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Prescription requiredProcter & Gamble Health LtdAnalgesic and antipyretic, Cough and cold preparation and Anti-allergic

Cosome Msr Tablet

Paracetamol (500mg) + Phenylephrine (10mg) + Chlorpheniramine (2mg)

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Same composition, in stock now. Check with your doctor or pharmacist before you switch.

  • Sinarest Syrup₹136View

Cosome Msr Tablet is used for this medicine is used in the treatment of fever, headache, body ache, mild to moderate pain, cough, chest congestion, common cold symptoms, allergic rhinitis, hives and skin allergy, itching and allergic asthma.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Paracetamol (500mg) + Phenylephrine (10mg) + Chlorpheniramine (2mg)
Available variants: tablet 500mg + 10mg + 2mg 10`S
Best price: ₹40 (₹4.01 per tablet)
MRP: ₹42
Prescription: Required
Manufacturer: P&G

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Cosome Msr Tablet

Cosome Msr Tablet contains Paracetamol (500mg) + Phenylephrine (10mg) + Chlorpheniramine (2mg). It belongs to the Para-aminophenol derivative, Expectorant / mucolytic / bronchodilator and Antihistamine / leukotriene antagonist class of medicines.

Uses of Cosome Msr Tablet

  • This medicine is used in the treatment of fever
  • headache
  • body ache
  • mild to moderate pain
  • cough
  • chest congestion
  • common cold symptoms
  • allergic rhinitis
  • hives and skin allergy
  • itching and allergic asthma.

Key benefits

  • The first choice for fever and everyday pain
  • Gentle on the stomach
  • unlike anti-inflammatory painkillers
  • Eases a chesty cough
  • Helps clear congestion
  • Fast relief of sneezing
  • running nose and itching
  • Non-sedating options are available
  • Usually taken once a day

How Cosome Msr Tablet works

Cosome MSR Tablet is a combination of three medicines:.

How to take Cosome Msr Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cosome MSR Tablet may be taken with or without food, but it is better to take it at a fixed time.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause severe and sometimes fatal liver damage, often with no symptoms at all for the first day. It can cause vomiting, severe drowsiness, a racing heart and, with codeine, dangerously slow breathing. It can cause severe drowsiness, a fast heartbeat, confusion and, in children, agitation and fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Cosome Msr Tablet

Most side effects of Cosome Msr are mild and settle as the body adjusts. Reported side effects include:

  • Nausea
  • Rash
  • Vomiting
  • Stomach upset
  • Drowsiness
  • Tremor
  • Fast heartbeat
  • Dry mouth
  • Headache
  • Tiredness

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Cosome Msr Tablet

PregnancyCosome MSR Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
BreastfeedingCosome MSR Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
AlcoholIt is unsafe to consume alcohol with Cosome MSR Tablet .
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyCosome MSR Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Cosome MSR Tablet may not be needed in these patients. Please consult your doctor.Use of Cosome MSR Tablet may cause excessive sleepiness in patients with end stage kidney disease.
LiverCosome MSR Tablet should be used with caution in patients with liver disease. Dose adjustment of Cosome MSR Tablet may be needed. Please consult your doctor.
Habit formingNo

Warnings and precautions

Never exceed the daily maximum printed on the pack. Paracetamol overdose damages the liver, and the damage can be silent for a day or two before it becomes serious. Check every other medicine you are taking. Paracetamol is in a very large number of cold, flu and pain combinations, and the doses add together. If you drink alcohol regularly, or have liver disease, ask your doctor what daily limit is safe for you. See a doctor if fever lasts more than three days, or pain more than five. See a doctor if a cough lasts more than a week, or comes with fever, breathlessness, chest pain or blood in the sputum. Do not give cough and cold preparations to young children except on a doctor's advice. Do not combine two cough preparations — they frequently contain the same ingredients, and the doses add up. Preparations containing codeine can cause dependence and must be used only for the period your doctor specifies. Older antihistamines cause marked drowsiness — do not drive or operate machinery until you know how this affects you. Tell your doctor promptly about any change in mood, sleep, agitation or unusual thoughts while taking montelukast; this is uncommon but recognised. This relieves the symptoms of an allergy; it does not treat the cause, and it is not a treatment for an acute asthma attack. Seek emergency care for swelling of the lips, tongue or throat, or difficulty breathing.

Do not take Cosome Msr if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe liver disease, except under medical supervision. Codeine-containing preparations are not for children, or for anyone with breathing difficulty. The sedating antihistamines are not suitable for very young children, or for people with glaucoma or an enlarged prostate, without medical advice.

Interactions with other medicines

Regular alcohol use increases the risk of liver injury. Tell your doctor if you are on warfarin — regular high-dose paracetamol can affect it. Sedating ingredients add to the effect of alcohol and sleeping tablets. Decongestants such as phenylephrine and pseudoephedrine can raise blood pressure — tell your doctor if you are hypertensive. Alcohol, sleeping tablets and other sedating medicines add to the drowsiness. Tell your doctor about all cold and cough preparations — many already contain an antihistamine.

How to store Cosome Msr Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Cosome Msr Tablet

Take the lowest dose that works, and leave the stated gap between doses. Seek help immediately after a suspected overdose, even if you feel completely well — treatment works best when it is early. Drink plenty of water — it thins mucus better than any syrup. Steam inhalation helps congestion and costs nothing. Measure the dose with the cup supplied. Taking it at bedtime reduces the impact of any drowsiness. Identify and avoid your triggers where you can — dust, pollen, cold air.

Manufacturer and class

Manufacturer:
P&G
Therapeutic class:
Analgesic and antipyretic, Cough and cold preparation and Anti-allergic
Drug class:
Para-aminophenol derivative, Expectorant / mucolytic / bronchodilator and Antihistamine / leukotriene antagonist

Substitutes for Cosome Msr Tablet

Medicines with the same active ingredient (Paracetamol (500mg) + Phenylephrine (10mg) + Chlorpheniramine (2mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Cosome Msr Tablet
Sinarest SyrupCENTAUR PHARMACEUTICALS LTD`syrup · 75ML₹136240% more
See all substitutes and alternatives

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Cosome Msr Tablet FAQs

What is Cosome Msr Tablet used for?
Cosome Msr Tablet is commonly used for This medicine is used in the treatment of fever, headache, body ache, mild to moderate pain, cough, chest congestion, common cold symptoms, allergic rhinitis, hives and skin allergy, itching and allergic asthma. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Cosome Msr Tablet?
Cosome Msr Tablet contains Paracetamol (500mg) + Phenylephrine (10mg) + Chlorpheniramine (2mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Cosome Msr Tablet?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Cosome Msr Tablet work?
Cosome MSR Tablet is a combination of three medicines:.
Is Cosome Msr Tablet a prescription medicine?
Yes. Cosome Msr Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Cosome Msr Tablet?
The side effects reported most often with Cosome Msr are Nausea, Rash, Vomiting, Stomach upset, Drowsiness. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Cosome Msr Tablet be taken during pregnancy?
Cosome MSR Tablet may be unsafe to use during pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Cosome Msr.
Can I drink alcohol while taking Cosome Msr Tablet?
It is unsafe to consume alcohol with Cosome MSR Tablet .
What if I miss a dose of Cosome Msr Tablet?
Take it as soon as you remember.
Is Cosome Msr Tablet habit forming?
No. Cosome Msr Tablet is not known to be habit forming when taken as prescribed.
How much does Cosome Msr Tablet cost on PingMeDoc Pharmacy?
Cosome Msr Tablet starts at ₹40 (MRP ₹42) on PingMeDoc Pharmacy. Available in tablet 500mg + 10mg + 2mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Cosome Msr Tablet?
Cosome Msr Tablet is manufactured by P&G. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Cosome Msr Tablet delivered?
Cosome Msr Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Cosome Msr Tablet, Quick facts

Salt
Paracetamol (500mg) + Phenylephrine (10mg) + Chlorpheniramine (2mg)
Form
tablet
Best price
₹40 (₹4.01 per tablet)
MRP
₹42
Prescription
Required (Rx)
Schedule
Schedule H
Brand
Procter & Gamble Health Ltd
Manufacturer
P&G
Therapeutic class
Analgesic and antipyretic, Cough and cold preparation and Anti-allergic
Drug class
Para-aminophenol derivative, Expectorant / mucolytic / bronchodilator and Antihistamine / leukotriene antagonist
Habit forming
No
Variants
tablet 500mg + 10mg + 2mg 10`S
Delivery
Standard across India

References

The information on Cosome Msr Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Cosome Msr Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.