
Ace Revelol 25/2.5
IPCA Laboratories Ltd - 10 S
Prescription required
Leflunomide (20mg)
Lefno 20 mg Tablet is used for treatment of Rheumatoid arthritis.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026
Medicines with the same active ingredient and strength as Lefno 20 mg Tablet.
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Lefno 20 mg Tablet
tablet - 20 mg - 10 S
₹303
₹30.28 per tablet
Torrent Pharmaceuticals Ltd · tablet - 10 S · Rx
₹155
₹15.45 per tablet
LUPIN LAB · tablet - 20 mg - 10 S · Rx
₹275
₹27.53 per tablet
A substitute contains the same active ingredient (salt), in the same strength, as Lefno 20 mg Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.
All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.
Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.
Lefno 20 mg Tablet contains Leflunomide (20mg).
Treatment of Rheumatoid arthritis
Lefno 20 Tablet blocks the action of certain chemical messengers that are responsible for inflammation, swelling, and redness associated with certain autoimmune diseases such as rheumatoid arthritis. It suppresses the underlying disease process, rather than simply treating the disease.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lefno 20 Tablet may be taken with or without food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Lefno 20 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Taking more Lefno than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.
Most side effects of Lefno are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Pregnancy UNSAFE |
|---|---|
| Breastfeeding | Breast feeding UNSAFE |
| Alcohol | Alcohol UNSAFE |
| Driving | Driving CONSULT YOUR DOCTOR |
| Kidney | Kidney UNSAFE |
| Liver | Liver UNSAFE |
| Habit forming | No |
Tell your doctor or pharmacist about every medicine you take, including over-the-counter products, vitamins and herbal or ayurvedic preparations, before starting Lefno. Some combinations can change how Lefno works or raise the chance of side effects.
Store Lefno below 30°C in a cool, dry place away from direct sunlight and moisture. Keep the pack tightly closed and out of the reach of children. Do not use it after the expiry date printed on the pack.
You have been prescribed Lefno 20 Tablet to control the symptoms and slow down the progression of rheumatoid arthritis. It will take 6-8 weeks for Lefno 20 Tablet to work. Hence, keep taking the medicine. Get blood tests done every 4 weeks. This is to make sure that Lefno 20 Tablet is not harming your liver or blood counts. Avoid alcohol when taking Lefno 20 Tablet as it could harm your liver. Do not take it during pregnancy or breastfeeding. Tell your doctor if you become pregnant while taking Lefno 20 Tablet. Lefno 20 Tablet may increase the risk of infection. Avoid being close to people with colds, flu, or other contagious illnesses.
Medicines with the same active ingredient (Leflunomide (20mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Lefno 20 mg Tablet |
|---|---|---|---|
| Lefra 10 TabletTorrent Pharmaceuticals Ltd | tablet · 10`S | ₹155 | 49% cheaper |
| Lefutoid 20 mg TabletLUPIN LAB | tablet · 10`S | ₹275 | 9% cheaper |
| Lefra 20 TabletTorrent Pharmaceuticals Ltd | tablet · 10`S | ₹302 | same price |

IPCA Laboratories Ltd - 10 S
Prescription required
IPCA Laboratories Ltd - 10 S
Prescription required
IPCA Laboratories Ltd - Capsule - 20 mg - 10 S
Prescription required
IPCA Laboratories Ltd - 10 S
Prescription required
IPCA Laboratories Ltd - 10 S
Prescription required

IPCA Laboratories Ltd - 75 G
Prescription required

IPCA Laboratories Ltd - Cream - 30 G

IPCA Laboratories Ltd - Gel - 60 Gms

Aeon Pharma Corporation - Tablet - 14 S
Prescription required

Dr Reddys Laboratories Ltd - Syrup - 100 ml
Prescription required

Axole Pharma - Tablet - 10 S
Prescription required
Beat Pharma - Tablet - 3.125 mg - 10 S
Prescription required

Torrent Pharmaceuticals Ltd - Tablet - 10 Tablet
Prescription required

East West Pharma - Ointment - 15 G
Prescription required
Intas Pharmaceuticals Ltd - 15 S
Prescription required

Walfs Pharma - Capsule - 10 S
Prescription required
Abbott India Limited - Tablet - 21 Tablet
Prescription required

Torrent Pharmaceuticals Ltd - Soap - 125 G

Genfo Bioceuticals Pvt Ltd - Suspension - 170 ml
Prescription required

Novelty Health Shine Pvt Ltd - Tablet - 20 S

Dr Reddys Laboratories Ltd - Gel - 50 G
Prescription required
Dr Reddys Laboratories Ltd - 50 Gms
Prescription required

The Derma Co - Cream - 100 G
Injection - 1 ml
Prescription required
The information on Lefno 20 mg Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.