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Prescription requiredJB ChemicalsAntiglaucoma (IOP-lowering ophthalmic)

Simbrinza Drops

Brinzolamide 1% w/v + Brimonidine tartrate 0.2% w/v ophthalmic suspension

₹732In stock
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Delivered across India. ₹49 delivery, free above ₹999.

This medicine needs a prescription.

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Simbrinza Drops is used for treatment of elevated intraocular pressure (IOP) in open-angle glaucoma and ocular hypertension.

  • Original brandsFrom authorised distributors or the brand's own supply chain.

  • The price on the packYou pay the printed MRP. No inflated MRPs, no fake strike-throughs.

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  • 7 days to report a problemReport a wrong or damaged item within 7 days of delivery and our team reviews a return.

Key details

Salt: Brinzolamide 1% w/v + Brimonidine tartrate 0.2% w/v ophthalmic suspension
Available variants: drop 1%w/v + 0.2%w/v 5ML
Price: ₹732 (₹146.37 per ml)
Prescription: Required
Manufacturer: JB CHEMICALS

Ordering notes

Orders placed before 2 pm ship the same day, later ones the next day, every day of the week. Chennai: next-day delivery by Porter, ₹99 (free above ₹1,499). Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Simbrinza Drops

Simbrinza Drops contains Brinzolamide 1% w/v + Brimonidine tartrate 0.2% w/v ophthalmic suspension. It belongs to the Carbonic anhydrase inhibitor + Alpha-2 adrenergic agonist class of medicines.

Uses of Simbrinza Drops

  • Elevated intraocular pressure (IOP) in open-angle glaucoma
  • Ocular hypertension

Benefits of Simbrinza Drops

In Eye infection
Simbrinza clears the bacteria causing a red, sticky, painful eye, so the discharge, grittiness and redness settle within days.
In Eye inflammation
Simbrinza calms inflammation inside or on the surface of the eye, relieving redness, pain and sensitivity to light.
In Dry eyes
Simbrinza lubricates the surface of the eye, relieving the gritty, burning, tired feeling of dry eyes, especially after screen use or in air-conditioning.
In Glaucoma
Simbrinza lowers the pressure inside the eye, which is what protects the optic nerve from the slow, painless damage glaucoma causes to sight.
In Allergic conjunctivitis
Simbrinza relieves the itching, watering and redness of an allergic eye, so you can stop rubbing and the eye can settle.

How Simbrinza Drops works

Brinzolamide is a carbonic anhydrase inhibitor that reduces aqueous humour production in the eye, lowering intraocular pressure. Brimonidine is an alpha-2 adrenergic agonist that decreases aqueous humour formation and increases uveoscleral outflow, further reducing IOP.

How to take Simbrinza Drops

For ophthalmic use only. Instill 1 drop into the affected eye(s) as prescribed (commonly twice daily). Shake well before use. Remove contact lenses before instillation; reinsert after 15 minutes. If using other eye medicines, keep a 5–10 minute gap.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine is unlikely from eye use; flush the eye with clean water if too much is instilled. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Simbrinza Drops

Most side effects of Simbrinza are mild and settle as the body gets used to the medicine. The ones reported most often are:

  • Eye irritation/burning
  • blurred vision
  • dry eye
  • eye redness
  • foreign body sensation
  • bitter/abnormal taste
  • dry mouth
  • headache
  • fatigue/drowsiness

Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Simbrinza Drops

AlcoholCAUTION
Use with caution (may increase drowsiness/dizziness)
PregnancyCONSULT YOUR DOCTOR
Consult your doctor before using this in pregnancy.
Breast feedingCONSULT YOUR DOCTOR
Consult your doctor before using this while breastfeeding.
DrivingCAUTION
May cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneySAFE
No dose change is usually needed in kidney disease.
LiverSAFE
No dose change is usually needed in liver disease.

Warnings and precautions

Do not use if allergic to brinzolamide/brimonidine or sulfonamides. Use caution in severe kidney impairment (brinzolamide is contraindicated in severe renal impairment) and in patients with cardiovascular disease, orthostatic hypotension, depression, Raynaud’s phenomenon, or cerebrovascular insufficiency (brimonidine may worsen). May cause drowsiness/blurred vision—avoid driving until clear. Avoid touching dropper tip to prevent contamination. Use in children only if prescribed. Tell your doctor if you have dry eye/corneal problems.

Do not take Simbrinza if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for anyone with a known allergy to the preservative in the preparation.

Interactions with other medicines

MAO inhibitors, tricyclic antidepressants (may affect brimonidine), CNS depressants/alcohol (additive sedation), antihypertensives/cardiac glycosides (additive blood pressure/heart rate effects), other carbonic anhydrase inhibitors (e.g., acetazolamide) may increase systemic effects, other glaucoma eye drops (additive IOP-lowering)

How to store Simbrinza Drops

Store below 25°C. Protect from light and moisture. Do not freeze. Keep bottle tightly closed. Discard as per label/within recommended period after opening.

Quick tips for Simbrinza Drops

  • Press gently on the inner corner of the eye for a minute after instilling.
  • This keeps the drop in the eye and reduces the bitter taste.
  • Leave five minutes between two different drops.
  • Never share eye drops with anyone.

Manufacturer and class

Manufacturer:
JB CHEMICALS
Therapeutic class:
Antiglaucoma (IOP-lowering ophthalmic)
Drug class:
Carbonic anhydrase inhibitor + Alpha-2 adrenergic agonist

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Simbrinza Drops FAQs

What is Simbrinza Drops used for?
Simbrinza Drops is commonly used for Treatment of elevated intraocular pressure (IOP) in open-angle glaucoma and ocular hypertension. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Simbrinza Drops?
Eye infection: Simbrinza clears the bacteria causing a red, sticky, painful eye, so the discharge, grittiness and redness settle within days. It is also used for eye inflammation, dry eyes, glaucoma.
What is the salt in Simbrinza Drops?
Simbrinza Drops contains Brinzolamide 1% w/v + Brimonidine tartrate 0.2% w/v ophthalmic suspension. If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Simbrinza Drops?
For ophthalmic use only. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Simbrinza Drops work?
Brinzolamide is a carbonic anhydrase inhibitor that reduces aqueous humour production in the eye, lowering intraocular pressure.
Is Simbrinza Drops a prescription medicine?
Yes. Simbrinza Drops is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Simbrinza Drops?
The side effects reported most often with Simbrinza are Eye irritation/burning, blurred vision, dry eye, eye redness, foreign body sensation. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Simbrinza Drops be taken during pregnancy?
Consult your doctor before taking Simbrinza Drops in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Simbrinza.
Can I drink alcohol while taking Simbrinza Drops?
Limit alcohol while taking Simbrinza Drops; it can worsen the side effects.
What if I miss a dose of Simbrinza Drops?
Take it as soon as you remember.
Is Simbrinza Drops habit forming?
No. Simbrinza Drops is not known to be habit forming when taken as prescribed.
How much does Simbrinza Drops cost on PingMeDoc Pharmacy?
Simbrinza Drops starts at ₹732 on PingMeDoc Pharmacy. Available in drop 1%w/v + 0.2%w/v 5ML. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Simbrinza Drops?
Simbrinza Drops is manufactured by JB CHEMICALS. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Simbrinza Drops delivered?
Simbrinza Drops is delivered across India from our licensed pharmacy. Orders placed before 2 pm ship the same day, later ones the next day, every day of the week. Chennai: next-day delivery by Porter, ₹99 (free above ₹1,499). Enter your pincode on the page to see the date it reaches you.

Simbrinza Drops, Quick facts

Salt
Brinzolamide 1% w/v + Brimonidine tartrate 0.2% w/v ophthalmic suspension
Form
drop
Price
₹732 (₹146.37 per ml)
Prescription
Required (Rx)
Schedule
Schedule H
Brand
JB CHEMICALS
Manufacturer
JB CHEMICALS
Therapeutic class
Antiglaucoma (IOP-lowering ophthalmic)
Drug class
Carbonic anhydrase inhibitor + Alpha-2 adrenergic agonist
Habit forming
No
Variants
drop 1%w/v + 0.2%w/v 5ML
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.

  1. Manufacturer labeling/SmPC, established medical literature, standard ophthalmology references
  2. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  3. National List of Essential Medicines (NLEM) 2022, Government of India.
  4. Manufacturer's package insert / prescribing information for Simbrinza Drops.
  5. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.