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OTC · No prescriptionGlaxo Smithkline PharmaPAIN ANALGESICS

Calpol + 650 mg Tablet

Paracetamol (650mg)

₹31MRP ₹32In stock
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Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.

Calpol + 650 mg Tablet is used for pain relief Treatment of Fever.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Paracetamol (650mg)
Available variants: tablet 650 mg 15`S
Best price: ₹31 (₹2.04 per tablet)
MRP: ₹32
Prescription: Not required
Manufacturer: GLAXO SMITHKLINE PHARMA

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Same salt, lower price

Medicines with the same active ingredient and strength as Calpol + 650 mg Tablet.

You are viewing

Calpol + 650 mg Tablet

tablet - 650 mg - 15 S

₹31

₹2.04 per tablet

  • 2D Para 650MG Tab

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    ₹1.69 per tablet

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  • Dolo 650 Tablet

    MICRO LABS · tablet - 15 Tablet

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    ₹1.93 per tablet

  • PA 650 Tab 10S

    DEEKAY LIFE SCIENCE · tablet - 650mg - 10 S

    ₹20

    ₹2.00 per tablet

Compare all substitutes
Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Calpol + 650 mg Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Composition of Calpol + 650 mg Tablet

Calpol + 650 mg Tablet contains Paracetamol (650mg). It belongs to the Para-aminophenol derivative class of medicines.

Uses of Calpol + 650 mg Tablet

Pain relief Treatment of Fever

Key benefits

  • In Pain relief Calpol 650mg Tablet works by blocking pain signals in the brain
  • helping reduce the sensation of pain. This leads to relief from discomfort and improves daily functioning
  • making the patients feel more comfortable and active. In Treatment of Fever Calpol 650mg Tablet helps reduce fever by lowering the body’s temperature through its action on the brain. This helps lower high temperatures and relieves associated symptoms such as chills and body aches. Managing fever can prevent dehydration and excessive discomfort. As a result
  • patients may feel better and recover more comfortably. Show More

How Calpol + 650 mg Tablet works

Calpol 650 Plus Tablet is an analgesic (pain reliever) and anti-pyretic (fever reducer). It works by blocking the release of certain chemical messengers that cause pain and fever.

How to take Calpol + 650 mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Calpol 650mg Tablet should be taken with or after food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Calpol 650mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause severe and sometimes fatal liver damage, often with no symptoms at all for the first day. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Calpol + 650 mg Tablet

Most side effects of Calpol + are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Calpol + 650 mg Tablet

PregnancyCalpol 650 Plus Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
BreastfeedingCalpol 650 Plus Tablet is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
AlcoholIt is unsafe to consume alcohol with Calpol 650 Plus Tablet .
DrivingDriving SAFE
KidneyCalpol 650 Plus Tablet should be used with caution in patients with kidney disease. Dose adjustment of Calpol 650 Plus Tablet may be needed. Please consult your doctor.However, Calpol 650 Plus Tablet contains paracetamol which is considered the safest painkiller for kidney disease patients.
LiverCalpol 650 Plus Tablet should be used with caution in patients with liver disease. Dose adjustment of Calpol 650 Plus Tablet may be needed. Please consult your doctor.However, the use of Calpol 650 Plus Tablet is not recommended in patients with severe liver disease and active liver disease.
Habit formingNo

Warnings and precautions

Never exceed the daily maximum printed on the pack. Paracetamol overdose damages the liver, and the damage can be silent for a day or two before it becomes serious. Check every other medicine you are taking. Paracetamol is in a very large number of cold, flu and pain combinations, and the doses add together. If you drink alcohol regularly, or have liver disease, ask your doctor what daily limit is safe for you. See a doctor if fever lasts more than three days, or pain more than five.

Do not take Calpol + if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe liver disease, except under medical supervision.

Interactions with other medicines

Regular alcohol use increases the risk of liver injury. Tell your doctor if you are on warfarin — regular high-dose paracetamol can affect it.

How to store Calpol + 650 mg Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Calpol + 650 mg Tablet

Calpol 650mg Tablet can be taken with or without food, but taking it with food or milk may help reduce stomach discomfort. Avoid taking more than the recommended dose, as excessive use can increase the risk of liver damage. Check the labels of other “cold and flu” medicines, as many may also contain paracetamol. Taking them together can lead to an overdose. Avoid alcohol while taking Calpol 650mg Tablet, as it may increase the risk of liver damage. Inform your doctor if you have liver or kidney disease, as dose adjustment or monitoring may be required, especially with long-term use. Seek medical advice if you notice symptoms such as dark urine, yellowing of the skin or eyes, or unusual tiredness. These may indicate liver problems. Consult your doctor if the fever or pain lasts for more than a few days.

Manufacturer and class

Manufacturer:
GLAXO SMITHKLINE PHARMA
Therapeutic class:
PAIN ANALGESICS
Drug class:
Para-aminophenol derivative
Chemical class:
1- hydroxy- 2- unsubstituted benzenoids

Substitutes for Calpol + 650 mg Tablet

Medicines with the same active ingredient (Paracetamol (650mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Calpol + 650 mg Tablet
2D Para 650 mg TabletDHURUDHURI PHARMACEUTICALStablet · 10`S₹1745% cheaper
Xtpara 650 Tablet1X10₹1938% cheaper
Glenpar 650 Tablet1X10₹1938% cheaper
Merimol 650 mg Tablet10₹2036% cheaper
PA 650 TabletDEEKAY LIFE SCIENCEtablet · 10`S₹2035% cheaper
Paracin 650 mg TabletSTADMED (P) LTDtablet · 10`S₹2034% cheaper
K-Par 650 TabletKINESIS PHARMACEUTICALS (P) LTD.`tablet · 10`S₹2034% cheaper
Dart 650 TabletJUGGAT PHARMA`tablet · 10`S₹2034% cheaper
Colsun-650 Tablet1₹2229% cheaper
Dolo 650 TabletMICRO LABStablet · 15 Tablet₹296% cheaper
99F 650 TabletFDC Ltdtablet · 15`S₹302% cheaper
Medomol 650 TabletMEDOPHARMtablet · 15`S₹31same price
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Calpol + 650 mg Tablet FAQs

What is Calpol + 650 mg Tablet used for?
Calpol + 650 mg Tablet is commonly used for Pain relief Treatment of Fever. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Calpol + 650 mg Tablet?
Calpol + 650 mg Tablet contains Paracetamol (650mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Calpol + 650 mg Tablet?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Calpol + 650 mg Tablet work?
Calpol 650 Plus Tablet is an analgesic (pain reliever) and anti-pyretic (fever reducer).
Is Calpol + 650 mg Tablet a prescription medicine?
No. Calpol + 650 mg Tablet is available over the counter (OTC), no prescription is required. However, it is always safer to consult a doctor or pharmacist before use.
What are the common side effects of Calpol + 650 mg Tablet?
The side effects reported most often with Calpol + are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Calpol + 650 mg Tablet be taken during pregnancy?
Calpol 650 Plus Tablet may be unsafe to use during pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Calpol +.
Can I drink alcohol while taking Calpol + 650 mg Tablet?
It is unsafe to consume alcohol with Calpol 650 Plus Tablet .
What if I miss a dose of Calpol + 650 mg Tablet?
If you miss a dose of Calpol 650mg Tablet, take it as soon as possible.
Is Calpol + 650 mg Tablet habit forming?
No. Calpol + 650 mg Tablet is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Calpol + 650 mg Tablet?
2D Para 650 mg Tablet has the same active ingredient and strength and is listed from ₹17 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Calpol + 650 mg Tablet cost on PingMeDoc Pharmacy?
Calpol + 650 mg Tablet starts at ₹31 (MRP ₹32) on PingMeDoc Pharmacy. Available in tablet 650 mg 15`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Calpol + 650 mg Tablet?
Calpol + 650 mg Tablet is manufactured by GLAXO SMITHKLINE PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Calpol + 650 mg Tablet delivered?
Calpol + 650 mg Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Calpol + 650 mg Tablet, Quick facts

Salt
Paracetamol (650mg)
Form
tablet
Best price
₹31 (₹2.04 per tablet)
MRP
₹32
Prescription
Not required (OTC)
Brand
GLAXO SMITHKLINE PHARMA
Manufacturer
GLAXO SMITHKLINE PHARMA
Therapeutic class
PAIN ANALGESICS
Drug class
Para-aminophenol derivative
Chemical class
1- hydroxy- 2- unsubstituted benzenoids
Action class
Analgesic & Antipyretic-PCM
Habit forming
No
Variants
tablet 650 mg 15`S
Delivery
Standard across India

References

The information on Calpol + 650 mg Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Calpol + 650 mg Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.