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Prescription requiredPfizer LtdCorticosteroid

Depo Medrol 40 mg Injection 2 ml

Methylprednisolone (40mg)

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Depo Medrol 40 mg Injection 2 ml is used for depo-Medrol 40 mg/ml Injection is used in the treatment of severe allergic reactions, allergic conditions, asthma, rheumatic disorder, skin disorders, eye disorders and nephrotic syndrome.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Methylprednisolone (40mg)
Available variants: injection 40 mg / 2 ml 2ML
Best price: ₹71 (₹35.27 per ml)
MRP: ₹74
Prescription: Required
Manufacturer: PFIZER LTD`

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Depo Medrol 40 mg Injection 2 ml

Depo Medrol 40 mg Injection 2 ml contains Methylprednisolone (40mg). It belongs to the Systemic corticosteroid class of medicines.

Uses of Depo Medrol 40 mg Injection 2 ml

  • Depo-Medrol 40 mg/ml Injection is used in the treatment of severe allergic reactions
  • allergic conditions
  • asthma
  • rheumatic disorder
  • skin disorders
  • eye disorders and nephrotic syndrome.

Key benefits

  • Fast and powerful control of inflammation
  • Life-saving in severe allergic and autoimmune disease

How Depo Medrol 40 mg Injection 2 ml works

Depo-Medrol 40 mg/ml Injection is a steroid which works by blocking the production of certain chemical messengers in the body that cause inflammation (redness and swelling) and allergies.

How to take Depo Medrol 40 mg Injection 2 ml

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause weight gain, high blood sugar, bone thinning and suppression of the body's own steroid production when it is taken over a prolonged period. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Depo Medrol 40 mg Injection 2 ml

Most side effects of Depo Medrol are mild and settle as the body adjusts. Reported side effects include:

  • Skin thinning Diabetes Injection site reactions (pain
  • swelling
  • redness) Reduction in bone density Weight gain Mood changes Stomach upset Behavioural changes

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Depo Medrol 40 mg Injection 2 ml

PregnancyDepo-Medrol 40 mg/ml Injection may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
BreastfeedingDepo-Medrol 40 mg/ml Injection is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
AlcoholInteraction with alcohol is unknown. Please consult your doctor.
DrivingNot expected to affect your ability to drive.
KidneyDepo-Medrol 40 mg/ml Injection is safe to use in patients with kidney disease. No dose adjustment of Depo-Medrol 40 mg/ml Injection is recommended.<br>However, talk to your doctor if you have any underlying kidney disease.
LiverThere is limited information available on the use of Depo-Medrol 40 mg/ml Injection in patients with liver disease. Please consult your doctor.
Habit formingNo

Warnings and precautions

Never stop a course of more than a few days suddenly. Your body stops making its own steroid while you take these, and abrupt withdrawal can cause a dangerous collapse. Your doctor will taper the dose. Tell any doctor treating you that you take steroids, and say so urgently if you develop a serious infection, injury or need surgery — you may need a higher dose to cope. Steroids raise blood sugar. If you have diabetes, monitor it more closely during a course. Long-term use thins bones, raises the risk of infection, cataract and glaucoma. Your doctor will monitor and may add bone protection. Chickenpox and measles can be severe in people on steroids — seek advice promptly after any contact.

Do not take Depo Medrol if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an untreated systemic infection, except where the steroid is part of the treatment.

Interactions with other medicines

Anti-inflammatory painkillers together with steroids markedly raise the risk of stomach bleeding. Live vaccines are generally avoided during significant steroid treatment.

How to store Depo Medrol 40 mg Injection 2 ml

Store as printed on the carton — some injections need refrigeration and must not be frozen. Keep out of the reach of children.

Expert advice for Depo Medrol 40 mg Injection 2 ml

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li><div>Depo-Medrol 40 mg/ml Injection  helps treat inflammation, severe allergies, flare-ups of ongoing illnesses, and many other medical problems that require either reduction of inflammation or suppression of the immune system.</div></li> <li>Don't use it more often or for longer than advised by your doctor.</li> <li><div>Take it with food to avoid an upset stomach.</div></li> <li><div>Depo-Medrol 40 mg/ml Injection can make it harder for you to fight off infections. Notify your doctor if you have any signs of infection such as a fever or sore throat.</div></li> <li>Side effects such as mood changes or stomach problems can happen when you start taking Depo-Medrol 40 mg/ml Injection . Inform your doctor if this bothers you.</li> <li>Do not stop taking Depo-Medrol 40 mg/ml Injection suddenly without talking to your doctor first as it may cause worsening of symptoms.</li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:
PFIZER LTD`
Therapeutic class:
Corticosteroid
Drug class:
Systemic corticosteroid

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Depo Medrol 40 mg Injection 2 ml FAQs

What is Depo Medrol 40 mg Injection 2 ml used for?
Depo Medrol 40 mg Injection 2 ml is commonly used for Depo-Medrol 40 mg/ml Injection is used in the treatment of severe allergic reactions, allergic conditions, asthma, rheumatic disorder, skin disorders, eye disorders and nephrotic syndrome. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Depo Medrol 40 mg Injection 2 ml?
Depo Medrol 40 mg Injection 2 ml contains Methylprednisolone (40mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Depo Medrol 40 mg Injection 2 ml?
Your doctor or nurse will give you this medicine. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Depo Medrol 40 mg Injection 2 ml work?
Depo-Medrol 40 mg/ml Injection is a steroid which works by blocking the production of certain chemical messengers in the body that cause inflammation (redness and swelling) and allergies.
Is Depo Medrol 40 mg Injection 2 ml a prescription medicine?
Yes. Depo Medrol 40 mg Injection 2 ml is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Depo Medrol 40 mg Injection 2 ml?
The side effects reported most often with Depo Medrol are Skin thinning Diabetes Injection site reactions (pain, swelling, redness) Reduction in bone density Weight gain Mood changes Stomach upset Behavioural changes. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Depo Medrol 40 mg Injection 2 ml be taken during pregnancy?
Depo-Medrol 40 mg/ml Injection may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Depo Medrol.
Can I drink alcohol while taking Depo Medrol 40 mg Injection 2 ml?
Interaction with alcohol is unknown.
What if I miss a dose of Depo Medrol 40 mg Injection 2 ml?
Take it as soon as you remember.
Is Depo Medrol 40 mg Injection 2 ml habit forming?
No. Depo Medrol 40 mg Injection 2 ml is not known to be habit forming when taken as prescribed.
How much does Depo Medrol 40 mg Injection 2 ml cost on PingMeDoc Pharmacy?
Depo Medrol 40 mg Injection 2 ml starts at ₹71 (MRP ₹74) on PingMeDoc Pharmacy. Available in injection 40 mg / 2 ml 2ML. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Depo Medrol 40 mg Injection 2 ml?
Depo Medrol 40 mg Injection 2 ml is manufactured by PFIZER LTD`. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Depo Medrol 40 mg Injection 2 ml delivered?
Depo Medrol 40 mg Injection 2 ml is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Depo Medrol 40 mg Injection 2 ml, Quick facts

Salt
Methylprednisolone (40mg)
Form
injection
Best price
₹71 (₹35.27 per ml)
MRP
₹74
Prescription
Required (Rx)
Schedule
Schedule H
Brand
Pfizer Ltd
Manufacturer
PFIZER LTD`
Therapeutic class
Corticosteroid
Drug class
Systemic corticosteroid
Habit forming
No
Variants
injection 40 mg / 2 ml 2ML
Delivery
Standard across India

References

The information on Depo Medrol 40 mg Injection 2 ml is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Depo Medrol 40 mg Injection 2 ml.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.