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Prescription requiredZydus Healthcare PharmaAnti-diabetic

Dapaglyn Sm 100/500 Tablet

Metformin (500mg) + Dapagliflozin (10mg) + Sitagliptin (100mg)

₹247MRP ₹2605% offIn stock
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Delivered across India in about 3–5 days, Chennai next day. ₹49 delivery, free above ₹999.

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Dapaglyn Sm 100/500 Tablet is used for this medicine is used in the treatment of type 2 diabetes, heart failure and chronic kidney disease.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Metformin (500mg) + Dapagliflozin (10mg) + Sitagliptin (100mg)
Available variants: tablet 500mg + 10mg + 100mg 10`S
Best price: ₹247 (₹24.74 per tablet)
MRP: ₹260
Prescription: Required
Manufacturer: ZYDUS HEALTHCARE PHARMA

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Same salt, lower price

Medicines with the same active ingredient and strength as Dapaglyn Sm 100/500 Tablet.

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Dapaglyn Sm 100/500 Tablet

tablet - 500mg + 10mg + 100mg - 10 S

₹247

₹24.74 per tablet

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Compare all substitutes
Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Dapaglyn Sm 100/500 Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Composition of Dapaglyn Sm 100/500 Tablet

Dapaglyn Sm 100/500 Tablet contains Metformin (500mg) + Dapagliflozin (10mg) + Sitagliptin (100mg). It belongs to the Biguanide, SGLT2 inhibitor / GLP-1 analogue and DPP-4 inhibitor class of medicines.

Uses of Dapaglyn Sm 100/500 Tablet

  • This medicine is used in the treatment of type 2 diabetes
  • heart failure and chronic kidney disease.

Key benefits

  • First-choice medicine for type 2 diabetes
  • Does not usually cause weight gain
  • Low risk of hypoglycaemia when used alone
  • Protects the heart and kidneys as well as lowering sugar
  • Usually causes modest weight loss
  • Weight neutral
  • Usually taken once a day

How Dapaglyn Sm 100/500 Tablet works

Sitacine-Trio Tablet Er is a combination of three antidiabetic medicines. Dapagliflozin increases urinary glucose excretion and reduces blood glucose levels. Metformin decreases the amount of glucose you absorb from your food and the amount of glucose made by the liver. Metformin also increases the bodys response to insulin, a natural substance that controls the amount of glucose in the blood. Sitagliptin helps control blood sugar levels by increasing substances (incretins) in the body that make the pancreas release more insulin. It also signals the liver to stop producing sugar (glucose) when there is too much sugar in the blood.

How to take Dapaglyn Sm 100/500 Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sitalite-DM Tablet Er may be taken with or without food, but it is better to take it at a fixed time.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It can cause dehydration and a fall in blood pressure. It may cause low blood sugar, particularly if you also take other diabetes medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Dapaglyn Sm 100/500 Tablet

Most side effects of Dapaglyn Sm 100/500 are mild and settle as the body adjusts. Reported side effects include:

  • Nausea
  • Loose motions
  • Stomach pain
  • Metallic taste
  • Loss of appetite
  • Flatulence
  • Passing urine more often
  • Thirst
  • Genital itching or thrush
  • Urinary infection
  • Headache
  • Sore throat
  • Blocked or runny nose

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Dapaglyn Sm 100/500 Tablet

PregnancyInformation regarding the use of Sitalite-DM Tablet ER during pregnancy is not available. Please consult your doctor.
BreastfeedingInformation regarding the use of Sitalite-DM Tablet ER during breastfeeding is not available. Please consult your doctor.
AlcoholIt is not known whether it is safe to consume alcohol with Dapadin-Trio Tablet ER. Please consult your doctor.
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyThere is limited information available on the use of Loridapa-Trio Tablet ER in patients with kidney disease. Please consult your doctor.
LiverThere is limited information available on the use of Dapaglyn SM 100/500 Tablet ER in patients with liver disease. Please consult your doctor.
Habit formingNo

Warnings and precautions

Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time. Drink enough water, especially in hot weather or if you have loose motions — this medicine makes you pass more urine. Seek urgent care for nausea with vomiting, stomach pain and deep rapid breathing, even if your sugar reading is normal. Report any pain, tenderness, redness or swelling in the genital area or perineum immediately — this is rare but needs same-day attention. Genital thrush is common; keep the area clean and dry and tell your doctor if it recurs. Stop and see a doctor urgently if you get severe, persistent abdominal pain that spreads to your back, with or without vomiting. Tell your doctor if you develop severe or disabling joint pain. Blisters or peeling of the skin should be reported promptly.

Do not take Dapaglyn Sm 100/500 if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease.

Interactions with other medicines

Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited. Water tablets increase the risk of dehydration and low blood pressure when taken with this. Low blood sugar is more likely when combined with insulin or a sulfonylurea. Low blood sugar is more likely when this is combined with a sulfonylurea or insulin; your doctor may lower that dose.

How to store Dapaglyn Sm 100/500 Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Dapaglyn Sm 100/500 Tablet

Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them. Take it in the morning so the extra urine does not disturb your sleep. Keep up your fluid intake and maintain genital hygiene. Tell any doctor treating you for an acute illness that you take this medicine. It can be taken with or without food, at the same time each day. Keep up your diet and activity — this medicine supports them.

Manufacturer and class

Manufacturer:
ZYDUS HEALTHCARE PHARMA
Therapeutic class:
Anti-diabetic
Drug class:
Biguanide, SGLT2 inhibitor / GLP-1 analogue and DPP-4 inhibitor

Substitutes for Dapaglyn Sm 100/500 Tablet

Medicines with the same active ingredient (Metformin (500mg) + Dapagliflozin (10mg) + Sitagliptin (100mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Dapaglyn Sm 100/500 Tablet
Galitz 100 TabletSAAN LAB LLPtablet · 10`S₹12649% cheaper
Startsita Dm 500 TabletSANZ PHARMACEUTICALStablet · 10`S₹15139% cheaper
Galitz Trio 10/100/500 TabletSAAN LAB LLPtablet · 10`S₹15338% cheaper
Sitoha-D 50/5 TabletDELLtablet · 10`S₹16035% cheaper
Sitadus-Trio 100 mg TabletLIVIDUS PHARMACEUTICALS PVT LTD.`tablet · 10`S₹16035% cheaper
Sitanat Dm 500 TabletNATCOtablet · 10`S₹16932% cheaper
Dapapep Sm 10/100/500 mg TabletLIPPON PHARMAtablet · 10`S₹18625% cheaper
Sitaclass Dm 100/10/500Macleods Pharmaceuticals Pvt Ltd10`S₹19222% cheaper
Dapalex Sm Tablet 10/100/500AJANTA PHARMAtablet · 10`S₹20119% cheaper
Azsita Trio 500 TabletAZKKA PHARMAtablet · 10`S₹2346% cheaper
Dapahenz Sm 500 TabletLARENONtablet · 10`S₹2451% cheaper
Lupisit Dm 10/1000 mg TabletLUPIN LABtablet · 10`S₹2491% more
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Dapaglyn Sm 100/500 Tablet FAQs

What is Dapaglyn Sm 100/500 Tablet used for?
Dapaglyn Sm 100/500 Tablet is commonly used for This medicine is used in the treatment of type 2 diabetes, heart failure and chronic kidney disease. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Dapaglyn Sm 100/500 Tablet?
Dapaglyn Sm 100/500 Tablet contains Metformin (500mg) + Dapagliflozin (10mg) + Sitagliptin (100mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Dapaglyn Sm 100/500 Tablet?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Dapaglyn Sm 100/500 Tablet work?
Sitacine-Trio Tablet Er is a combination of three antidiabetic medicines.
Is Dapaglyn Sm 100/500 Tablet a prescription medicine?
Yes. Dapaglyn Sm 100/500 Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Dapaglyn Sm 100/500 Tablet?
The side effects reported most often with Dapaglyn Sm 100/500 are Nausea, Loose motions, Stomach pain, Metallic taste, Loss of appetite. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Dapaglyn Sm 100/500 Tablet be taken during pregnancy?
Information regarding the use of Sitalite-DM Tablet ER during pregnancy is not available. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Dapaglyn Sm 100/500.
Can I drink alcohol while taking Dapaglyn Sm 100/500 Tablet?
It is not known whether it is safe to consume alcohol with Dapadin-Trio Tablet ER.
What if I miss a dose of Dapaglyn Sm 100/500 Tablet?
Take it as soon as you remember.
Is Dapaglyn Sm 100/500 Tablet habit forming?
No. Dapaglyn Sm 100/500 Tablet is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Dapaglyn Sm 100/500 Tablet?
Galitz 100 Tablet has the same active ingredient and strength and is listed from ₹126 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Dapaglyn Sm 100/500 Tablet cost on PingMeDoc Pharmacy?
Dapaglyn Sm 100/500 Tablet starts at ₹247 (MRP ₹260) on PingMeDoc Pharmacy. Available in tablet 500mg + 10mg + 100mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Dapaglyn Sm 100/500 Tablet?
Dapaglyn Sm 100/500 Tablet is manufactured by ZYDUS HEALTHCARE PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Dapaglyn Sm 100/500 Tablet delivered?
Dapaglyn Sm 100/500 Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Dapaglyn Sm 100/500 Tablet, Quick facts

Salt
Metformin (500mg) + Dapagliflozin (10mg) + Sitagliptin (100mg)
Form
tablet
Best price
₹247 (₹24.74 per tablet)
MRP
₹260
Prescription
Required (Rx)
Schedule
Schedule H
Brand
ZYDUS HEALTHCARE PHARMA
Manufacturer
ZYDUS HEALTHCARE PHARMA
Therapeutic class
Anti-diabetic
Drug class
Biguanide, SGLT2 inhibitor / GLP-1 analogue and DPP-4 inhibitor
Habit forming
No
Variants
tablet 500mg + 10mg + 100mg 10`S
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Dapaglyn Sm 100/500 Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.