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Prescription requiredTorrent Pharmaceuticals LtdAnalgesic and anti-inflammatory

Lefra 20 Tablet

Leflunomide (20mg)

Lefra 20 Tablet is used for this medicine is used in the treatment of pain and swelling, inflammatory arthritis, gout and recovery after injury or surgery.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

₹302₹30.19 per tablet
Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Leflunomide (20mg)
Available variants: tablet tablet 10`S
Best price: ₹302 (₹30.19 per tablet)
Prescription: Required
Manufacturer: TORRENT PHARMACEUTICALS

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Same salt, lower price

Medicines with the same active ingredient and strength as Lefra 20 Tablet.

You are viewing

Lefra 20 Tablet

tablet - 10 S

₹302

₹30.19 per tablet

  • Lefra 10 Tab 10S

    Torrent Pharmaceuticals Ltd · tablet - 10 S · Rx

    ₹155

    ₹15.45 per tablet

    Save 49%
  • Lefutoid 20MG Tab

    LUPIN LAB · tablet - 20 mg - 10 S · Rx

    ₹275

    ₹27.53 per tablet

Compare all substitutes
Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Lefra 20 Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Composition of Lefra 20 Tablet

Lefra 20 Tablet contains Leflunomide (20mg). It belongs to the Enzyme / disease-modifying anti-rheumatic agent class of medicines.

Uses of Lefra 20 Tablet

  • This medicine is used in the treatment of pain and swelling
  • inflammatory arthritis
  • gout and recovery after injury or surgery.

Key benefits

  • Reduces swelling and joint damage over time
  • Improves function in inflammatory disease

How Lefra 20 Tablet works

Leflunomide reduces inflammation and the swelling that comes with injury, surgery or an inflammatory joint disease.

How to take Lefra 20 Tablet

Swallow the tablet whole with a glass of water. Do not chew, crush or break it unless your doctor has told you to. Take it with or after food. Taking it at about the same time each day helps you remember. Follow the dose and the duration written on your prescription.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can seriously suppress the bone marrow and damage the liver. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Lefra 20 Tablet

Most side effects of Lefra are mild and settle as the body adjusts. Reported side effects include:

  • Nausea
  • Stomach upset
  • Loose motions
  • Rash
  • Raised liver enzymes

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Lefra 20 Tablet

PregnancyNot recommended in pregnancy — it may harm the developing baby. Tell your doctor at once if you are or might be pregnant.
BreastfeedingNot recommended while breastfeeding.
AlcoholDo not drink alcohol while taking this medicine.
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyConsult your doctor if you have kidney disease.
LiverConsult your doctor if you have liver disease.
Habit formingNo

Warnings and precautions

Medicines that suppress the immune system need regular blood tests — do not miss them. Report fever, sore throat, mouth ulcers or unusual bruising promptly if you are on an immune-suppressing medicine. Tell your doctor about any infection, and before any vaccination. Methotrexate for arthritis is taken ONCE A WEEK. Taking it daily by mistake is dangerous — check the day on your pack.

Do not take Lefra if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active serious infection, or with severe liver or bone-marrow disease. Several of these medicines must not be used in pregnancy.

Interactions with other medicines

Tell your doctor about all other medicines, especially anti-inflammatory painkillers and antibiotics. Live vaccines are generally avoided while on immune-suppressing treatment.

How to store Lefra 20 Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Lefra 20 Tablet

Keep every monitoring blood test appointment. Carry a note of the medicine and its schedule, especially for weekly dosing.

Manufacturer and class

Manufacturer:
TORRENT PHARMACEUTICALS
Therapeutic class:
Analgesic and anti-inflammatory
Drug class:
Enzyme / disease-modifying anti-rheumatic agent

Substitutes for Lefra 20 Tablet

Medicines with the same active ingredient (Leflunomide (20mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Lefra 20 Tablet
Lefra 10 TabletTorrent Pharmaceuticals Ltdtablet · 10`S₹15549% cheaper
Lefutoid 20 mg TabletLUPIN LABtablet · 10`S₹2759% cheaper
Lefno 20 mg TabletIPCA LABORATORIES LTD`tablet · 10`S₹303same price
See all substitutes and alternatives

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Lefra 20 Tablet FAQs

What is Lefra 20 Tablet used for?
Lefra 20 Tablet is commonly used for This medicine is used in the treatment of pain and swelling, inflammatory arthritis, gout and recovery after injury or surgery. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Lefra 20 Tablet?
Lefra 20 Tablet contains Leflunomide (20mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Lefra 20 Tablet?
Swallow the tablet whole with a glass of water. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Lefra 20 Tablet work?
Leflunomide reduces inflammation and the swelling that comes with injury, surgery or an inflammatory joint disease.
Is Lefra 20 Tablet a prescription medicine?
Yes. Lefra 20 Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Lefra 20 Tablet?
The side effects reported most often with Lefra are Nausea, Stomach upset, Loose motions, Rash, Raised liver enzymes. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Lefra 20 Tablet be taken during pregnancy?
Not recommended in pregnancy — it may harm the developing baby. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Lefra.
Can I drink alcohol while taking Lefra 20 Tablet?
Do not drink alcohol while taking this medicine.
What if I miss a dose of Lefra 20 Tablet?
Take it as soon as you remember.
Is Lefra 20 Tablet habit forming?
No. Lefra 20 Tablet is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Lefra 20 Tablet?
Lefra 10 Tablet has the same active ingredient and strength and is listed from ₹155 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Lefra 20 Tablet cost on PingMeDoc Pharmacy?
Lefra 20 Tablet starts at ₹302 on PingMeDoc Pharmacy. Available in tablet tablet 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Lefra 20 Tablet?
Lefra 20 Tablet is manufactured by TORRENT PHARMACEUTICALS. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Lefra 20 Tablet delivered?
Lefra 20 Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Lefra 20 Tablet, Quick facts

Salt
Leflunomide (20mg)
Form
tablet
Best price
₹302 (₹30.19 per tablet)
Prescription
Required (Rx)
Brand
Torrent Pharmaceuticals Ltd
Manufacturer
TORRENT PHARMACEUTICALS
Therapeutic class
Analgesic and anti-inflammatory
Drug class
Enzyme / disease-modifying anti-rheumatic agent
Habit forming
No
Variants
tablet tablet 10`S
Delivery
Standard across India

References

The information on Lefra 20 Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Lefra 20 Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.