
Alpha Calciras 3C
Ras 3C Pharma - 10 S
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Gliclazide 80 mg + Metformin Hydrochloride 500 mg (tablet)
Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.
This medicine needs a prescription.
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Glycimet 3C 80/500 mg Tablet is used for type 2 diabetes mellitus (to improve blood sugar control when diet and exercise alone are not sufficient).
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Glycimet 3C 80/500 mg Tablet contains Gliclazide 80 mg + Metformin Hydrochloride 500 mg (tablet). It belongs to the Sulfonylurea + Biguanide class of medicines.
Type 2 diabetes mellitus (to improve blood sugar control when diet and exercise alone are not sufficient)
Gliclazide (a sulfonylurea) increases insulin release from the pancreas and helps lower blood glucose. Metformin (a biguanide) decreases glucose production in the liver and improves insulin sensitivity, reducing blood sugar levels.
Oral tablet. Take exactly as prescribed, usually with meals to reduce stomach upset. Swallow whole with water; do not crush/chew unless advised. Regularly monitor blood glucose; do not skip meals to avoid low sugar.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Glycimet 3C 80/500 mg are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult doctor (generally avoid in pregnancy; insulin is preferred) |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | Avoid (increases risk of hypoglycaemia and lactic acidosis with metformin) |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
Risk of hypoglycaemia (higher with missed meals, heavy exercise, alcohol, or other antidiabetics); carry glucose/sugar source. Metformin may rarely cause lactic acidosis—seek urgent care for rapid breathing, severe weakness, abdominal pain, or unusual sleepiness. Use with caution in kidney or liver impairment and in the elderly; kidney function should be assessed periodically. Temporarily stop metformin before/after iodinated contrast procedures and major surgery as advised by doctor. Not for type 1 diabetes or diabetic ketoacidosis.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.
Alcohol, insulin/other antidiabetics (increased hypoglycaemia), beta-blockers (mask hypoglycaemia), corticosteroids (raise glucose), thiazide/loop diuretics (raise glucose), ACE inhibitors (may increase hypoglycaemia), NSAIDs/salicylates (increase sulfonylurea effect), cimetidine (increases metformin levels), iodinated contrast media (lactic acidosis risk), quinolones (glucose disturbances)
Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep out of reach of children.
Take it shortly before a meal, and eat that meal. Check your sugar as often as your doctor has asked, especially when your routine changes. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.
Medicines with the same active ingredient (Gliclazide 80 mg + Metformin Hydrochloride 500 mg (tablet)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Glycimet 3C 80/500 mg Tablet |
|---|---|---|---|
| Glizi-M Tablet | 1X10 | ₹84 | 19% cheaper |
| Glycinorm M 80 mgIPCA LABORATORIES LTD` | TABLET · 15`S | ₹239 | 133% more |

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The information on Glycimet 3C 80/500 mg Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.