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Alkem Lab - Tablet - 15 S
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Donepezil (5mg) + Memantine (5mg)
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Same composition, in stock now. Check with your doctor or pharmacist before you switch.
Donep-M Forte Tablet is used for donep-M Tablet is used in the treatment of Alzheimer's disease.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Donep-M Forte Tablet contains Donepezil (5mg) + Memantine (5mg). It belongs to the Anti-dementia / anti-parkinsonian agent class of medicines.
Donep-M Tablet is used in the treatment of Alzheimer's disease.
Donep-M Tablet is a combination of two medicines: Donepezil and Memantine which treat Alzheimer’s disease. Donepezil is a cholinesterase inhibitor while Memantine is an NMDA inhibitor. Together, they balance the levels of chemical messengers in the brain and help in the transmission of nerve signals.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Donep-M Tablet may be taken with or without food, but it is better to take it at a fixed time.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause severe confusion, abnormal movements, a very slow pulse and collapse. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Donep-M Forte are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Donep-M Tablet may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | No information is available on the use of Donep-M Tablet during lactation. Please consult your doctor. |
| Alcohol | Interaction with alcohol is unknown. Please consult your doctor. |
| Driving | Do not drive or operate machinery while taking this medicine. |
| Kidney | Donep-M Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Donep-M Tablet may not be needed in these patients. Please consult your doctor. |
| Liver | Donep-M Tablet should be used with caution in patients with liver disease. Dose adjustment of Donep-M Tablet may be needed. Please consult your doctor. |
| Habit forming | No |
Never stop a Parkinson's medicine suddenly — this can cause a severe and dangerous deterioration. Dose timing matters a great deal in Parkinson's disease. Take it at exactly the times prescribed. Report sudden daytime sleep attacks, hallucinations, or new gambling, spending or other impulsive behaviour — these are recognised effects and the dose may need review. Rise slowly from sitting or lying; a drop in blood pressure on standing is common.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Your doctor will assess suitability if you have heart, eye or psychiatric conditions.
Anti-emetics such as metoclopramide and some antipsychotics can worsen Parkinson's symptoms. High-protein meals can reduce the absorption of levodopa — ask your doctor about timing.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>Donep M Tablet is used for the symptomatic treatment of alzheimer's disease. It does not cure alzheimer's, but may help with brain function and doing daily activities.</li> <li>Take it with food to avoid an upset stomach and drink plenty of fluids to keep yourself hydrated while taking this medicine.</li> <li>Monitor your body weight regularly as both Donep M Tablet and alzheimer's disease can cause weight loss.</li> <li>Don't drive or do anything that requires mental focus until you know how it affects you.</li> <li>Inform your doctor if you have a history of seizures as it may raise the chances of seizure if you had them in the past.</li> <li>It may cause stomach ulcers, specially if you are also taking medications for inflammation or pain. Talk to your doctor if you vomit blood or have black colored stools.</li></ul></div></div></div></div></div></div>
Medicines with the same active ingredient (Donepezil (5mg) + Memantine (5mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Donep-M Forte Tablet |
|---|---|---|---|
| Aricep M TabletEISAI INDIA PVT LTD | tablet · 10`S | ₹155 | 6% more |
| Larentine D 5 TabletLARENON | tablet · 10`S | ₹157 | 7% more |

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The information on Donep-M Forte Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.