
Acuclav 375
Macleods Pharmaceuticals Pvt Ltd - 10 S
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Prescription required
Levosulpiride (75mg) + Pantoprazole (40mg)
Currently out of stock
Same composition, in stock now. Check with your doctor or pharmacist before you switch.
Nupenta Ls is used for treatment of Gastroesophageal reflux disease (Acid reflux).
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Nupenta Ls contains Levosulpiride (75mg) + Pantoprazole (40mg). It belongs to the Anti-emetic / prokinetic and Proton pump inhibitor class of medicines.
Treatment of Gastroesophageal reflux disease (Acid reflux)
Levosulpiride is a prokinetic that works by increasing the release of acetylcholine (a chemical messenger). This increases the movement of the stomach and intestines and prevents reflux (acid going up to the food pipe). Pantoprazole is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach, which helps in the relief of acid-related indigestion and ulcers.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nupenta LS Capsule SR may be taken with or without food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of Nupenta LS Capsule SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
An overdose of this medicine can cause drowsiness, disorientation and abnormal muscle movements. It may cause confusion, blurred vision, sweating and a fast heartbeat. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Nupenta Ls are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Pregnancy CONSULT YOUR DOCTOR |
|---|---|
| Breastfeeding | Breast feeding CONSULT YOUR DOCTOR |
| Alcohol | Alcohol UNSAFE |
| Driving | Driving UNSAFE |
| Kidney | Kidney CAUTION |
| Liver | Liver CAUTION |
| Habit forming | No |
Use it for the shortest period that works. These medicines are not intended for long-term daily use. Report any unusual muscle stiffness, tremor, restlessness or uncontrolled movements of the face or limbs at once — stop and contact your doctor. Tell your doctor if you have a heart rhythm problem; some of this group affect the heart's electrical timing. Persistent vomiting needs a diagnosis. Do not keep suppressing it without seeing a doctor, especially with abdominal pain, fever or blood. Take it on an empty stomach, about half an hour to an hour before your first meal — this is when the acid pumps are most active and the medicine works best. Long-term use has been linked to low magnesium and low vitamin B12, and to a higher risk of bone fracture. Review the need with your doctor rather than continuing indefinitely. Tell your doctor if acidity comes with difficulty swallowing, vomiting, weight loss, or black stools — these need investigation, not a longer course. Do not stop a long course abruptly; acid can rebound. Your doctor will taper it.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with bleeding, blockage or perforation of the gut, or with certain heart rhythm disorders.
Antifungals, some antibiotics and heart-rhythm medicines increase the risk of rhythm problems when combined. Adds to the drowsiness of alcohol and sedatives. Reduces the absorption of some antifungals, iron and certain HIV medicines. Tell your doctor if you take clopidogrel, methotrexate or a blood thinner.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Nupenta LS Capsule SR can be taken with or without food. Take it preferably 30 minutes before food. Inform your doctor if you get watery diarrhea or stomach pain that does not go away. Do not consume alcohol while taking Nupenta LS Capsule SR, as it can increase the risk of stomach damage. Long-term use of Nupenta LS Capsule SR may cause weak or broken bones. Take an adequate intake of dietary calcium and vitamin D or their supplements. Do not take Nupenta LS Capsule SR for longer than prescribed. Nupenta LS Capsule SR is prescribed to give relief from acidity and its associated symptoms.
Medicines with the same active ingredient (Levosulpiride (75mg) + Pantoprazole (40mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Nupenta Ls |
|---|---|---|---|
| Pantomay-L Capsule | 10 | ₹171 | 21% cheaper |
| Pantocaf-Lsr Capsule | 1X10 | ₹251 | 15% more |
| Pan L CapsuleALKEM LAB | capsule · 10`S | ₹310 | 42% more |

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The information on Nupenta Ls is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.