Itzo 200 Capsule

Composition of Itzo 200 Capsule

Itzo 200 Capsule contains Itraconazole 200 mg capsule. It belongs to the Triazole antifungal class of medicines.

Uses of Itzo 200 Capsule

• Treatment of fungal infections such as aspergillosis
• histoplasmosis
• blastomycosis
• onychomycosis (nail fungus)
• tinea infections (ringworm)
• oral/vaginal candidiasis
• and other susceptible systemic or superficial mycoses.

Key benefits

• Treats a wide range of fungal infections
• Effective in nail fungal infections
• Helps in skin ringworm and other dermatophyte infections
• Used for systemic fungal infections under specialist care

How Itzo 200 Capsule works

Itraconazole is a triazole antifungal that inhibits fungal CYP450-dependent 14-α-demethylase, reducing ergosterol synthesis. This disrupts the fungal cell membrane and inhibits growth and survival of the fungus.

How to take Itzo 200 Capsule

Capsule: take exactly as prescribed. Usually taken with food (preferably a full meal) to improve absorption; swallow whole with water. Take at the same time each day and complete the full course; do not stop early even if symptoms improve.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause vomiting, liver injury and heart rhythm disturbance. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Itzo 200 Capsule

Most side effects of Itzo are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• abdominal pain
• diarrhea
• headache
• dizziness
• rash
• liver enzyme increase

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Itzo 200 Capsule

Warnings and precautions

Prescription-only antifungal. Can cause serious liver problems—seek care for jaundice, dark urine, persistent nausea/vomiting. Not recommended in patients with congestive heart failure/ventricular dysfunction (may worsen heart failure). Many significant drug interactions; inform doctor about all medicines. Use caution in liver disease; monitoring of liver function may be required. May cause dizziness—avoid driving if affected.

Do not take Itzo if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with active liver disease, and several are not for use in pregnancy. Itraconazole is not for people with heart failure.

Interactions with other medicines

Strong interactions with drugs affecting CYP3A4. Contraindicated/avoid with: simvastatin/lovastatin, oral midazolam/triazolam, quinidine, dofetilide, cisapride, pimozide, ergot alkaloids. Levels affected by rifampicin/rifabutin, phenytoin, carbamazepine (reduce itraconazole). Increases levels of: warfarin, certain calcium channel blockers, digoxin, cyclosporine/tacrolimus, some benzodiazepines, certain antiarrhythmics. Reduced absorption with antacids, H2 blockers, PPIs—separate dosing and follow medical advice.

How to store Itzo 200 Capsule

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep in original pack and out of reach of children.

Expert advice for Itzo 200 Capsule

Complete the full course, however long. Keep the skin clean and dry, wash clothes and bedding in hot water, and treat family members if they are affected, or reinfection is very likely.

Manufacturer and class

Manufacturer:

DEE GRADIBUS LIFE CARE (P) LTD

Therapeutic class:

Antifungal

Drug class:

Triazole antifungal