
Acnesol A Nanogel
Systopic Lab - 15 G
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Isryl M3 is used for treatment of Type 2 diabetes mellitus Hormone replacement therapy.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Treatment of Type 2 diabetes mellitus Hormone replacement therapy
Isryl-M 3 Tablet PR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea that works by increasing the amount of insulin released by the pancreas to lower the blood glucose. Metformin is a biguanide that works by lowering glucose production in the liver, delaying glucose absorption from the intestines, and increasing the body's sensitivity to insulin.
Use it as advised by your doctor or check the label for directions before use. Isryl-M 3 Tablet PR should be taken with or after food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Isryl-M 3 Tablet PR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Taking more Isryl M3 than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.
Most side effects of Isryl M3 are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Pregnancy CONSULT YOUR DOCTOR |
|---|---|
| Breastfeeding | Breast feeding CONSULT YOUR DOCTOR |
| Alcohol | Alcohol UNSAFE |
| Driving | Driving CAUTION |
| Kidney | Kidney UNSAFE |
| Liver | Liver UNSAFE |
| Habit forming | No |
Tell your doctor or pharmacist about every medicine you take, including over-the-counter products, vitamins and herbal or ayurvedic preparations, before starting Isryl M3. Some combinations can change how Isryl M3 works or raise the chance of side effects.
Store Isryl M3 below 30°C in a cool, dry place away from direct sunlight and moisture. Keep the pack tightly closed and out of the reach of children. Do not use it after the expiry date printed on the pack.
You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Isryl-M 3 Tablet PR. Take it with food to lower your chance of having an upset stomach. Monitor your blood sugar level regularly while you are taking this medicine. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic. Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Isryl-M 3 Tablet PR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood. Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

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The information on Isryl M3 is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.