
Aldactone 100 Tablet
Rpg Life Sciences Limited - Tablet - 15 Tablet
Prescription required
Naproxen + Domperidone
Naprosyn D 500 is used for this medicine is used in the treatment of pain, inflammation, arthritis, fever, period pain, nausea, vomiting, bloating and slow stomach emptying.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Naprosyn D 500 contains Naproxen + Domperidone. It belongs to the Non-steroidal anti-inflammatory drug and Anti-emetic / prokinetic class of medicines.
This medicine combines 2 active ingredients: Naproxen and Domperidone. Naproxen blocks the chemicals your body makes at a site of injury or inflammation, which reduces pain, swelling and fever. Domperidone settles the stomach and blocks the signals that trigger nausea and vomiting, and helps the stomach empty at a normal rate.
Use this medicine as your doctor has directed. Follow the dose and the duration written on your prescription.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause stomach bleeding, kidney failure, drowsiness and fits. It can cause drowsiness, disorientation and abnormal muscle movements. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Naprosyn D are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Not recommended in pregnancy — it may harm the developing baby. Tell your doctor at once if you are or might be pregnant. |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | Do not drink alcohol while taking this medicine. |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Consult your doctor if you have kidney disease. |
| Liver | Consult your doctor if you have liver disease. |
| Habit forming | No |
Take it with or just after food, and for the shortest time that works. Stop and seek urgent care for black or tarry stools, vomiting blood, or severe stomach pain — this group can cause bleeding from the stomach. Long or high-dose use raises the risk of heart attack, stroke and kidney injury, particularly in older people and those already at risk. Avoid if you are dehydrated or have an illness with vomiting or loose motions — the kidneys are vulnerable then. Must be avoided in the last three months of pregnancy. Use it for the shortest period that works. These medicines are not intended for long-term daily use. Report any unusual muscle stiffness, tremor, restlessness or uncontrolled movements of the face or limbs at once — stop and contact your doctor. Tell your doctor if you have a heart rhythm problem; some of this group affect the heart's electrical timing. Persistent vomiting needs a diagnosis. Do not keep suppressing it without seeing a doctor, especially with abdominal pain, fever or blood.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy. Not for people with bleeding, blockage or perforation of the gut, or with certain heart rhythm disorders.
Combining with a blood thinner or aspirin sharply raises the bleeding risk. Reduces the effect of blood pressure medicines and water tablets, and together with them can harm the kidneys. Never take two anti-inflammatory painkillers at the same time. Antifungals, some antibiotics and heart-rhythm medicines increase the risk of rhythm problems when combined. Adds to the drowsiness of alcohol and sedatives.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Use the lowest dose for the shortest period. If you need a painkiller regularly, see your doctor rather than continuing on your own. Paracetamol is the safer choice for simple fever and headache. Take it shortly before meals for bloating and early fullness. Sip fluids frequently in small amounts, and use oral rehydration salts if you have been vomiting.

Rpg Life Sciences Limited - Tablet - 15 Tablet
Prescription required
Rpg Life Sciences Limited - Tablet - 15 Tablet
Prescription required

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Prescription required

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Prescription required
The information on Naprosyn D 500 is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.