Neosporin Skin Ointment

Composition of Neosporin Skin Ointment

Neosporin Skin Ointment contains Bacitracin zinc 250 IU/g + Neomycin sulfate 3.5 mg/g + Polymyxin B sulfate 5000 IU/g. It belongs to the Polypeptide antibiotic + Aminoglycoside antibiotic (combination) class of medicines.

Uses of Neosporin Skin Ointment

• Prevention and treatment of minor skin infections in small cuts
• wounds
• abrasions
• burns; helps prevent bacterial infection in minor skin injuries

Key benefits

• Helps prevent infection in minor cuts and abrasions
• Treats minor superficial bacterial skin infections
• Broad antibacterial coverage
• Supports faster healing by controlling bacteria

How Neosporin Skin Ointment works

This is a topical triple-antibiotic combination. Bacitracin inhibits bacterial cell wall synthesis, while neomycin (an aminoglycoside) and polymyxin B disrupt bacterial protein synthesis and cell membrane integrity, providing broad antibacterial coverage against common skin pathogens.

How to take Neosporin Skin Ointment

For external use only. Clean and dry the affected area, then apply a thin layer 1–3 times daily or as directed by a doctor; may be covered with a sterile bandage. Avoid contact with eyes, mouth and inside the nose; wash hands before and after use.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Apply it as soon as you remember. If it is nearly time for the next application, skip the missed one — applying extra does not make up for it.

If you take too much

An overdose of this medicine can cause vomiting, severe loose motions and nerve symptoms. It is unlikely from skin use. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Neosporin Skin Ointment

Most side effects of Neosporin Skin are mild and settle as the body adjusts. Reported side effects include:

• Mild burning/stinging
• itching
• redness
• rash
• dryness
• contact dermatitis
• allergic reaction

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Neosporin Skin Ointment

Warnings and precautions

Do not use on large areas, deep puncture wounds, serious burns, or for prolonged periods unless advised by a doctor. Stop use and seek medical advice if irritation, rash, swelling or no improvement in 3–5 days occurs. Avoid use if allergic to bacitracin, neomycin, polymyxin B or other aminoglycosides. Use caution in patients with significant skin barrier damage as neomycin can rarely be absorbed and cause toxicity; avoid in ear if eardrum is perforated.

Do not take Neosporin Skin if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for use in or around the eyes.

Interactions with other medicines

Other topical antibiotics/antiseptics on same area (increased irritation/sensitization), concurrent aminoglycosides (e.g., gentamicin, amikacin) if significant systemic absorption occurs, neuromuscular blockers (theoretical with systemic absorption)

How to store Neosporin Skin Ointment

Store below 25°C in a cool, dry place. Keep tube tightly closed and protect from excessive heat and moisture.

Expert advice for Neosporin Skin Ointment

Space the doses evenly and complete the course. Take tetracyclines with a full glass of water and stay upright for half an hour afterwards. Never use a leftover antibiotic, or someone else's, for a new illness. Wash your hands before and after applying, and cover the area if advised. Do not share towels or bedding while an infection is active.

Manufacturer and class

Manufacturer:

GLAXO SMITHKLINE PHARMA

Therapeutic class:

Topical antibiotic

Drug class:

Polypeptide antibiotic + Aminoglycoside antibiotic (combination)