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Prescription requiredLupin LabAnti-hypertensive

Ramistar M XL 25

Metoprolol + Ramipril

₹219MRP ₹2305% offIn stock
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Delivered across India, usually 8–11 days after the order is confirmed. ₹49 delivery, free above ₹999.

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Ramistar M XL 25 is used for this medicine is used in the treatment of high blood pressure, angina, heart failure, irregular heartbeat and diabetic kidney disease.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Metoprolol + Ramipril
Available variants: NA 10`S
Best price: ₹219
MRP: ₹230
Prescription: Required
Manufacturer: LUPIN LAB

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Ramistar M XL 25

Ramistar M XL 25 contains Metoprolol + Ramipril. It belongs to the Beta blocker and Angiotensin receptor blocker / ACE inhibitor class of medicines.

Uses of Ramistar M XL 25

  • High blood pressure
  • Angina
  • Heart failure
  • Irregular heartbeat
  • Diabetic kidney disease

Benefits of Ramistar M XL 25

In High blood pressure
Ramistar M XL slows the heart a little and lets it beat with less force, bringing blood pressure down and reducing the long-term risk of stroke and heart attack.
In Angina
Ramistar M XL reduces how hard the heart has to work, so it needs less oxygen and you get fewer episodes of chest pain on exertion.
In Heart failure
Ramistar M XL protects a weakened heart from the stress hormones that would otherwise strain it further, improving how well it pumps over time and lowering the risk of hospital admission.
In Irregular heartbeat
Ramistar M XL steadies the heart's rhythm and keeps the rate from racing, which eases palpitations and the dizziness or breathlessness that come with them.
In Diabetic kidney disease
Ramistar M XL reduces the pressure inside the kidneys' filters and cuts the protein leaking into the urine, slowing the kidney damage that diabetes causes.

How Ramistar M XL 25 works

This medicine combines 2 active ingredients: Metoprolol and Ramipril. Metoprolol slows the heart and reduces the force of each beat by blocking the effect of adrenaline, so the heart works less hard and uses less oxygen. Ramipril relaxes and widens your blood vessels by blocking a hormone that narrows them, so your heart does not have to push as hard and your blood pressure falls.

How to take Ramistar M XL 25

Use this medicine as your doctor has directed. Follow the dose and the duration written on your prescription.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause a dangerously slow heartbeat, a severe fall in blood pressure, wheezing and fits. It can cause a severe fall in blood pressure, with dizziness, fainting and a fast or slow pulse. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Ramistar M XL 25

Most side effects of Ramistar M XL are mild and settle as the body gets used to the medicine. The ones reported most often are:

  • Tiredness
  • Cold hands and feet
  • Slow pulse
  • Dizziness
  • Disturbed sleep
  • Breathlessness
  • Dizziness on standing up
  • Headache
  • Raised potassium
  • Dry cough

Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Ramistar M XL 25

AlcoholCAUTION
Alcohol may worsen the side effects of this medicine. Limit it.
PregnancyUNSAFE
Not recommended in pregnancy. It may harm the developing baby, so tell your doctor at once if you are or might be pregnant.
Breast feedingCONSULT YOUR DOCTOR
Consult your doctor before using this while breastfeeding.
DrivingCAUTION
May cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyCONSULT YOUR DOCTOR
Consult your doctor if you have kidney disease.
LiverCAUTION
Use with caution if you have liver disease. Your doctor may adjust the dose or monitor your liver function.

Warnings and precautions

Never stop this medicine suddenly. Stopping abruptly can cause a sharp rise in blood pressure, worsening chest pain or a heart attack — your doctor will reduce it gradually. Tell your doctor if you have asthma or long-standing lung disease; this group can tighten the airways. If you have diabetes, be aware that this medicine can mask the early warning signs of low blood sugar, apart from sweating. Report a resting pulse that is persistently very slow, or fainting. Stand up slowly for the first few days — dizziness on rising is common when you start or your dose goes up. Stop and seek urgent care if your lips, tongue, face or throat swell, or you have difficulty breathing. A persistent dry, tickly cough can be caused by the ACE inhibitor group; tell your doctor rather than stopping on your own, as an alternative exists. Your doctor will check your kidney function and potassium after starting and after any dose change. Do not use salt substitutes containing potassium without asking your doctor.

Do not take Ramistar M XL if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with a very slow heart rate, certain heart block disorders, or uncontrolled heart failure. Generally avoided in severe asthma. Must not be used in pregnancy — it can seriously harm the developing baby. Not for people with narrowing of both kidney arteries, or a history of swelling of the face and throat caused by this group of medicines.

Interactions with other medicines

Combining with verapamil or diltiazem can slow the heart dangerously. Tell your doctor about diabetes medicines and about any asthma inhaler. Anti-inflammatory painkillers reduce the effect and can harm the kidneys when combined. Potassium supplements, potassium-sparing water tablets and salt substitutes can push potassium too high. Lithium levels rise when taken with these medicines.

How to store Ramistar M XL 25

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Quick tips for Ramistar M XL 25

  • Take it at the same time each day and do not miss doses.
  • Learn to check your own pulse, and report a persistently slow one.
  • Blood pressure medicines work only while you take them.
  • Do not stop because you feel well.
  • Tell your doctor at once if you become pregnant or are planning a pregnancy.
  • Keep a home blood-pressure record if your doctor has asked for one.

People taking Ramistar M XL are often asked to check these from time to time. Your doctor decides which and how often.

Manufacturer and class

Manufacturer:
LUPIN LAB
Therapeutic class:
Anti-hypertensive
Drug class:
Beta blocker and Angiotensin receptor blocker / ACE inhibitor

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Ramistar M XL 25 FAQs

What is Ramistar M XL 25 used for?
Ramistar M XL 25 is commonly used for high blood pressure, angina, heart failure, irregular heartbeat and diabetic kidney disease. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Ramistar M XL 25?
High blood pressure: Ramistar M XL slows the heart a little and lets it beat with less force, bringing blood pressure down and reducing the long-term risk of stroke and heart attack. It is also used for angina, heart failure, irregular heartbeat.
What is the salt in Ramistar M XL 25?
Ramistar M XL 25 contains Metoprolol + Ramipril. If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Ramistar M XL 25?
Use this medicine as your doctor has directed. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Ramistar M XL 25 work?
This medicine combines 2 active ingredients: Metoprolol and Ramipril.
Is Ramistar M XL 25 a prescription medicine?
Yes. Ramistar M XL 25 is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Ramistar M XL 25?
The side effects reported most often with Ramistar M XL are Tiredness, Cold hands and feet, Slow pulse, Dizziness, Disturbed sleep. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Ramistar M XL 25 be taken during pregnancy?
Ramistar M XL 25 is not recommended in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Ramistar M XL.
Can I drink alcohol while taking Ramistar M XL 25?
Limit alcohol while taking Ramistar M XL 25; it can worsen the side effects.
What if I miss a dose of Ramistar M XL 25?
Take it as soon as you remember.
Is Ramistar M XL 25 habit forming?
No. Ramistar M XL 25 is not known to be habit forming when taken as prescribed.
How much does Ramistar M XL 25 cost on PingMeDoc Pharmacy?
Ramistar M XL 25 starts at ₹219 (MRP ₹230) on PingMeDoc Pharmacy. Available in NA 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Ramistar M XL 25?
Ramistar M XL 25 is manufactured by LUPIN LAB. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Ramistar M XL 25 delivered?
Ramistar M XL 25 is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Ramistar M XL 25, Quick facts

Salt
Metoprolol + Ramipril
Best price
₹219
MRP
₹230
Prescription
Required (Rx)
Brand
LUPIN LAB
Manufacturer
LUPIN LAB
Therapeutic class
Anti-hypertensive
Drug class
Beta blocker and Angiotensin receptor blocker / ACE inhibitor
Habit forming
No
Variants
NA 10`S
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Ramistar M XL 25.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.