
Augmentin 1000MG Duo
Glaxo Smithkline Pharma - 1000 mg - 10 S
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Paracetamol (650mg)
Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.
Calpol + 650 mg Tablet is used for pain relief Treatment of Fever.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Medicines with the same active ingredient and strength as Calpol + 650 mg Tablet.
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Calpol + 650 mg Tablet
tablet - 650 mg - 15 S
₹31
₹2.04 per tablet
DHURUDHURI PHARMACEUTICALS · tablet - 650 mg - 10 S
₹17
₹1.69 per tablet
MICRO LABS · tablet - 15 Tablet
₹29
₹1.93 per tablet
DEEKAY LIFE SCIENCE · tablet - 650mg - 10 S
₹20
₹2.00 per tablet
A substitute contains the same active ingredient (salt), in the same strength, as Calpol + 650 mg Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.
All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.
Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.
Calpol + 650 mg Tablet contains Paracetamol (650mg). It belongs to the Para-aminophenol derivative class of medicines.
Pain relief Treatment of Fever
Calpol 650 Plus Tablet is an analgesic (pain reliever) and anti-pyretic (fever reducer). It works by blocking the release of certain chemical messengers that cause pain and fever.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Calpol 650mg Tablet should be taken with or after food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Calpol 650mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
An overdose of this medicine can cause severe and sometimes fatal liver damage, often with no symptoms at all for the first day. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Calpol + are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Calpol 650 Plus Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. |
|---|---|
| Breastfeeding | Calpol 650 Plus Tablet is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby. |
| Alcohol | It is unsafe to consume alcohol with Calpol 650 Plus Tablet . |
| Driving | Driving SAFE |
| Kidney | Calpol 650 Plus Tablet should be used with caution in patients with kidney disease. Dose adjustment of Calpol 650 Plus Tablet may be needed. Please consult your doctor.However, Calpol 650 Plus Tablet contains paracetamol which is considered the safest painkiller for kidney disease patients. |
| Liver | Calpol 650 Plus Tablet should be used with caution in patients with liver disease. Dose adjustment of Calpol 650 Plus Tablet may be needed. Please consult your doctor.However, the use of Calpol 650 Plus Tablet is not recommended in patients with severe liver disease and active liver disease. |
| Habit forming | No |
Never exceed the daily maximum printed on the pack. Paracetamol overdose damages the liver, and the damage can be silent for a day or two before it becomes serious. Check every other medicine you are taking. Paracetamol is in a very large number of cold, flu and pain combinations, and the doses add together. If you drink alcohol regularly, or have liver disease, ask your doctor what daily limit is safe for you. See a doctor if fever lasts more than three days, or pain more than five.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe liver disease, except under medical supervision.
Regular alcohol use increases the risk of liver injury. Tell your doctor if you are on warfarin — regular high-dose paracetamol can affect it.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Calpol 650mg Tablet can be taken with or without food, but taking it with food or milk may help reduce stomach discomfort. Avoid taking more than the recommended dose, as excessive use can increase the risk of liver damage. Check the labels of other “cold and flu” medicines, as many may also contain paracetamol. Taking them together can lead to an overdose. Avoid alcohol while taking Calpol 650mg Tablet, as it may increase the risk of liver damage. Inform your doctor if you have liver or kidney disease, as dose adjustment or monitoring may be required, especially with long-term use. Seek medical advice if you notice symptoms such as dark urine, yellowing of the skin or eyes, or unusual tiredness. These may indicate liver problems. Consult your doctor if the fever or pain lasts for more than a few days.
Medicines with the same active ingredient (Paracetamol (650mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Calpol + 650 mg Tablet |
|---|---|---|---|
| 2D Para 650 mg TabletDHURUDHURI PHARMACEUTICALS | tablet · 10`S | ₹17 | 45% cheaper |
| Xtpara 650 Tablet | 1X10 | ₹19 | 38% cheaper |
| Glenpar 650 Tablet | 1X10 | ₹19 | 38% cheaper |
| Merimol 650 mg Tablet | 10 | ₹20 | 36% cheaper |
| PA 650 TabletDEEKAY LIFE SCIENCE | tablet · 10`S | ₹20 | 35% cheaper |
| Paracin 650 mg TabletSTADMED (P) LTD | tablet · 10`S | ₹20 | 34% cheaper |
| K-Par 650 TabletKINESIS PHARMACEUTICALS (P) LTD.` | tablet · 10`S | ₹20 | 34% cheaper |
| Dart 650 TabletJUGGAT PHARMA` | tablet · 10`S | ₹20 | 34% cheaper |
| Colsun-650 Tablet | 1 | ₹22 | 29% cheaper |
| Dolo 650 TabletMICRO LABS | tablet · 15 Tablet | ₹29 | 6% cheaper |
| 99F 650 TabletFDC Ltd | tablet · 15`S | ₹30 | 2% cheaper |
| Medomol 650 TabletMEDOPHARM | tablet · 15`S | ₹31 | same price |

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The information on Calpol + 650 mg Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.