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Prescription requiredIpca Laboratories Ltd`DERMA

Hyphoral Cream

Ketoconazole (2% w/v) + Zinc pyrithione (1% w/v)

Currently out of stock

Same composition, in stock now. Check with your doctor or pharmacist before you switch.

  • Ketoff Cream₹105View
  • Ketoya Cream₹106View
  • Ketafung Z Plus Lotion₹215View

Hyphoral Cream is used for treatment of Dandruff Treatment of Fungal skin infections.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Ketoconazole (2% w/v) + Zinc pyrithione (1% w/v)
Available variants: cream 2%w/v + 1%w/v 30GM
Best price: ₹187 (₹6.23 per g)
MRP: ₹197
Prescription: Required
Manufacturer: IPCA LABORATORIES LTD`

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Same salt, lower price

Medicines with the same active ingredient and strength as Hyphoral Cream.

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Hyphoral Cream

cream - 2%w/v + 1%w/v - 30 g

₹187

₹6.23 per g

  • Ketoff Cream

    AAKASH PHARMA PRIVATE LIMITED · cream - 2%w/v + 1%w/v - 20 g · Rx

    ₹105

    ₹5.23 per g

    Save 16%
  • Ketoya Cream

    YAHER PHARMA · cream - 1%w/v + 2%w/v - 20 g · Rx

    ₹106

    ₹5.32 per g

    Save 15%
Compare all substitutes
Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Hyphoral Cream. The medicine inside is the same — the brand name, manufacturer and price are what differ.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Composition of Hyphoral Cream

Hyphoral Cream contains Ketoconazole (2% w/v) + Zinc pyrithione (1% w/v). It belongs to the Antifungal and Hair growth stimulant / anti-dandruff agent class of medicines.

Uses of Hyphoral Cream

Treatment of Dandruff Treatment of Fungal skin infections

Key benefits

  • In Treatment of Dandruff Hyphoral Lotion is used to control dandruff and gives relief from scaly
  • flaky
  • and itchy scalp. It stops the growth of fungus that causes dandruff. Regular use of Hyphoral Lotion protects your scalp and prevents dandruff. Gently massage your scalp with Hyphoral Lotion to loosen flakes. Make sure you complete the full course of treatment. This will ensure that the infection is completely cured and prevent it from returning. In Treatment of Fungal skin infections Hyphoral Lotion is used to treat and control fungal infections like athlete’s foot (infection between toes)
  • jock itch (infection of the groin area)
  • ringworm
  • and other fungal skin infections (candidiasis). Keep using the Hyphoral Lotion for as long as it is prescribed. Show More

How Hyphoral Cream works

Hyphoral Lotion is a combination of two antifungal medicines: Ketoconazole and Zinc pyrithione. It works by destroying the cell membrane of fungi that cause dandruff. Ketoconazole works by breaking down the cell membrane of fungi, effectively killing them, while zinc pyrithione controls fungal growth and reduces irritation, redness, and flaking. Together, they combat fungal infections, soothe the affected area, and prevent recurrence, promoting healthier skin and scalp. Use as directed for best results.

How to take Hyphoral Cream

This medicine is for external use only. Use this medicine in the dose and duration as advised by your doctor. Shake it well and apply to the area evenly.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Hyphoral Lotion, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule.

If you take too much

An overdose of this medicine is unlikely from skin use; swallowing the preparation may cause stomach upset. It can cause a fall in blood pressure and a racing heart when far too much is applied to the skin. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Hyphoral Cream

Most side effects of Hyphoral are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Hyphoral Cream

PregnancyPregnancy SAFE IF PRESCRIBED
BreastfeedingBreast feeding SAFE IF PRESCRIBED
AlcoholAlcohol
DrivingDriving
KidneyKidney
LiverLiver
Habit formingNo

Warnings and precautions

Keep applying for the full period your doctor stated, usually two to four weeks, and for a week or two after the rash has cleared. Stopping when it looks better is why ringworm keeps coming back. Apply a little beyond the visible edge of the patch — the fungus extends further than the redness. Do not use a combination cream containing a steroid on a fungal infection unless a doctor has specifically prescribed it. The steroid calms the redness while the fungus spreads underneath. See a doctor if the rash covers a large area, involves the scalp or nails, or has not improved in two weeks — these usually need tablets as well. Topical minoxidil causes a burst of shedding in the first two to eight weeks. This is the old hair making way for new — it is expected, not a failure. Results take three to six months, and stop when you stop. This is a continuing treatment, not a cure. Finasteride must not be handled or taken by anyone who is pregnant or could become pregnant — it causes birth defects. Do not let a pregnant person handle broken or crushed tablets. Apply topical treatments to a dry scalp, not to hair, and wash your hands afterwards. Tell your doctor about any chest pain, dizziness, rapid heartbeat or sudden weight gain with minoxidil.

Do not take Hyphoral if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. For external use only. Not for use in the eyes. Not for use on inflamed, broken or sunburnt scalp.

Interactions with other medicines

No significant interactions are expected from preparations used on the skin. Avoid applying other scalp products at the same time of day unless advised.

How to store Hyphoral Cream

Store below 30°C, away from direct sunlight. Close the cap tightly after each use. Keep out of the reach of children.

Expert advice for Hyphoral Cream

Do not use this medicine more often or for longer than advised by your doctor. Before each application, wash the affected area with soap and water and dry well. Avoid getting it in the eyes, mouth, or nose. Rinse with cold water if you accidentally get it in these areas. Stop using Hyphoral Lotion and inform your doctor if you notice any irritation or any other skin infection. Inform your doctor if the treated skin area does not improve after 2-4 weeks of treatment.

Manufacturer and class

Manufacturer:
IPCA LABORATORIES LTD`
Therapeutic class:
DERMA
Drug class:
Antifungal and Hair growth stimulant / anti-dandruff agent

Substitutes for Hyphoral Cream

Medicines with the same active ingredient (Ketoconazole (2% w/v) + Zinc pyrithione (1% w/v)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Hyphoral Cream
Ketoff CreamAAKASH PHARMA PRIVATE LIMITEDcream · 20GM₹10544% cheaper
Ketoya CreamYAHER PHARMAcream · 20GM₹10643% cheaper
Ketafung Z Plus LotionEAST WEST PHARMAlotion · 90ML₹21515% more
Unidruff ShampooUNIZAshampoo · 60ML₹22722% more
Derkeeto ShampooScott Edil Pharmacia Ltdshampoo · 100ML₹25134% more
Ketorex ShampooDERMAREX HEALTHCARE (P) LTD.`shampoo · 50ML₹29457% more
Scalpe Plus Ad LotionGLENMARK PHARMACEUTICALSlotion · 75ML₹30563% more
Ketzi LotionINEX MEDICAMENTS PRIVATE LIMITEDlotion · 100ML₹31971% more
Rhizal-Ad Anti Dandruff ShampooTRODAN & CLAIES HEALTHCAREshampoo · 75ML₹32171% more
Kenz Plus LotionKLM LABlotion · 100ML₹32875% more
Kz Plus LotionH & H PHARMACEUTICAL PVT LTDlotion · 75 Ml₹33780% more
Danclear Shampoo 90 mlZYDUS HEALTHCARE PHARMAshampoo · 90ML₹429129% more
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Hyphoral Cream FAQs

What is Hyphoral Cream used for?
Hyphoral Cream is commonly used for Treatment of Dandruff Treatment of Fungal skin infections. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Hyphoral Cream?
Hyphoral Cream contains Ketoconazole (2% w/v) + Zinc pyrithione (1% w/v). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Hyphoral Cream?
This medicine is for external use only. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Hyphoral Cream work?
Hyphoral Lotion is a combination of two antifungal medicines: Ketoconazole and Zinc pyrithione.
Is Hyphoral Cream a prescription medicine?
Yes. Hyphoral Cream is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Hyphoral Cream?
The side effects reported most often with Hyphoral are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Hyphoral Cream be taken during pregnancy?
Pregnancy SAFE IF PRESCRIBED Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Hyphoral.
Can I drink alcohol while taking Hyphoral Cream?
Alcohol
What if I miss a dose of Hyphoral Cream?
If you miss a dose of Hyphoral Lotion, apply it as soon as possible.
Is Hyphoral Cream habit forming?
No. Hyphoral Cream is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Hyphoral Cream?
Ketoff Cream has the same active ingredient and strength and is listed from ₹105 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Hyphoral Cream cost on PingMeDoc Pharmacy?
Hyphoral Cream starts at ₹187 (MRP ₹197) on PingMeDoc Pharmacy. Available in cream 2%w/v + 1%w/v 30GM. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Hyphoral Cream?
Hyphoral Cream is manufactured by IPCA LABORATORIES LTD`. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Hyphoral Cream delivered?
Hyphoral Cream is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Hyphoral Cream, Quick facts

Salt
Ketoconazole (2% w/v) + Zinc pyrithione (1% w/v)
Form
cream
Best price
₹187 (₹6.23 per g)
MRP
₹197
Prescription
Required (Rx)
Brand
IPCA LABORATORIES LTD`
Manufacturer
IPCA LABORATORIES LTD`
Therapeutic class
DERMA
Drug class
Antifungal and Hair growth stimulant / anti-dandruff agent
Habit forming
No
Variants
cream 2%w/v + 1%w/v 30GM
Delivery
Standard across India

References

The information on Hyphoral Cream is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Hyphoral Cream.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.