
Actibile 150MG Tab
Zydus Healthcare Pharma - Tablet - 150 mg - 10 S
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Sertaconazole (2%w/w) + Beclomethasone (0.025%w/w)
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Biwork Cream is used for biwork Cream is used in the treatment of skin infections.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Biwork Cream contains Sertaconazole (2%w/w) + Beclomethasone (0.025%w/w). It belongs to the Antifungal and Inhaled bronchodilator / corticosteroid class of medicines.
Biwork Cream is used in the treatment of skin infections.
Biwork Cream is a combination of two medicines: Sertaconazole and Beclometasone, which treats skin infections. Sertaconazole is an antifungal which stops the growth of fungi on the skin by preventing them from forming their own protective covering. Beclometasone is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy.
Clean and dry the affected area, then apply a thin layer and rub it in gently. Wash your hands before and after use, unless your hands are the area being treated. This is for use on the skin only — do not swallow it. Follow the dose and the duration written on your prescription.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Apply it as soon as you remember. If it is nearly time for the next application, skip the missed one — applying extra does not make up for it.
An overdose of this medicine is unlikely from skin use; swallowing the preparation may cause stomach upset. It can cause a racing heart, marked tremor, headache and a fall in blood potassium. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Biwork are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Biwork Cream may be unsafe to use during pregnancy.<br/>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | Biwork Cream is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby. |
| Alcohol | Alcohol may worsen the side effects of this medicine. Limit it. |
| Driving | Not expected to affect your ability to drive. |
| Kidney | No dose change is usually needed in kidney disease. |
| Liver | Use with caution if you have liver disease — your doctor may adjust the dose or monitor your liver function. |
| Habit forming | No |
Keep applying for the full period your doctor stated, usually two to four weeks, and for a week or two after the rash has cleared. Stopping when it looks better is why ringworm keeps coming back. Apply a little beyond the visible edge of the patch — the fungus extends further than the redness. Do not use a combination cream containing a steroid on a fungal infection unless a doctor has specifically prescribed it. The steroid calms the redness while the fungus spreads underneath. See a doctor if the rash covers a large area, involves the scalp or nails, or has not improved in two weeks — these usually need tablets as well. Know which of your inhalers is the reliever and which is the preventer. A preventer must be used every day even when you feel well; a reliever is for symptoms. Seek emergency care if your reliever is not working, if you cannot speak a full sentence, or if you are using the reliever far more often than usual. Rinse your mouth with water and spit it out after every steroid inhaler dose to prevent thrush and hoarseness. Ask your doctor or pharmacist to watch your technique — poor technique is the commonest reason an inhaler seems not to work. Use a spacer if one has been advised, particularly for children.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. For external use only. Not for use in the eyes. Not for anyone with a known allergy to the propellant used in the inhaler.
No significant interactions are expected from preparations used on the skin. Beta blockers, including eye drops for glaucoma, can tighten the airways and reduce the effect of your reliever.
Store below 30°C, away from direct sunlight. Close the cap tightly after each use. Keep out of the reach of children.
<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>You have been prescribed Biwork Cream for the treatment of fungal skin infections.</li> <li>It is for use on skin only. Do not use it in your eyes, mouth, or vagina. Rinse with cold water if you accidentally get it in these areas.</li> <li>Do not cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.</li> <li>If you think the area of skin you are treating has become more irritated and infected, you should stop using Biwork Cream and consult your doctor.</li> <li>Do not use this medicine more often or for longer than advised by your doctor. Inform your doctor if the treated skin area does not improve after 2 weeks of treatment.</li></ul></div></div></div></div></div></div>

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The information on Biwork Cream is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.