Divalvis OD 250 Tablet

Composition of Divalvis OD 250 Tablet

Divalvis OD 250 Tablet contains Divalproex sodium 250 mg (extended-release/OD) tablet. It belongs to the Valproate (antiepileptic; GABA enhancer) class of medicines.

Uses of Divalvis OD 250 Tablet

• Treatment of epilepsy/seizure disorders
• acute manic episodes in bipolar disorder
• prevention of migraine headaches (prophylaxis)

Key benefits

• Controls seizures
• Helps manage acute mania in bipolar disorder
• Prevents migraine attacks
• Stabilizes mood
• Reduces abnormal electrical activity in the brain

How Divalvis OD 250 Tablet works

Divalproex sodium dissociates to valproate in the body. Valproate increases brain GABA activity and modulates sodium and calcium channels, stabilizing neuronal firing and reducing abnormal electrical activity.

How to take Divalvis OD 250 Tablet

Take by mouth exactly as prescribed, usually once daily (OD). Swallow the tablet whole; do not crush, chew or split (extended-release). Can be taken with food to reduce stomach upset; take at the same time each day.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause deep unconsciousness, slowed breathing and dangerous heart rhythm disturbance. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Divalvis OD 250 Tablet

Most side effects of Divalvis OD are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• abdominal pain
• diarrhea
• indigestion
• dizziness
• drowsiness
• tremor
• headache
• weight gain
• hair loss
• increased appetite

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Divalvis OD 250 Tablet

Warnings and precautions

Prescription medicine. Risk of serious liver injury (especially in the first 6 months), pancreatitis, and hyperammonemic encephalopathy—seek urgent care for severe abdominal pain, persistent vomiting, jaundice, confusion, or unusual lethargy. Can cause thrombocytopenia/bleeding; periodic liver function tests and blood counts may be needed. May cause sedation—avoid driving if affected. Do not stop suddenly without medical advice (risk of seizures). Not recommended in pregnancy due to high risk of major birth defects and impaired neurodevelopment; effective contraception is advised for women of childbearing potential. Use caution in liver disease, urea cycle disorders, and mitochondrial disorders (e.g., POLG mutations).

Do not take Divalvis OD if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Valproate-containing medicines are contraindicated in pregnancy for epilepsy unless no alternative exists, and in all women of childbearing potential without a pregnancy prevention programme. Several are not suitable in significant liver disease.

Interactions with other medicines

Carbamazepine, phenytoin, phenobarbital/primidone, lamotrigine (increased risk of serious rash), topiramate (hyperammonemia), warfarin/anticoagulants (bleeding risk), aspirin/salicylates (increased valproate levels/bleeding), benzodiazepines and other CNS depressants, antipsychotics, alcohol

How to store Divalvis OD 250 Tablet

Store below 25°C in a dry place, protected from light and moisture. Keep in original blister pack and out of reach of children.

Expert advice for Divalvis OD 250 Tablet

Take it at the same times every day; a missed dose is a common trigger for a seizure. Keep a seizure diary and take it to your appointments. Tell your doctor before planning a pregnancy — the regimen may need to be changed well in advance. Do not drive until you meet the legal seizure-free period and your doctor agrees.

Manufacturer and class

Manufacturer:

INFIVIS LIFE CARE

Therapeutic class:

Antiepileptic / Mood stabilizer

Drug class:

Valproate (antiepileptic; GABA enhancer)