Metrogyl 200 Tablet

Composition of Metrogyl 200 Tablet

Metrogyl 200 Tablet contains Metronidazole (200mg). It belongs to the Nitroimidazole antimicrobial class of medicines.

Uses of Metrogyl 200 Tablet

• Treatment of susceptible anaerobic bacterial and protozoal infections such as amoebiasis (intestinal/extra-intestinal)
• giardiasis
• trichomoniasis
• bacterial vaginosis
• dental/gingival infections
• and other anaerobic infections as prescribed.

Key benefits

• Treats amoebiasis
• Treats giardiasis
• Treats trichomoniasis
• Effective against anaerobic bacterial infections
• Helps in dental/gingival anaerobic infections

How Metrogyl 200 Tablet works

Metronidazole is an antibiotic/antiprotozoal that enters susceptible organisms and is reduced to reactive metabolites. These metabolites damage DNA and inhibit nucleic acid synthesis, leading to death of anaerobic bacteria and protozoa.

How to take Metrogyl 200 Tablet

Tablet: take exactly as prescribed. Usually taken with or after food to reduce stomach upset. Swallow with water; complete the full course even if you feel better. Avoid alcohol during treatment and for at least 48 hours after the last dose.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Metrogyl 200 Tablet, skip it and continue with your normal schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause vomiting, severe loose motions and nerve symptoms. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Metrogyl 200 Tablet

Most side effects of Metrogyl are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• abdominal pain
• diarrhea
• metallic taste
• dry mouth
• headache
• dizziness
• dark/colored urine
• loss of appetite

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Metrogyl 200 Tablet

Warnings and precautions

Prescription (Schedule H) medicine—use only under medical advice. Avoid alcohol during therapy and for 48 hours after (risk of disulfiram-like reaction). Use with caution in liver disease (dose adjustment may be needed), history of seizures/neurological disorders, and blood dyscrasias; prolonged use may rarely cause peripheral neuropathy. If severe diarrhea, rash, numbness/tingling, or confusion occurs, seek medical advice. May cause dizziness—use caution while driving/operating machinery.

Do not take Metrogyl if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack.

Interactions with other medicines

Alcohol, warfarin/other coumarin anticoagulants (increased bleeding risk), disulfiram (psychosis/confusion risk), lithium (toxicity risk), phenytoin/phenobarbital (reduced metronidazole levels), cimetidine (increased metronidazole levels), busulfan (increased toxicity), 5-fluorouracil (increased toxicity)

How to store Metrogyl 200 Tablet

Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.

Expert advice for Metrogyl 200 Tablet

Take Metrogyl 200 Tablet with a full meal or a glass of milk to reduce the risk of gastrointestinal side effects. Do not drink alcohol during or for 2-3 days after treatment with this medicine. You may develop nausea, vomiting, flushing, and headache (disulfiram-like reaction). Your urine may appear darker or reddish-brown during treatment. This is a known, harmless effect of Metrogyl 200 Tablet and does not indicate kidney damage or bleeding. A temporary metallic or bitter taste in the mouth may occur during therapy. This is a common side effect and usually resolves after completing the treatment. Inform your doctor if you have liver disease. Your dose may need to be adjusted in severe liver disease.

Manufacturer and class

Manufacturer:

JB CHEMICALS

Therapeutic class:

Antibiotic/Antiprotozoal

Drug class:

Nitroimidazole antimicrobial

Chemical class:

Nitroimidazole derivative