Ace Revelol 25/2.5
IPCA Laboratories Ltd - 10 S
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Prescription requiredIpca Laboratories Ltd`PAIN ANALGESICS
Lefno 20 mg Tablet
Leflunomide (20mg)
₹304MRP ₹3205% offIn stock
Order on WhatsAppDelivered across India in about 3–5 days, Chennai next day. ₹49 delivery, free above ₹999.
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Lefno 20 mg Tablet is used for treatment of Rheumatoid arthritis.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Licensed pharmacyPharmacist-verified orderDelivered across India
Key details
Salt: Leflunomide (20mg)
Available variants: tablet 20 mg 10`S
Best price: ₹304 (₹30.40 per tablet)
MRP: ₹320
Prescription: Required
Manufacturer: IPCA LABORATORIES LTD`
Ordering notes
Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Lefno 20 mg Tablet in Bangladesh
8 brands registered in Bangladesh with the same salt, strength and form.
- ArolefGeneral Pharmaceuticals Ltd.
- DimarOpsonin Pharma Limited
- LefluAlco Pharma Limited
- LemaMystic Pharmaceuticals Ltd.
- LeraGlobe Pharmaceuticals Ltd.
- MotoralAdvanced Chemical Industries PLC.
- NodiaIncepta Pharmaceuticals Ltd.
- SynomidBeximco Pharmaceuticals Ltd.
Brand names differ between countries. Ask a pharmacist or your doctor in Bangladesh before switching. We don't sell or ship these brands. Source: Directorate General of Drug Administration, Bangladesh.
Same salt, lower price
Medicines with the same active ingredient and strength as Lefno 20 mg Tablet.
You are viewing
Lefno 20 mg Tablet
tablet - 20 mg - 10 S
₹304
₹30.40 per tablet
- Lefra 10 Tab 10S
Torrent Pharmaceuticals Ltd · tablet - 20mg - 10 S · Rx
Save 47%₹161
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- Cleft 20MG Tab 10S
SUN PHARMA 2 · tablet - 20 mg - 10 S · Rx
Save 29%₹216
₹21.63 per tablet
- Lefutoid 20MG Tab
LUPIN LAB · tablet - 20 mg - 10 S · Rx
Save 14%₹262
₹26.15 per tablet
Same salt, different brand — what does that mean?
A substitute contains the same active ingredient (salt), in the same strength, as Lefno 20 mg Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.
All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.
Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.
Composition of Lefno 20 mg Tablet
Lefno 20 mg Tablet contains Leflunomide (20mg). It belongs to the Enzyme / disease-modifying anti-rheumatic agent class of medicines.
Uses of Lefno 20 mg Tablet
Treatment of Rheumatoid arthritis
Key benefits
- In Treatment of Rheumatoid arthritis Lefno 20 Tablet reduces pain
- stiffness
- and swelling in your joints and slows down the progression of bone and joint damage. This will help you do normal daily activities more easily and thus improve your quality of life. This medicine should be taken at the same time each day to get maximum benefits. Keep taking it even if you feel well because it is preventing future harm as well as improving your symptoms.
How Lefno 20 mg Tablet works
Lefno 20 Tablet blocks the action of certain chemical messengers that are responsible for inflammation, swelling, and redness associated with certain autoimmune diseases such as rheumatoid arthritis. It suppresses the underlying disease process, rather than simply treating the disease.
How to take Lefno 20 mg Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lefno 20 Tablet may be taken with or without food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
If you miss a dose of Lefno 20 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
If you take too much
An overdose of this medicine can seriously suppress the bone marrow and damage the liver. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Lefno 20 mg Tablet
Most side effects of Lefno are mild and settle as the body adjusts. Reported side effects include:
- Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Lefno 20 mg Tablet
| Pregnancy | Pregnancy UNSAFE |
|---|---|
| Breastfeeding | Breast feeding UNSAFE |
| Alcohol | Alcohol UNSAFE |
| Driving | Driving CONSULT YOUR DOCTOR |
| Kidney | Kidney UNSAFE |
| Liver | Liver UNSAFE |
| Habit forming | No |
Warnings and precautions
Medicines that suppress the immune system need regular blood tests — do not miss them. Report fever, sore throat, mouth ulcers or unusual bruising promptly if you are on an immune-suppressing medicine. Tell your doctor about any infection, and before any vaccination. Methotrexate for arthritis is taken ONCE A WEEK. Taking it daily by mistake is dangerous — check the day on your pack.
Do not take Lefno if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active serious infection, or with severe liver or bone-marrow disease. Several of these medicines must not be used in pregnancy.
Interactions with other medicines
Tell your doctor about all other medicines, especially anti-inflammatory painkillers and antibiotics. Live vaccines are generally avoided while on immune-suppressing treatment.
How to store Lefno 20 mg Tablet
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Expert advice for Lefno 20 mg Tablet
You have been prescribed Lefno 20 Tablet to control the symptoms and slow down the progression of rheumatoid arthritis. It will take 6-8 weeks for Lefno 20 Tablet to work. Hence, keep taking the medicine. Get blood tests done every 4 weeks. This is to make sure that Lefno 20 Tablet is not harming your liver or blood counts. Avoid alcohol when taking Lefno 20 Tablet as it could harm your liver. Do not take it during pregnancy or breastfeeding. Tell your doctor if you become pregnant while taking Lefno 20 Tablet. Lefno 20 Tablet may increase the risk of infection. Avoid being close to people with colds, flu, or other contagious illnesses.
Manufacturer and class
- Manufacturer:
- IPCA LABORATORIES LTD`
- Therapeutic class:
- PAIN ANALGESICS
- Drug class:
- Enzyme / disease-modifying anti-rheumatic agent
- Chemical class:
- Aromatic anilides
Substitutes for Lefno 20 mg Tablet
Medicines with the same active ingredient (Leflunomide (20mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Lefno 20 mg Tablet |
|---|---|---|---|
| Lefra 10 TabletTorrent Pharmaceuticals Ltd | tablet · 10`S | ₹161 | 47% cheaper |
| Cleft 20 mg TabletSUN PHARMA 2 | tablet · 10`S | ₹216 | 29% cheaper |
| Lefutoid 20 mg TabletLUPIN LAB | tablet · 10`S | ₹262 | 14% cheaper |
| Lefra 20 TabletTorrent Pharmaceuticals Ltd | tablet · 10`S | ₹315 | 4% more |
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Lefno 20 mg Tablet FAQs
What is Lefno 20 mg Tablet used for?
Lefno 20 mg Tablet is commonly used for Treatment of Rheumatoid arthritis. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Lefno 20 mg Tablet?
Lefno 20 mg Tablet contains Leflunomide (20mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Lefno 20 mg Tablet?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Lefno 20 mg Tablet work?
Lefno 20 Tablet blocks the action of certain chemical messengers that are responsible for inflammation, swelling, and redness associated with certain autoimmune diseases such as rheumatoid arthritis.
Is Lefno 20 mg Tablet a prescription medicine?
Yes. Lefno 20 mg Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Lefno 20 mg Tablet?
The side effects reported most often with Lefno are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Lefno 20 mg Tablet be taken during pregnancy?
Pregnancy UNSAFE Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Lefno.
Can I drink alcohol while taking Lefno 20 mg Tablet?
Alcohol UNSAFE
What if I miss a dose of Lefno 20 mg Tablet?
If you miss a dose of Lefno 20 Tablet, take it as soon as possible.
Is Lefno 20 mg Tablet habit forming?
No. Lefno 20 mg Tablet is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Lefno 20 mg Tablet?
Lefra 10 Tablet has the same active ingredient and strength and is listed from ₹161 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Lefno 20 mg Tablet cost on PingMeDoc Pharmacy?
Lefno 20 mg Tablet starts at ₹304 (MRP ₹320) on PingMeDoc Pharmacy. Available in tablet 20 mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Lefno 20 mg Tablet?
Lefno 20 mg Tablet is manufactured by IPCA LABORATORIES LTD`. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Lefno 20 mg Tablet delivered?
Lefno 20 mg Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.
Lefno 20 mg Tablet, Quick facts
- Salt
- Leflunomide (20mg)
- Form
- tablet
- Best price
- ₹304 (₹30.40 per tablet)
- MRP
- ₹320
- Prescription
- Required (Rx)
- Schedule
- Schedule H
- Brand
- IPCA LABORATORIES LTD`
- Manufacturer
- IPCA LABORATORIES LTD`
- Therapeutic class
- PAIN ANALGESICS
- Drug class
- Enzyme / disease-modifying anti-rheumatic agent
- Chemical class
- Aromatic anilides
- Action class
- Non-Biologic DMARDs (Disease Modifying Anti-Rheumatoid Drugs)
- Habit forming
- No
- Variants
- tablet 20 mg 10`S
- Delivery
- Standard across India
References
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.
- PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
- CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Lefno 20 mg Tablet.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.