Sitaclass Dm 100/10/500

Composition of Sitaclass Dm 100/10/500

Sitaclass Dm 100/10/500 contains Dapagliflozin (10mg) + Metformin (500mg) + Sitagliptin (100mg). It belongs to the SGLT2 inhibitor / GLP-1 analogue, Biguanide and DPP-4 inhibitor class of medicines.

Uses of Sitaclass Dm 100/10/500

Treatment of Type 2 diabetes mellitus

Key benefits

• In Treatment of Type 2 diabetes mellitus Sitaclass DM 100/10/500 Tablet ER is a medicine that helps control high blood glucose (sugar) levels. It helps get rid of extra glucose from the body through urine. Lowering blood glucose levels is an essential part of managing diabetes
• as this reduces the risk of serious complications
• such as kidney damage
• eye damage
• nerve problems
• and loss of limbs. This medicine will reduce the risk of death from cardiovascular disease if you have type 2 diabetes and cardiovascular disease. Taking Sitaclass DM 100/10/500 Tablet ER regularly with proper diet and exercise will help you live a normal
• healthy life. You should keep using it for as long as it is prescribed for a healthy future.

How Sitaclass Dm 100/10/500 works

Sitaclass DM 100/10/500 Tablet ER is a combination of three antidiabetic medicines. Dapagliflozin increases urinary glucose excretion and reduces blood glucose levels. Metformin decreases the amount of glucose you absorb from your food and the amount of glucose made by the liver. Metformin also increases the body's response to insulin, a natural substance that controls the amount of glucose in the blood. Sitagliptin helps control blood sugar levels by increasing substances (incretins) in the body that make the pancreas release more insulin. It also signals the liver to stop producing sugar (glucose) when there is too much sugar in the blood.

How to take Sitaclass Dm 100/10/500

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sitaclass DM 100/10/500 Tablet ER may be taken with or without food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Sitaclass DM 100/10/500 Tablet ER, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause dehydration and a fall in blood pressure. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It may cause low blood sugar, particularly if you also take other diabetes medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Sitaclass Dm 100/10/500

Most side effects of Sitaclass Dm 100/10/500 are mild and settle as the body adjusts. Reported side effects include:

• Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Sitaclass Dm 100/10/500

Warnings and precautions

Drink enough water, especially in hot weather or if you have loose motions — this medicine makes you pass more urine. Seek urgent care for nausea with vomiting, stomach pain and deep rapid breathing, even if your sugar reading is normal. Report any pain, tenderness, redness or swelling in the genital area or perineum immediately — this is rare but needs same-day attention. Genital thrush is common; keep the area clean and dry and tell your doctor if it recurs. Stomach upset is common in the first two weeks and usually settles; taking it with food helps. Tell your doctor before any surgery or a scan that uses contrast dye — this medicine is usually stopped for a short time around them. Stop and seek urgent care if you develop deep rapid breathing, severe weakness, muscle pain or vomiting with cold clammy skin. This is rare but serious. Long-term use can lower vitamin B12, so your doctor may check it from time to time. Stop and see a doctor urgently if you get severe, persistent abdominal pain that spreads to your back, with or without vomiting. Tell your doctor if you develop severe or disabling joint pain. Blisters or peeling of the skin should be reported promptly.

Do not take Sitaclass Dm 100/10/500 if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Water tablets increase the risk of dehydration and low blood pressure when taken with this. Low blood sugar is more likely when combined with insulin or a sulfonylurea. Tell your doctor about water tablets, steroids, and any contrast dye scan. Alcohol increases the risk of the rare acid build-up and should be limited. Low blood sugar is more likely when this is combined with a sulfonylurea or insulin; your doctor may lower that dose.

How to store Sitaclass Dm 100/10/500

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Sitaclass Dm 100/10/500

Your doctor will monitor your blood sugar levels and kidney function regularly while you are taking this medication. Hypoglycemia (low blood sugar level) may occur when Sitaclass DM 100/10/500 Tablet ER is taken along with other antidiabetic medicines, alcohol, or when delaying/skipping a meal. Check your blood sugar levels and have a snack/sugar source for immediate relief. If you get unusually thirsty, pass urine more frequently, or feel tired, let your doctor know. These are signs that there is too much sugar in your blood, and your dose may need adjusting. Lifestyle changes, like a low-fat and salt diet, exercise, not smoking, and cutting down on the amount of alcohol you normally drink, may help this medicine work better.

Manufacturer and class

Manufacturer:

MACLEODS PHARMACEUTICALS LTD

Therapeutic class:

ANTI DIABETIC

Drug class:

SGLT2 inhibitor / GLP-1 analogue, Biguanide and DPP-4 inhibitor