
8X Cream
Cipla Limited - Cream - 1%W/W - 30 G
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Domperidone (30mg) + Esomeprazole (20mg)
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Esomac D 20 Capsule is used for domperidone is used in the treatment of nausea and vomiting.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Esomac D 20 Capsule contains Domperidone (30mg) + Esomeprazole (20mg). It belongs to the Anti-emetic / prokinetic and Proton pump inhibitor class of medicines.
Domperidone is used in the treatment of nausea and vomiting.
<div class="DrugOverview__tag___fooLQ">Common</div><ul class="DrugOverview__list___1HjxR DrugOverview__content___22ZBX"><li>Nausea</li><li>Headache</li><li>Abdominal pain</li><li>Constipation</li><li>Flatulence</li><li>Diarrhea</li><li>Dizziness</li><li>Dryness in mouth</li></ul>
<div class="DrugOverview__tag___fooLQ">Common</div><ul class="DrugOverview__list___1HjxR DrugOverview__content___22ZBX"><li>Headache</li><li>Dryness in mouth</li><li>Stomach pain</li><li>Diarrhea</li></ul>
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause drowsiness, disorientation and abnormal muscle movements. It may cause confusion, blurred vision, sweating and a fast heartbeat. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Esomac D are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Esomac D 20 Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor. |
|---|---|
| Breastfeeding | Esomac D 20 Capsule is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby. |
| Alcohol | Caution is advised when consuming alcohol with Esomac D 20 Capsule . Please consult your doctor. |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Esonix-DSR Capsule should be used with caution in patients with kidney disease. Dose adjustment of Esonix-DSR Capsule may be needed. Please consult your doctor. |
| Liver | Esonix-DSR Capsule should be used with caution in patients with liver disease. Dose adjustment of Esonix-DSR Capsule may be needed. Please consult your doctor.Use of Esonix-DSR Capsule is not recommended in patients with moderate and severe liver disease. |
| Habit forming | No |
Use it for the shortest period that works. These medicines are not intended for long-term daily use. Report any unusual muscle stiffness, tremor, restlessness or uncontrolled movements of the face or limbs at once — stop and contact your doctor. Tell your doctor if you have a heart rhythm problem; some of this group affect the heart's electrical timing. Persistent vomiting needs a diagnosis. Do not keep suppressing it without seeing a doctor, especially with abdominal pain, fever or blood. Take it on an empty stomach, about half an hour to an hour before your first meal — this is when the acid pumps are most active and the medicine works best. Long-term use has been linked to low magnesium and low vitamin B12, and to a higher risk of bone fracture. Review the need with your doctor rather than continuing indefinitely. Tell your doctor if acidity comes with difficulty swallowing, vomiting, weight loss, or black stools — these need investigation, not a longer course. Do not stop a long course abruptly; acid can rebound. Your doctor will taper it.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with bleeding, blockage or perforation of the gut, or with certain heart rhythm disorders.
Antifungals, some antibiotics and heart-rhythm medicines increase the risk of rhythm problems when combined. Adds to the drowsiness of alcohol and sedatives. Reduces the absorption of some antifungals, iron and certain HIV medicines. Tell your doctor if you take clopidogrel, methotrexate or a blood thinner.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
<div class="style__desktop-container___1hcBT"><div><div><div><div><h2 class="ExpertAdviceItem__header___3GJKM">Related to Domperidone</h2><div class="ExpertAdviceItem__content___1Djk2"><ul><li>Domperidone helps relieve nausea and vomiting.</li> <li>It should be taken before meals as per the dose and duration prescribed by your doctor.</li> <li>It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.</li> <li>Avoid consuming alcohol when taking Domperidone as it may cause excessive drowsiness.</li> <li>Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.</li> <li><div>Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.</div></li> <li>Do not take it for longer than 7 days without consulting your doctor.</li></ul></div></div></div></div><div><div><div><h2 class="ExpertAdviceItem__header___3GJKM">Related to Esomeprazole</h2><div class="ExpertAdviceItem__content___1Djk2"><ul><li>Take it one hour before the meal, preferably in the morning.</li> <li>It is a well-tolerated medicine and provides relief for a long time.</li> <li>Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.</li> <li>Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.</li> <li>Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.</li></ul></div></div></div></div></div></div>
Medicines with the same active ingredient (Domperidone (30mg) + Esomeprazole (20mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Esomac D 20 Capsule |
|---|---|---|---|
| Esomefa Dsr Capsule | 10 | ₹123 | 3% cheaper |
| Nexpro Rd 20 CapsuleTorrent Pharmaceuticals Ltd | capsule · 10`S | ₹139 | 10% more |
| Neksium 20 TabletCIPLA LIMITED | tablet · 15`S | ₹142 | 12% more |

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The information on Esomac D 20 Capsule is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.