Esula Plus Tablet

Composition of Esula Plus Tablet

Esula Plus Tablet contains Clonazepam (0.25mg) + Escitalopram Oxalate (5mg). It belongs to the Benzodiazepine / sedative-hypnotic and Antidepressant class of medicines.

Uses of Esula Plus Tablet

Treatment of Anxiety disorder

Key benefits

• In Treatment of Anxiety disorder Esula Plus 0.25mg/5mg Tablet stops your brain from releasing the chemicals that make you feel anxious so it can reduce the symptoms of excessive anxiety and worry. It can also reduce feelings of restlessness
• tiredness
• difficulty concentrating
• feeling irritable and sleep problems that often come with Generalised Anxiety Disorder. Esula Plus 0.25mg/5mg Tablet will therefore help you go about your daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping suddenly can cause serious problems.

How Esula Plus Tablet works

Clonazepam and escitalopram have anxiety-lowering and mood-enhancing effects. Clonazepam is a benzodiazepine (BZD) which increases the action of GABA, a chemical messenger that suppresses the abnormal activity of the nerve cells in the brain. Escitalopram is a selective serotonin reuptake inhibitor (SSRI) that increases the levels of serotonin, a chemical messenger that improves mood.

How to take Esula Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esula Plus 0.25mg/5mg Tablet may be taken with or without food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Esula Plus 0.25mg/5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause deep unconsciousness and dangerously slow breathing, particularly with alcohol or an opioid. It can cause fits, dangerous heart rhythm disturbance and coma, and is particularly dangerous with the older tricyclic medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Esula Plus Tablet

Most side effects of Esula Plus are mild and settle as the body adjusts. Reported side effects include:

• Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Esula Plus Tablet

Warnings and precautions

These medicines cause dependence. They are intended for the shortest possible course — usually two to four weeks — and are not a long-term treatment for anxiety or sleeplessness. Never stop a regular course suddenly. Withdrawal can cause severe anxiety, tremor and fits. Your doctor will taper it slowly. Do not drive or operate machinery. Drowsiness and slowed reactions can continue into the next day. Never combine with alcohol or with opioid painkillers — together they can stop your breathing. Older people are far more likely to fall, become confused or have memory problems on these medicines. Several of these are Schedule H1 medicines and must be dispensed against a prescription and entered in the pharmacy register. These medicines take two to four weeks to begin working, and longer for the full effect. Stopping at two weeks because nothing has changed is the commonest mistake. Never stop suddenly. Abrupt withdrawal causes dizziness, electric-shock sensations, irritability and flu-like symptoms — your doctor will reduce the dose gradually. Tell your doctor or go to hospital immediately if thoughts of harming yourself appear or worsen, particularly in the first weeks or after a dose change, and especially in anyone under twenty-five. Seek urgent care for agitation with fever, shivering, a racing heart, muscle twitching or confusion, particularly if more than one medicine affecting serotonin is being taken. Side effects are usually worst in the first fortnight and then settle.

Do not take Esula Plus if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe breathing problems, sleep apnoea, or severe liver disease. Not for anyone with a history of dependence, except under specialist supervision. Must not be combined with a monoamine oxidase inhibitor, or started within the gap your doctor specifies after one.

Interactions with other medicines

Alcohol, opioids, antihistamines, muscle relaxants and other sedatives all deepen the sedation, sometimes fatally. Tramadol, triptans for migraine, linezolid, St John's wort and other antidepressants can together raise serotonin dangerously. Anti-inflammatory painkillers and blood thinners increase the bleeding risk when combined with this group.

How to store Esula Plus Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Esula Plus Tablet

Esula Plus 0.25mg/5mg Tablet is prescribed for the treatment of anxiety disorder. You may feel that Esula Plus 0.25mg/5mg Tablet is not helping you straightaway. This is because it can take a few weeks before you feel the full benefit. It is important that you continue to take it, even if it takes a little while for your condition to improve. If you develop any depressing or suicidal thoughts or ideas, you should let your doctor know about them as soon as possible. You might experience low sexual desire after taking Esula Plus 0.25mg/5mg Tablet. Talk to your doctor if it troubles you.

Manufacturer and class

Manufacturer:

J J HEALTH CARE

Therapeutic class:

NEURO CNS

Drug class:

Benzodiazepine / sedative-hypnotic and Antidepressant