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OTC · No prescriptionEast India Pharmaceutical Works LtdAnalgesic, Antipyretic

Pyrigesic 650 Tablet

Paracetamol (Acetaminophen) 650 mg tablet

₹31MRP ₹32In stock

Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.

Pyrigesic 650 Tablet is used for fever, mild to moderate pain such as headache, body ache, toothache, sore throat, backache, muscle pain, pain associated with cold/flu.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Paracetamol (Acetaminophen) 650 mg tablet
Available variants: tablet 650mg 15`S
Best price: ₹31 (₹2.04 per tablet)
MRP: ₹32
Prescription: Not required
Manufacturer: EAST INDIA PHARMACEUTICAL WORK

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Same salt, lower price

Medicines with the same active ingredient and strength as Pyrigesic 650 Tablet.

You are viewing

Pyrigesic 650 Tablet

tablet - 650mg - 15 S

₹31

₹2.04 per tablet

  • Kaldomol 650MG Tab

    ALTOR LIFE SCIENCES · tablet - 650 mg - 15 S

    ₹29

    ₹1.94 per tablet

  • Medi 650 Tab

    XEMEX PHARMA · tablet - 650mg - 10 S

    ₹20

    ₹2.00 per tablet

Compare all substitutes
Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Pyrigesic 650 Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Composition of Pyrigesic 650 Tablet

Pyrigesic 650 Tablet contains Paracetamol (Acetaminophen) 650 mg tablet. It belongs to the Non-opioid analgesic (para-aminophenol derivative) class of medicines.

Uses of Pyrigesic 650 Tablet

  • Fever
  • mild to moderate pain such as headache
  • body ache
  • toothache
  • sore throat
  • backache
  • muscle pain
  • pain associated with cold/flu

Key benefits

  • Reduces fever
  • Relieves headache and body pain
  • Helps in cold/flu fever
  • Gentle on stomach compared to many NSAIDs

How Pyrigesic 650 Tablet works

Paracetamol reduces fever and relieves pain by inhibiting prostaglandin synthesis in the central nervous system. It acts on the heat-regulating center in the brain to bring down raised body temperature.

How to take Pyrigesic 650 Tablet

Tablet for oral use. Take as advised by a doctor; commonly 1 tablet every 6–8 hours as needed. Can be taken with or without food (take after food if stomach upset). Do not exceed the recommended daily dose; avoid taking multiple products containing paracetamol together.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause severe and sometimes fatal liver damage, often with no symptoms at all for the first day. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Pyrigesic 650 Tablet

Most side effects of Pyrigesic are mild and settle as the body adjusts. Reported side effects include:

  • Nausea
  • vomiting
  • stomach pain
  • indigestion
  • rash
  • allergic reactions
  • increased liver enzymes (with high doses)

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Pyrigesic 650 Tablet

PregnancyGenerally safe when used as directed; consult doctor
BreastfeedingGenerally considered safe while breastfeeding.
AlcoholAvoid (increases risk of liver damage)
DrivingNot expected to affect your ability to drive.
KidneyUse with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function.
LiverConsult your doctor if you have liver disease.
Habit formingNo

Warnings and precautions

Do not exceed dose—overdose can cause serious liver damage. Use with caution in liver disease, chronic alcohol use, malnutrition, severe kidney disease, or if taking other paracetamol-containing medicines. Seek medical help immediately in case of overdose even if feeling well. Stop and consult a doctor if rash/allergy occurs or fever/pain persists.

Do not take Pyrigesic if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe liver disease, except under medical supervision.

Interactions with other medicines

Alcohol, warfarin/other coumarin anticoagulants (with prolonged use), isoniazid, rifampicin, carbamazepine, phenytoin, phenobarbital/primidone, other hepatotoxic drugs, cholestyramine (reduces absorption), metoclopramide/domperidone (may increase absorption)

How to store Pyrigesic 650 Tablet

Store below 25°C in a dry place, protected from moisture and direct light. Keep out of reach of children.

Expert advice for Pyrigesic 650 Tablet

Take the lowest dose that works, and leave the stated gap between doses. Seek help immediately after a suspected overdose, even if you feel completely well — treatment works best when it is early.

Manufacturer and class

Manufacturer:
EAST INDIA PHARMACEUTICAL WORK
Therapeutic class:
Analgesic, Antipyretic
Drug class:
Non-opioid analgesic (para-aminophenol derivative)

Substitutes for Pyrigesic 650 Tablet

Medicines with the same active ingredient (Paracetamol (Acetaminophen) 650 mg tablet). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Pyrigesic 650 Tablet
Medi 650 TabletXEMEX PHARMAtablet · 10`S₹2035% cheaper
Kaldomol 650 mg TabletALTOR LIFE SCIENCEStablet · 15`S₹295% cheaper
Lg Para TLIFE GAIN PHARMA10`S₹83173% more
See all substitutes and alternatives

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Pyrigesic 650 Tablet FAQs

What is Pyrigesic 650 Tablet used for?
Pyrigesic 650 Tablet is commonly used for Fever, mild to moderate pain such as headache, body ache, toothache, sore throat, backache, muscle pain, pain associated with cold/flu. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Pyrigesic 650 Tablet?
Pyrigesic 650 Tablet contains Paracetamol (Acetaminophen) 650 mg tablet. If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Pyrigesic 650 Tablet?
Tablet for oral use. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Pyrigesic 650 Tablet work?
Paracetamol reduces fever and relieves pain by inhibiting prostaglandin synthesis in the central nervous system.
Is Pyrigesic 650 Tablet a prescription medicine?
No. Pyrigesic 650 Tablet is available over the counter (OTC), no prescription is required. However, it is always safer to consult a doctor or pharmacist before use.
What are the common side effects of Pyrigesic 650 Tablet?
The side effects reported most often with Pyrigesic are Nausea, vomiting, stomach pain, indigestion, rash. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Pyrigesic 650 Tablet be taken during pregnancy?
Generally safe when used as directed; consult doctor Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Pyrigesic.
Can I drink alcohol while taking Pyrigesic 650 Tablet?
Avoid (increases risk of liver damage)
What if I miss a dose of Pyrigesic 650 Tablet?
Take it as soon as you remember.
Is Pyrigesic 650 Tablet habit forming?
No. Pyrigesic 650 Tablet is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Pyrigesic 650 Tablet?
Medi 650 Tablet has the same active ingredient and strength and is listed from ₹20 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Pyrigesic 650 Tablet cost on PingMeDoc Pharmacy?
Pyrigesic 650 Tablet starts at ₹31 (MRP ₹32) on PingMeDoc Pharmacy. Available in tablet 650mg 15`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Pyrigesic 650 Tablet?
Pyrigesic 650 Tablet is manufactured by EAST INDIA PHARMACEUTICAL WORK. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Pyrigesic 650 Tablet delivered?
Pyrigesic 650 Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Pyrigesic 650 Tablet, Quick facts

Salt
Paracetamol (Acetaminophen) 650 mg tablet
Form
tablet
Best price
₹31 (₹2.04 per tablet)
MRP
₹32
Prescription
Not required (OTC)
Brand
East India Pharmaceutical Works Ltd
Manufacturer
EAST INDIA PHARMACEUTICAL WORK
Therapeutic class
Analgesic, Antipyretic
Drug class
Non-opioid analgesic (para-aminophenol derivative)
Habit forming
No
Variants
tablet 650mg 15`S
Delivery
Standard across India

References

The information on Pyrigesic 650 Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Manufacturer labeling
  2. Indian Pharmacopoeia/standard drug monographs, established medical literature (paracetamol), clinical prescribing information
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Pyrigesic 650 Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.