Lethyrox 12.5

Composition of Lethyrox 12.5

Lethyrox 12.5 contains Levothyroxine sodium 12.5 mcg tablet. It belongs to the Thyroid hormone (synthetic T4) class of medicines.

Uses of Lethyrox 12.5

• Hypothyroidism (underactive thyroid)
• thyroid hormone replacement after thyroidectomy
• goitre/thyroid suppression therapy as advised by doctor

Key benefits

• Replaces deficient thyroid hormone
• Helps normalize TSH and thyroid levels
• Improves symptoms like fatigue and weight gain due to hypothyroidism
• Supports normal metabolism and energy
• Helps maintain normal heart rate and body temperature

How Lethyrox 12.5 works

Levothyroxine is a synthetic form of thyroxine (T4), a natural thyroid hormone. It replaces deficient thyroid hormone and is converted in the body to the active hormone (T3), helping normalize metabolism, energy, heart rate and growth.

How to take Lethyrox 12.5

Oral tablet. Take exactly as prescribed, usually once daily on an empty stomach (preferably morning) 30–60 minutes before food with water. Take at the same time each day; avoid taking along with calcium/iron/antacids—keep a 4-hour gap unless advised otherwise.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause a racing heart, chest pain, tremor, fever and dangerous heart rhythm disturbance. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Lethyrox 12.5

Most side effects of Lethyrox are mild and settle as the body adjusts. Reported side effects include:

• Palpitations
• fast heart rate
• anxiety
• restlessness
• tremor
• headache
• insomnia
• increased sweating
• heat intolerance
• diarrhoea
• weight loss
• menstrual irregularities

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Lethyrox 12.5

Warnings and precautions

Use under medical supervision with regular TSH/T4 monitoring. Overtreatment can cause hyperthyroidism, arrhythmias, angina and bone loss/osteoporosis. Use caution in elderly and in patients with heart disease, hypertension, adrenal insufficiency (should be treated first), and diabetes (may alter glucose control). Not for weight loss/obesity management. Seek urgent care for chest pain, severe palpitations or breathlessness.

Do not take Lethyrox if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an untreated overactive thyroid or untreated adrenal insufficiency.

Interactions with other medicines

Calcium salts,iron salts,antacids containing aluminium/magnesium,sucralfate,cholestyramine/colestipol,sevelamer (reduce absorption); proton pump inhibitors and dietary fibre/soy products may reduce absorption; warfarin (increased anticoagulant effect),antidiabetic medicines (dose adjustment may be needed),amiodarone,carbamazepine,phenytoin,rifampicin,sertraline (may alter thyroid hormone levels),oestrogens/oral contraceptives (may increase requirement)

How to store Lethyrox 12.5

Store below 25°C in a dry place, protected from light and moisture. Keep in original blister/strip and out of reach of children.

Expert advice for Lethyrox 12.5

Keep to the same brand where you can, and take it at the same time every morning. Have your thyroid blood test repeated as your doctor advises after any dose change.

Manufacturer and class

Manufacturer:

INTAS PHARMACEUTICALS`

Therapeutic class:

Thyroid hormone replacement

Drug class:

Thyroid hormone (synthetic T4)