) inhibitor