Actibile 150MG Tab
Zydus Healthcare Pharma - Tablet - 150 mg - 10 S
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Espra Xn Tablet
Esomeprazole (20mg) + Naproxen (375mg)
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Espra Xn Tablet is used for espra XN Tablet is used for pain relief.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Licensed pharmacyPharmacist-verified order
Key details
Salt: Esomeprazole (20mg) + Naproxen (375mg)
Available variants: tablet 20mg + 375mg 10`S
Best price: ₹89 (₹8.91 per tablet)
MRP: ₹94
Prescription: Required
Manufacturer: ZYDUS HEALTHCARE PHARMA
Ordering notes
Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Espra Xn Tablet in Bangladesh
55 brands registered in Bangladesh with the same salt, strength and form.
- Anaflex MaxAdvanced Chemical Industries PLC.
- Annova Plus Tablet 375/20Beacon Pharmaceuticals PLC
- DemovoDelta Pharma PLC.
- DinovoBeximco Pharmaceuticals Ltd.
- Duofix 375OSL Pharma Ltd.
- Emaprox 375Globe Pharmaceuticals Ltd.
- Enar 375Medicon Pharmaceuticals Ltd.
- Epizol-N 375Nipa Pharmaceuticals Ltd.
- Eso-PlusAsiatic Laboratories Ltd.
- Esona 375/20Navana Pharmaceuticals Ltd.
- EsoxenNovatek Pharmaceuticals Ltd.
- Exmiv 375MST Pharma and Healthcare Ltd.
Show all 55 brandsShow fewer
- InflectKemiko Pharmaceuticals Ltd.
- Nameso 375Opsonin Pharma Limited
- Napexa 375/20Unimed Unihealth Pharmaceuticals Ltd.
- Napgin Plus-375Biopharma Ltd.
- Napier PlusConcord Pharmaceuticals Ltd.
- Napren ES 375Alco Pharma Limited
- Napro-A PlusThe ACME Laboratories Ltd.
- Naproflex 375Somatec Pharmaceuticals Ltd.
- Naprogard 375Novelta Bestway Pharmaceuticals Ltd.
- Naprohil 375 PlusGoodman Pharmaceuticals Ltd
- Napronex 375/20Apex Pharma Ltd.
- Napronil Plus 375Pharmasia Ltd.
- Naprotec 375Sharif Pharmaceuticals Ltd.
- Naprox Plus 375Eskayef Pharmaceuticals Ltd., Tongi,Gazipur
- Naproxen PlusZenith Pharmaceuticals Ltd.
- Naproxen Plus 375Albion Laboratories Ltd.
- Naproxin Plus 375+20Pharmik Laboratories Ltd.
- Naprozol 375General Pharmaceuticals Ltd.
- NapsecDrug International Ltd.
- Napsec-375 TabletDrug International Ltd., Gopalpur
- NapxonZiska Pharmaceuticals Ltd.
- Nasonaaf 375/20Naafco Pharma PLC.
- NasopainJenphar Bangladesh Ltd.
- Nax Plus-375/20Premier Pharmaceuticals Ltd.
- Naxipraz 375/20Sun Pharmaceutical (Bangladesh) Ltd.
- Naxsil E 375Silco Pharmaceuticlas Ltd.
- NesoAristopharma Limited
- Nesotem 375Team Pharmaceuticals Ltd.
- Novaxen Plus 375Leon Pharmaceuticals Ltd.
- NovoxenOrion Pharma Ltd.
- Nupralgin Plus 375Ibn Sina Pharmaceutical Ind. Ltd.
- NX-PlusOne Pharma Ltd.
- Paincare 375Labaid Pharmaceuticals Ltd.
- ProgesicIncepta Pharmaceuticals Ltd.
- Progut-N 375Popular Pharmaceuticals PLC
- Proxen PlusMonicopharma Limited
- RagoChemist Laboratories Ltd.
- Solivo 375Healthcare Pharmaceuticals Ltd.
- Synaprox Plus 375Rephco Pharmaceuticals Ltd.
- Xenap Plus 375Astra Biopharmaceuticals Ltd.
- Xenapro Plus 375Renata PLC
- Xenmap 375Ethical Drug Ltd.
- XenoleSquare Pharmaceuticals PLC, Pabna
Brand names differ between countries. Ask a pharmacist or your doctor in Bangladesh before switching. We don't sell or ship these brands. Source: Directorate General of Drug Administration, Bangladesh.
Composition of Espra Xn Tablet
Espra Xn Tablet contains Esomeprazole (20mg) + Naproxen (375mg). It belongs to the Proton pump inhibitor and Non-steroidal anti-inflammatory drug class of medicines.
Uses of Espra Xn Tablet
Espra XN Tablet is used for pain relief.
Key benefits
- Powerful and reliable relief of acidity
- Heals ulcers and reflux damage
- Usually taken once a day
- Relieves pain and the swelling that causes it
- Effective in arthritis and injury
How Espra Xn Tablet works
Espra XN Tablet is a combination of two medicines: Naproxen and Esomeprazole which relieve pain. Naproxen is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling). Esomeprazole is a proton-pump inhibitor.which reduces the amount of acid in the stomach and prevents damage to the stomach lining caused by Naproxen.
How to take Espra Xn Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Espra XN Tablet is to be taken with food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
If you take too much
An overdose of this medicine may cause confusion, blurred vision, sweating and a fast heartbeat. It can cause stomach bleeding, kidney failure, drowsiness and fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Espra Xn Tablet
Most side effects of Espra Xn are mild and settle as the body adjusts. Reported side effects include:
- Headache Nausea Vomiting Diarrhea Indigestion Flatulence Stomach pain Flu-like symptoms
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Espra Xn Tablet
| Pregnancy | Espra XN Tablet may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | Espra XN Tablet is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby. |
| Alcohol | Taking a large amount of alcohol can increase acidity and cause acid reflux in the food pipe causing heartburn. This would decrease the effect of this drug and can aggravate your underlying condition. |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Espra XN Tablet should be used with caution in patients with kidney disease. Dose adjustment of Espra XN Tablet may be needed. Please consult your doctor. |
| Liver | Espra XN Tablet should be used with caution in patients with liver disease. Dose adjustment of Espra XN Tablet may be needed. Please consult your doctor. |
| Habit forming | No |
Warnings and precautions
Take it on an empty stomach, about half an hour to an hour before your first meal — this is when the acid pumps are most active and the medicine works best. Long-term use has been linked to low magnesium and low vitamin B12, and to a higher risk of bone fracture. Review the need with your doctor rather than continuing indefinitely. Tell your doctor if acidity comes with difficulty swallowing, vomiting, weight loss, or black stools — these need investigation, not a longer course. Do not stop a long course abruptly; acid can rebound. Your doctor will taper it. Take it with or just after food, and for the shortest time that works. Stop and seek urgent care for black or tarry stools, vomiting blood, or severe stomach pain — this group can cause bleeding from the stomach. Long or high-dose use raises the risk of heart attack, stroke and kidney injury, particularly in older people and those already at risk. Avoid if you are dehydrated or have an illness with vomiting or loose motions — the kidneys are vulnerable then. Must be avoided in the last three months of pregnancy.
Do not take Espra Xn if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy.
Interactions with other medicines
Reduces the absorption of some antifungals, iron and certain HIV medicines. Tell your doctor if you take clopidogrel, methotrexate or a blood thinner. Combining with a blood thinner or aspirin sharply raises the bleeding risk. Reduces the effect of blood pressure medicines and water tablets, and together with them can harm the kidneys. Never take two anti-inflammatory painkillers at the same time.
How to store Espra Xn Tablet
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Expert advice for Espra Xn Tablet
Take it before breakfast, not after a meal. Eat smaller meals, avoid late dinners, raise the head of your bed and avoid smoking — these do as much as the tablet for reflux. Use the lowest dose for the shortest period. If you need a painkiller regularly, see your doctor rather than continuing on your own. Paracetamol is the safer choice for simple fever and headache.
Manufacturer and class
- Manufacturer:
- ZYDUS HEALTHCARE PHARMA
- Therapeutic class:
- prescription
- Drug class:
- Proton pump inhibitor and Non-steroidal anti-inflammatory drug
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Espra Xn Tablet FAQs
What is Espra Xn Tablet used for?
Espra Xn Tablet is commonly used for Espra XN Tablet is used for pain relief. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Espra Xn Tablet?
Espra Xn Tablet contains Esomeprazole (20mg) + Naproxen (375mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Espra Xn Tablet?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Espra Xn Tablet work?
Espra XN Tablet is a combination of two medicines: Naproxen and Esomeprazole which relieve pain.
Is Espra Xn Tablet a prescription medicine?
Yes. Espra Xn Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Espra Xn Tablet?
The side effects reported most often with Espra Xn are Headache
Nausea
Vomiting
Diarrhea
Indigestion
Flatulence
Stomach pain
Flu-like symptoms. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Espra Xn Tablet be taken during pregnancy?
Espra XN Tablet may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Espra Xn.
Can I drink alcohol while taking Espra Xn Tablet?
Taking a large amount of alcohol can increase acidity and cause acid reflux in the food pipe causing heartburn.
What if I miss a dose of Espra Xn Tablet?
Take it as soon as you remember.
Is Espra Xn Tablet habit forming?
No. Espra Xn Tablet is not known to be habit forming when taken as prescribed.
How much does Espra Xn Tablet cost on PingMeDoc Pharmacy?
Espra Xn Tablet starts at ₹89 (MRP ₹94) on PingMeDoc Pharmacy. Available in tablet 20mg + 375mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Espra Xn Tablet?
Espra Xn Tablet is manufactured by ZYDUS HEALTHCARE PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Espra Xn Tablet delivered?
Espra Xn Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.
Espra Xn Tablet, Quick facts
- Salt
- Esomeprazole (20mg) + Naproxen (375mg)
- Form
- tablet
- Best price
- ₹89 (₹8.91 per tablet)
- MRP
- ₹94
- Prescription
- Required (Rx)
- Schedule
- Schedule H
- Brand
- ZYDUS HEALTHCARE PHARMA
- Manufacturer
- ZYDUS HEALTHCARE PHARMA
- Therapeutic class
- prescription
- Drug class
- Proton pump inhibitor and Non-steroidal anti-inflammatory drug
- Habit forming
- No
- Variants
- tablet 20mg + 375mg 10`S
- Delivery
- Standard across India
References
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.
- PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
- CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Espra Xn Tablet.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.