
Acuclav 375
Macleods Pharmaceuticals Pvt Ltd - 10 S
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Levosalbutamol + Ambroxol
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Macbery 12 Syrup is used for this medicine is used in the treatment of asthma, chronic obstructive pulmonary disease, cough, chest congestion and common cold symptoms.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Macbery 12 Syrup contains Levosalbutamol + Ambroxol. It belongs to the Inhaled bronchodilator / corticosteroid and Expectorant / mucolytic / bronchodilator class of medicines.
This medicine combines 2 active ingredients: Levosalbutamol and Ambroxol. Levosalbutamol is breathed straight into the lungs, where it opens the airways and reduces the swelling inside them, so less of the medicine reaches the rest of the body. Ambroxol loosens and thins the mucus in your airways so a cough clears it more easily, and eases the tightness that comes with congestion.
Shake the bottle well before each dose and measure it with the cup, spoon or dropper supplied — a kitchen spoon is not an accurate measure. Take it with or after food. Follow the dose and the duration written on your prescription.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause a racing heart, marked tremor, headache and a fall in blood potassium. It can cause vomiting, severe drowsiness, a racing heart and, with codeine, dangerously slow breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Macbery are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult your doctor before using this in pregnancy. |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | Do not drink alcohol while taking this medicine. |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Use with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function. |
| Liver | Use with caution if you have liver disease — your doctor may adjust the dose or monitor your liver function. |
| Habit forming | No |
Know which of your inhalers is the reliever and which is the preventer. A preventer must be used every day even when you feel well; a reliever is for symptoms. Seek emergency care if your reliever is not working, if you cannot speak a full sentence, or if you are using the reliever far more often than usual. Rinse your mouth with water and spit it out after every steroid inhaler dose to prevent thrush and hoarseness. Ask your doctor or pharmacist to watch your technique — poor technique is the commonest reason an inhaler seems not to work. Use a spacer if one has been advised, particularly for children. See a doctor if a cough lasts more than a week, or comes with fever, breathlessness, chest pain or blood in the sputum. Do not give cough and cold preparations to young children except on a doctor's advice. Do not combine two cough preparations — they frequently contain the same ingredients, and the doses add up. Preparations containing codeine can cause dependence and must be used only for the period your doctor specifies.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for anyone with a known allergy to the propellant used in the inhaler. Codeine-containing preparations are not for children, or for anyone with breathing difficulty.
Beta blockers, including eye drops for glaucoma, can tighten the airways and reduce the effect of your reliever. Sedating ingredients add to the effect of alcohol and sleeping tablets. Decongestants such as phenylephrine and pseudoephedrine can raise blood pressure — tell your doctor if you are hypertensive.
Store below 30°C, away from direct sunlight. Do not freeze. Once opened, use it within the period printed on the pack. Keep out of the reach of children.
Keep a spare reliever and check the counter so you are not caught with an empty one. Follow your written asthma action plan if you have one. Do not stop a preventer because you feel better — that is the medicine working. Drink plenty of water — it thins mucus better than any syrup. Steam inhalation helps congestion and costs nothing. Measure the dose with the cup supplied.

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The information on Macbery 12 Syrup is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.