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Prescription requiredCipla LimitedAnti-emetic and Anti-ulcer agent

Esomac D 20 Capsule

Domperidone (30mg) + Esomeprazole (20mg)

₹127MRP ₹133In stock
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Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.

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Esomac D 20 Capsule is used for domperidone is used in the treatment of nausea and vomiting.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Domperidone (30mg) + Esomeprazole (20mg)
Available variants: capsule 30mg + 20mg 10`S
Best price: ₹127 (₹12.67 per capsule)
MRP: ₹133
Prescription: Required
Manufacturer: CIPLA LIMITED

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Esomac D 20 Capsule

Esomac D 20 Capsule contains Domperidone (30mg) + Esomeprazole (20mg). It belongs to the Anti-emetic / prokinetic and Proton pump inhibitor class of medicines.

Uses of Esomac D 20 Capsule

Domperidone is used in the treatment of nausea and vomiting.

Key benefits

  • Rapid relief of nausea and vomiting
  • Helps bloating and early fullness
  • Powerful and reliable relief of acidity
  • Heals ulcers and reflux damage
  • Usually taken once a day

How Esomac D 20 Capsule works

<div class="DrugOverview__tag___fooLQ">Common</div><ul class="DrugOverview__list___1HjxR DrugOverview__content___22ZBX"><li>Nausea</li><li>Headache</li><li>Abdominal pain</li><li>Constipation</li><li>Flatulence</li><li>Diarrhea</li><li>Dizziness</li><li>Dryness in mouth</li></ul>

How to take Esomac D 20 Capsule

<div class="DrugOverview__tag___fooLQ">Common</div><ul class="DrugOverview__list___1HjxR DrugOverview__content___22ZBX"><li>Headache</li><li>Dryness in mouth</li><li>Stomach pain</li><li>Diarrhea</li></ul>

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause drowsiness, disorientation and abnormal muscle movements. It may cause confusion, blurred vision, sweating and a fast heartbeat. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Esomac D 20 Capsule

Most side effects of Esomac D are mild and settle as the body adjusts. Reported side effects include:

  • Esomeprazole is used in the treatment of gastroesophageal reflux disease (acid reflux) and peptic ulcer disease.

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Esomac D 20 Capsule

PregnancyEsomac D 20 Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
BreastfeedingEsomac D 20 Capsule is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
AlcoholCaution is advised when consuming alcohol with Esomac D 20 Capsule . Please consult your doctor.
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyEsonix-DSR Capsule should be used with caution in patients with kidney disease. Dose adjustment of Esonix-DSR Capsule may be needed. Please consult your doctor.
LiverEsonix-DSR Capsule should be used with caution in patients with liver disease. Dose adjustment of Esonix-DSR Capsule may be needed. Please consult your doctor.Use of Esonix-DSR Capsule is not recommended in patients with moderate and severe liver disease.
Habit formingNo

Warnings and precautions

Use it for the shortest period that works. These medicines are not intended for long-term daily use. Report any unusual muscle stiffness, tremor, restlessness or uncontrolled movements of the face or limbs at once — stop and contact your doctor. Tell your doctor if you have a heart rhythm problem; some of this group affect the heart's electrical timing. Persistent vomiting needs a diagnosis. Do not keep suppressing it without seeing a doctor, especially with abdominal pain, fever or blood. Take it on an empty stomach, about half an hour to an hour before your first meal — this is when the acid pumps are most active and the medicine works best. Long-term use has been linked to low magnesium and low vitamin B12, and to a higher risk of bone fracture. Review the need with your doctor rather than continuing indefinitely. Tell your doctor if acidity comes with difficulty swallowing, vomiting, weight loss, or black stools — these need investigation, not a longer course. Do not stop a long course abruptly; acid can rebound. Your doctor will taper it.

Do not take Esomac D if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with bleeding, blockage or perforation of the gut, or with certain heart rhythm disorders.

Interactions with other medicines

Antifungals, some antibiotics and heart-rhythm medicines increase the risk of rhythm problems when combined. Adds to the drowsiness of alcohol and sedatives. Reduces the absorption of some antifungals, iron and certain HIV medicines. Tell your doctor if you take clopidogrel, methotrexate or a blood thinner.

How to store Esomac D 20 Capsule

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Esomac D 20 Capsule

<div class="style__desktop-container___1hcBT"><div><div><div><div><h2 class="ExpertAdviceItem__header___3GJKM">Related to Domperidone</h2><div class="ExpertAdviceItem__content___1Djk2"><ul><li>Domperidone helps relieve nausea and vomiting.</li> <li>It should be taken before meals as per the dose and duration prescribed by your doctor.</li> <li>It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.</li> <li>Avoid consuming alcohol when taking Domperidone as it may cause excessive drowsiness.</li> <li>Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.</li> <li><div>Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.</div></li> <li>Do not take it for longer than 7 days without consulting your doctor.</li></ul></div></div></div></div><div><div><div><h2 class="ExpertAdviceItem__header___3GJKM">Related to Esomeprazole</h2><div class="ExpertAdviceItem__content___1Djk2"><ul><li>Take it one hour before the meal, preferably in the morning.</li> <li>It is a well-tolerated medicine and provides relief for a long time.</li> <li>Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.</li> <li>Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.</li> <li>Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.</li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:
CIPLA LIMITED
Therapeutic class:
Anti-emetic and Anti-ulcer agent
Drug class:
Anti-emetic / prokinetic and Proton pump inhibitor

Substitutes for Esomac D 20 Capsule

Medicines with the same active ingredient (Domperidone (30mg) + Esomeprazole (20mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Esomac D 20 Capsule
Esomefa Dsr Capsule10₹1233% cheaper
Nexpro Rd 20 CapsuleTorrent Pharmaceuticals Ltdcapsule · 10`S₹13910% more
Neksium 20 TabletCIPLA LIMITEDtablet · 15`S₹14212% more
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Esomac D 20 Capsule FAQs

What is Esomac D 20 Capsule used for?
Esomac D 20 Capsule is commonly used for Domperidone is used in the treatment of nausea and vomiting. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Esomac D 20 Capsule?
Esomac D 20 Capsule contains Domperidone (30mg) + Esomeprazole (20mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Esomac D 20 Capsule?
<div class="DrugOverview__tag___fooLQ">Common</div><ul class="DrugOverview__list___1HjxR DrugOverview__content___22ZBX"><li>Headache</li><li>Dryness in mouth</li><li>Stomach pain</li><li>Diarrhea</li></ul> Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Esomac D 20 Capsule work?
<div class="DrugOverview__tag___fooLQ">Common</div><ul class="DrugOverview__list___1HjxR DrugOverview__content___22ZBX"><li>Nausea</li><li>Headache</li><li>Abdominal...
Is Esomac D 20 Capsule a prescription medicine?
Yes. Esomac D 20 Capsule is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Esomac D 20 Capsule?
The side effects reported most often with Esomac D are Esomeprazole is used in the treatment of gastroesophageal reflux disease (acid reflux) and peptic ulcer disease.. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Esomac D 20 Capsule be taken during pregnancy?
Esomac D 20 Capsule may be unsafe to use during pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Esomac D.
Can I drink alcohol while taking Esomac D 20 Capsule?
Caution is advised when consuming alcohol with Esomac D 20 Capsule .
What if I miss a dose of Esomac D 20 Capsule?
Take it as soon as you remember.
Is Esomac D 20 Capsule habit forming?
No. Esomac D 20 Capsule is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Esomac D 20 Capsule?
Esomefa Dsr Capsule has the same active ingredient and strength and is listed from ₹123 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Esomac D 20 Capsule cost on PingMeDoc Pharmacy?
Esomac D 20 Capsule starts at ₹127 (MRP ₹133) on PingMeDoc Pharmacy. Available in capsule 30mg + 20mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Esomac D 20 Capsule?
Esomac D 20 Capsule is manufactured by CIPLA LIMITED. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Esomac D 20 Capsule delivered?
Esomac D 20 Capsule is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Esomac D 20 Capsule, Quick facts

Salt
Domperidone (30mg) + Esomeprazole (20mg)
Form
capsule
Best price
₹127 (₹12.67 per capsule)
MRP
₹133
Prescription
Required (Rx)
Schedule
Schedule H
Brand
CIPLA LIMITED
Manufacturer
CIPLA LIMITED
Therapeutic class
Anti-emetic and Anti-ulcer agent
Drug class
Anti-emetic / prokinetic and Proton pump inhibitor
Habit forming
No
Variants
capsule 30mg + 20mg 10`S
Delivery
Standard across India

References

The information on Esomac D 20 Capsule is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Esomac D 20 Capsule.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.