Sitaglip M Tablet

Composition of Sitaglip M Tablet

Sitaglip M Tablet contains Sitagliptin + Metformin (strengths not specified). It belongs to the DPP-4 inhibitor + Biguanide class of medicines.

Uses of Sitaglip M Tablet

Treatment of type 2 diabetes mellitus to improve blood sugar control along with diet and exercise; used when metformin alone is insufficient or as combination therapy.

Key benefits

• Improves fasting and post-meal blood glucose control
• Helps improve insulin response in a glucose-dependent manner
• Reduces hepatic glucose production
• Lowers HbA1c when diet/exercise alone are insufficient
• Weight-neutral compared with some antidiabetics

How Sitaglip M Tablet works

Sitagliptin is a DPP-4 inhibitor that increases incretin hormones, leading to increased insulin release and decreased glucagon secretion in a glucose-dependent manner. Metformin decreases hepatic glucose production and improves insulin sensitivity, helping cells use glucose better.

How to take Sitaglip M Tablet

Tablet for oral use. Take exactly as prescribed by your doctor, usually with meals to reduce stomach upset. Swallow whole with water; do not crush/chew if it is an extended-release formulation (verify pack). Regularly monitor blood glucose/HbA1c.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine may cause low blood sugar, particularly if you also take other diabetes medicines. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Sitaglip M Tablet

Most side effects of Sitaglip M are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• headache
• upper respiratory tract infection
• sore throat
• hypoglycaemia (especially with insulin/sulfonylureas)
• flatulence

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Sitaglip M Tablet

Warnings and precautions

Type 2 diabetes only (not for type 1 diabetes or diabetic ketoacidosis). Metformin may rarely cause lactic acidosis—risk increases with kidney disease, severe dehydration, sepsis, heavy alcohol use, or hypoxia; kidney function should be checked before and during treatment. Sitagliptin has been associated rarely with pancreatitis and severe joint pain; seek medical help for severe abdominal pain. Use caution in renal impairment; dose adjustment/avoidance may be required depending on kidney function. Stop temporarily before iodinated contrast imaging and major surgery as advised by doctor.

Do not take Sitaglip M if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Alcohol (increases lactic acidosis risk), iodinated contrast media, carbonic anhydrase inhibitors (e.g., topiramate, acetazolamide), cimetidine, diuretics and ACE inhibitors/ARBs (may affect renal function), insulin and sulfonylureas (increased hypoglycaemia risk), digoxin (sitagliptin may increase levels)

How to store Sitaglip M Tablet

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep out of reach of children.

Expert advice for Sitaglip M Tablet

It can be taken with or without food, at the same time each day. Keep up your diet and activity — this medicine supports them. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.

Manufacturer and class

Manufacturer:

ANTHEM BIOPHARMA

Therapeutic class:

Antidiabetic

Drug class:

DPP-4 inhibitor + Biguanide