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Prescription requiredZydus Healthcare PharmaTopical corticosteroid

Clop Lotion

Clobetasol (0.05%w/v)

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Clop Lotion is used for clop Lotion is used in the treatment of skin infections.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Clobetasol (0.05%w/v)
Available variants: lotion 0.05%w/v 20ML
Best price: ₹85 (₹4.23 per ml)
MRP: ₹89
Prescription: Required
Manufacturer: ZYDUS HEALTHCARE PHARMA

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Clop Lotion

Clop Lotion contains Clobetasol (0.05%w/v). It belongs to the Corticosteroid / calcineurin inhibitor class of medicines.

Uses of Clop Lotion

Clop Lotion is used in the treatment of skin infections.

Key benefits

  • Rapid relief of itching and inflammation
  • Acts where it is applied

How Clop Lotion works

Clop Lotion is a steroid. It works by blocking the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy.

How to take Clop Lotion

Clean and dry the affected area, then apply a thin layer and rub it in gently. Wash your hands before and after use, unless your hands are the area being treated. This is for use on the skin only — do not swallow it. Follow the dose and the duration written on your prescription.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Apply it as soon as you remember. If it is nearly time for the next application, skip the missed one — applying extra does not make up for it.

If you take too much

An overdose of this medicine can suppress the body's own steroid production when it is used for a long time over large areas, especially in children. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Clop Lotion

Most side effects of Clop are mild and settle as the body adjusts. Reported side effects include:

  • Burning or stinging
  • Thinning of the skin
  • Stretch marks
  • Acne
  • Change in skin colour

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Clop Lotion

PregnancyClop Lotion may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
BreastfeedingClop Lotion is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
AlcoholNo significant interaction with alcohol is expected.
DrivingNot expected to affect your ability to drive.
KidneyNo dose change is usually needed in kidney disease.
LiverNo dose change is usually needed in liver disease.
Habit formingNo

Warnings and precautions

Use it only on the area and for the number of days your doctor specified. Potent steroid creams thin the skin permanently when used for too long. Never use a potent steroid cream on the face, the groin or the underarms unless your doctor has specifically told you to — the skin there is thin and absorbs much more. Do not use it on an infection. A steroid on ringworm, impetigo or herpes makes the infection worse while hiding it. Do not use leftover cream on a new rash, and never pass it to someone else. Stop and see your doctor if the area becomes more painful, weepy or crusted.

Do not take Clop if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for untreated bacterial, fungal or viral skin infections. Not for use in or around the eyes.

Interactions with other medicines

No significant interactions are expected from preparations used on the skin.

How to store Clop Lotion

Store below 30°C, away from direct sunlight. Close the cap tightly after each use. Keep out of the reach of children.

Expert advice for Clop Lotion

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>Topclo 0.05% Lotion is used to treat redness, swelling, itching, and discomfort of various skin conditions.</li> <li>It should be applied to the affected areas as a thin film two or three times daily, or as advised by your doctor.</li> <li>Don't use it more often or for longer than advised by your doctor.</li> <li>Don't cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.</li> <li>If you think the area of skin you are treating has become infected you should stop using Topclo 0.05% Lotion and consult your doctor.</li> <li>Consult your doctor if your skin condition has not improved after 2 weeks of treatment. </li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:
ZYDUS HEALTHCARE PHARMA
Therapeutic class:
Topical corticosteroid
Drug class:
Corticosteroid / calcineurin inhibitor

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Clop Lotion FAQs

What is Clop Lotion used for?
Clop Lotion is commonly used for Clop Lotion is used in the treatment of skin infections. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Clop Lotion?
Clop Lotion contains Clobetasol (0.05%w/v). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Clop Lotion?
Clean and dry the affected area, then apply a thin layer and rub it in gently. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Clop Lotion work?
Clop Lotion is a steroid.
Is Clop Lotion a prescription medicine?
Yes. Clop Lotion is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Clop Lotion?
The side effects reported most often with Clop are Burning or stinging, Thinning of the skin, Stretch marks, Acne, Change in skin colour. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Clop Lotion be taken during pregnancy?
Clop Lotion may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Clop.
Can I drink alcohol while taking Clop Lotion?
No significant interaction with alcohol is expected.
What if I miss a dose of Clop Lotion?
Apply it as soon as you remember.
Is Clop Lotion habit forming?
No. Clop Lotion is not known to be habit forming when taken as prescribed.
How much does Clop Lotion cost on PingMeDoc Pharmacy?
Clop Lotion starts at ₹85 (MRP ₹89) on PingMeDoc Pharmacy. Available in lotion 0.05%w/v 20ML. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Clop Lotion?
Clop Lotion is manufactured by ZYDUS HEALTHCARE PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Clop Lotion delivered?
Clop Lotion is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Clop Lotion, Quick facts

Salt
Clobetasol (0.05%w/v)
Form
lotion
Best price
₹85 (₹4.23 per ml)
MRP
₹89
Prescription
Required (Rx)
Brand
ZYDUS HEALTHCARE PHARMA
Manufacturer
ZYDUS HEALTHCARE PHARMA
Therapeutic class
Topical corticosteroid
Drug class
Corticosteroid / calcineurin inhibitor
Habit forming
No
Variants
lotion 0.05%w/v 20ML
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Clop Lotion.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.