Skip to main content
PingMeDoc
Prescription requiredTorrent Pharmaceuticals LtdAntidepressant and Neuropathic pain agent

Pregalin SR 150

Nortriptyline + Pregabalin

Available at our pharmacy counter

This medicine is dispensed in person against a valid prescription and is not sold online. Ask our pharmacist about availability, or speak to a registered doctor.

In-store reference price ₹325

Pregalin SR 150 is used for this medicine is used in the treatment of depression, anxiety, obsessive compulsive disorder, nerve pain, migraine prevention, diabetic neuropathy, pain after shingles, fibromyalgia and epilepsy.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Nortriptyline + Pregabalin
Available variants: NA 10`S
Best price: ₹325
MRP: ₹342
Prescription: Required
Manufacturer: TORRENT PHARMACEUTICALS

Ordering notes

This medicine is dispensed in person at a licensed pharmacy counter and is not delivered.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Pregalin SR 150

Pregalin SR 150 contains Nortriptyline + Pregabalin. It belongs to the Antidepressant and Gabapentinoid class of medicines.

Uses of Pregalin SR 150

  • Depression
  • Anxiety
  • Obsessive compulsive disorder
  • Nerve pain
  • Migraine prevention
  • Diabetic neuropathy
  • Pain after shingles
  • Fibromyalgia
  • Epilepsy

Benefits of Pregalin SR 150

In Depression
Pregalin SR restores the balance of the brain's chemical messengers, gradually lifting mood, energy, sleep and appetite. The benefit builds over several weeks, which is why it is important to keep taking it.
In Anxiety
Pregalin SR calms persistent worry and the physical tension that goes with it, so that everyday situations feel manageable again.
In Obsessive compulsive disorder
Pregalin SR reduces the intrusive thoughts and the urge to repeat rituals, usually alongside talking therapy.
In Nerve pain
Pregalin SR dampens the pain signals from damaged nerves, easing burning, shooting or tingling pain that ordinary painkillers do not touch.
In Migraine prevention
Pregalin SR, taken every day, reduces how often migraines come and how severe they are. It does not treat an attack once it has started.
In Diabetic neuropathy
Pregalin SR eases the burning, tingling and numbness in the feet and hands caused by diabetic nerve damage, improving sleep and comfort.
In Pain after shingles
Pregalin SR relieves the persistent, sensitive pain that can linger in the skin after a shingles rash has healed.
In Fibromyalgia
Pregalin SR reduces the widespread pain and improves the sleep disturbance of fibromyalgia.
In Epilepsy
Pregalin SR steadies the electrical activity in the brain, reducing how often seizures occur when taken alongside other anti-epileptic medicines.

How Pregalin SR 150 works

This medicine combines 2 active ingredients: Nortriptyline and Pregabalin. Nortriptyline restores the balance of the chemical messengers in the brain that regulate mood, sleep and the way pain is felt. Pregabalin calms the over-active nerve signals that cause burning, shooting and tingling pain.

How to take Pregalin SR 150

Use this medicine as your doctor has directed. Follow the dose and the duration written on your prescription.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause fits, dangerous heart rhythm disturbance and coma, and is particularly dangerous with the older tricyclic medicines. It can cause deep drowsiness, confusion, unsteadiness and slowed breathing, especially with an opioid or alcohol. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Pregalin SR 150

Most side effects of Pregalin SR are mild and settle as the body gets used to the medicine. The ones reported most often are:

  • Nausea
  • Dry mouth
  • Drowsiness or difficulty sleeping
  • Headache
  • Weight change
  • Reduced sexual desire
  • Constipation
  • Drowsiness
  • Dizziness
  • Swelling of the ankles and feet
  • Weight gain
  • Blurred vision
  • Unsteadiness

Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Pregalin SR 150

AlcoholUNSAFE
Do not drink alcohol while taking this medicine.
PregnancyUNSAFE
Not recommended in pregnancy. It may harm the developing baby, so tell your doctor at once if you are or might be pregnant.
Breast feedingCONSULT YOUR DOCTOR
Consult your doctor before using this while breastfeeding.
DrivingUNSAFE
Do not drive or operate machinery while taking this medicine.
KidneyCONSULT YOUR DOCTOR
Consult your doctor if you have kidney disease.
LiverCONSULT YOUR DOCTOR
Consult your doctor if you have liver disease.
Habit formingYES
This medicine can cause dependence with prolonged use. Take it only under medical supervision and do not stop it abruptly.

Warnings and precautions

These medicines take two to four weeks to begin working, and longer for the full effect. Stopping at two weeks because nothing has changed is the commonest mistake. Never stop suddenly. Abrupt withdrawal causes dizziness, electric-shock sensations, irritability and flu-like symptoms — your doctor will reduce the dose gradually. Tell your doctor or go to hospital immediately if thoughts of harming yourself appear or worsen, particularly in the first weeks or after a dose change, and especially in anyone under twenty-five. Seek urgent care for agitation with fever, shivering, a racing heart, muscle twitching or confusion, particularly if more than one medicine affecting serotonin is being taken. Side effects are usually worst in the first fortnight and then settle. This medicine causes drowsiness and unsteadiness, particularly when you start it or the dose goes up. Do not drive or operate machinery until you know how it affects you. Never stop it suddenly. Stopping abruptly can cause anxiety, sleeplessness, sweating and, in people taking it for epilepsy, fits. Your doctor will taper it. Tell your doctor about any change in mood or any thoughts of harming yourself. The dose is usually built up slowly from a low starting point — follow the schedule your doctor gave you rather than jumping to the full dose. Pregabalin comes under Schedule H1 from 16 November 2026 and will then need a prescription and a pharmacy register entry.

Do not take Pregalin SR if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be combined with a monoamine oxidase inhibitor, or started within the gap your doctor specifies after one.

Interactions with other medicines

Tramadol, triptans for migraine, linezolid, St John's wort and other antidepressants can together raise serotonin dangerously. Anti-inflammatory painkillers and blood thinners increase the bleeding risk when combined with this group. Opioid painkillers, alcohol, sleeping tablets and antihistamines all add to the drowsiness, and the combination with opioids can dangerously slow breathing. Antacids reduce the absorption of gabapentin — separate them by a couple of hours.

How to store Pregalin SR 150

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Quick tips for Pregalin SR 150

  • Give it a fair trial of several weeks, and keep your review appointments.
  • Take it at the same time each day.
  • At night if it makes you drowsy, in the morning if it disturbs sleep.
  • Talking therapy alongside medicine works better than either alone for most people.
  • Take the larger part of the dose at night if drowsiness is a problem.
  • Rise slowly from sitting or lying, especially in the first weeks.
  • Keep your review appointment so the dose can be adjusted to the lowest that controls your pain.

Manufacturer and class

Manufacturer:
TORRENT PHARMACEUTICALS
Therapeutic class:
Antidepressant and Neuropathic pain agent
Drug class:
Antidepressant and Gabapentinoid

More from Torrent Pharmaceuticals Ltd

View categories
Acnemoist Bar
5% off

Acnemoist Bar

Torrent Pharmaceuticals Ltd - 100 G

₹283.58₹298.50

Save ₹14.92

Acnemoist Bk Cream
5% off

Acnemoist Bk Cream

Torrent Pharmaceuticals Ltd - Cream - 60 G

₹560.50₹590

Save ₹29.50

5% offRx

Acnetor Ad

Torrent Pharmaceuticals Ltd - 15 G

₹402.25₹423.42

Save ₹21.17

Prescription required

5% offRx

Afogatran 110MG Cap

Torrent Pharmaceuticals Ltd - Capsule - 110 mg - 10 S

₹322.77₹339.75

Save ₹16.98

Prescription required

Afogatran 150
5% offRx

Afogatran 150

Torrent Pharmaceuticals Ltd - 10

₹362.96₹382.06

Save ₹19.10

Prescription required

5% offRx

Afoglip Tab

Torrent Pharmaceuticals Ltd - Tablet - 30 S

₹339.65₹357.52

Save ₹17.87

Prescription required

Aha Glow Advan Face Wash.
5% off

Aha Glow Advan Face Wash.

Torrent Pharmaceuticals Ltd - 100 G

₹536.75₹565

Save ₹28.25

Aha Glow S Spray
5% off

Aha Glow S Spray

Torrent Pharmaceuticals Ltd - Spray - 60 ml

₹641.25₹675

Save ₹33.75

More in Antidepressants

View categories
Aceco Ps Tab
5% offRx

Aceco Ps Tab

Lewin Healthcare - Tablet - 100mg + 325mg - 10 S

₹109.25₹115

Save ₹5.75

Prescription required

5% offRx

Alzolam 0.5

Sun Pharma - 10 S

₹46.32₹48.75

Save ₹2.43

Prescription required

Available in store

In-store
Anaflam-Th4 Tab
5% offRx

Anaflam-Th4 Tab

Albert David Ltd - Tablet - 100mg + 325mg + 4mg - 10 S

₹208.35₹219.31

Save ₹10.96

Prescription required

Briv Syrup
5% offRx

Briv Syrup

Dr Reddys Laboratories Ltd - Syrup - 10mg - 100 ml

₹423.70₹446

Save ₹22.30

Prescription required

Cismatrix Tab
5% offRx

Cismatrix Tab

Kalpa Health Care Pvt Ltd - Tablet - 10 S

₹190₹200

Save ₹10

Prescription required

5% offRx

Clonil 75 SR

Intas Pharmaceuticals Ltd - 15 S

₹252.28₹265.55

Save ₹13.27

Prescription required

Divalex Od - 250MG Tab
5% offRx

Divalex Od - 250MG Tab

Crescent Forumulations Pvt Ltd - Tablet - 250 mg - 10 S

₹99.78₹105.03

Save ₹5.25

Prescription required

Dolokind 10S
5% offRx

Dolokind 10S

Mankind (Pharma) - 10 S

₹41.73₹43.92

Save ₹2.19

Prescription required

Popular on PingMeDoc Pharmacy

View categories
Dermatouch Bye Bye Acne Scars And Marks Cream
40% offOut of stock

Dermatouch Bye Bye Acne Scars And Marks Cream

Cloud Wellness Pvt. Ltd. - Cream - 30 G

₹294₹490

Save ₹196

10% offRx

Suhagra 100 Tablet

Common Products - Tablet - 4 Tablet

₹196.02₹217.80

Save ₹21.78

Prescription required

Xyzal Nasal Spray
10% offRx

Xyzal Nasal Spray

Dr Reddys Laboratories Ltd - Spray - 6 G

₹529.46₹588.28

Save ₹58.82

Prescription required

10% offRx

Zedott Baby Sachet

Torrent Pharmaceuticals Ltd - Powder - 1 G

₹19.49₹21.65

Save ₹2.16

Prescription required

Zeepam Injection
Rx

Zeepam Injection

Tamman Titoe Pharma Pvt Ltd - Injection - 2 ml

₹12.38

Prescription required

Available in store

In-store
Zerolac Powder

Zerolac Powder

Raptokos & Brett - Powder - 400 G

₹308
Xyzal Syrup
10% off

Xyzal Syrup

Dr Reddys Laboratories Ltd - Syrup - 60 ml

₹167.49₹186.09

Save ₹18.60

Zincofer Tablet
10% off

Zincofer Tablet

Apex Laboratories Ltd - Tablet - 10 Tablet

₹42.95₹47.72

Save ₹4.77

Pregalin SR 150 FAQs

What is Pregalin SR 150 used for?
Pregalin SR 150 is commonly used for depression, anxiety, obsessive compulsive disorder, nerve pain, migraine prevention, diabetic neuropathy, pain after shingles, fibromyalgia and epilepsy. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Pregalin SR 150?
Depression: Pregalin SR restores the balance of the brain's chemical messengers, gradually lifting mood, energy, sleep and appetite. The benefit builds over several weeks, which is why it is important to keep taking it. It is also used for anxiety, obsessive compulsive disorder, nerve pain.
What is the salt in Pregalin SR 150?
Pregalin SR 150 contains Nortriptyline + Pregabalin. If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Pregalin SR 150?
Use this medicine as your doctor has directed. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Pregalin SR 150 work?
This medicine combines 2 active ingredients: Nortriptyline and Pregabalin.
Is Pregalin SR 150 a prescription medicine?
Yes. Pregalin SR 150 is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Pregalin SR 150?
The side effects reported most often with Pregalin SR are Nausea, Dry mouth, Drowsiness or difficulty sleeping, Headache, Weight change. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Pregalin SR 150 be taken during pregnancy?
Pregalin SR 150 is not recommended in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Pregalin SR.
Can I drink alcohol while taking Pregalin SR 150?
No. Do not drink alcohol while taking Pregalin SR 150.
What if I miss a dose of Pregalin SR 150?
Take it as soon as you remember.
Is Pregalin SR 150 habit forming?
Yes. Pregalin SR 150 can cause dependence with prolonged use. Take Pregalin SR only as directed and for the duration your doctor advises.
How much does Pregalin SR 150 cost on PingMeDoc Pharmacy?
Pregalin SR 150 starts at ₹325 (MRP ₹342) on PingMeDoc Pharmacy. Available in NA 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Pregalin SR 150?
Pregalin SR 150 is manufactured by TORRENT PHARMACEUTICALS. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Pregalin SR 150 delivered?
Pregalin SR 150 is a regulated medicine and is not delivered. It is dispensed in person at a licensed pharmacy counter against a valid prescription. Ask our pharmacist on WhatsApp about availability.

Pregalin SR 150, Quick facts

Salt
Nortriptyline + Pregabalin
Best price
₹325
MRP
₹342
Prescription
Required (Rx)
Brand
Torrent Pharmaceuticals Ltd
Manufacturer
TORRENT PHARMACEUTICALS
Therapeutic class
Antidepressant and Neuropathic pain agent
Drug class
Antidepressant and Gabapentinoid
Habit forming
Yes
Variants
NA 10`S
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Pregalin SR 150.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.