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Prescription requiredMsn LaboratoriesAnalgesic (opioid analgesic)

Tapal 50 Tablet

Tapentadol (50mg)

Available at our pharmacy counter

This medicine is dispensed in person against a valid prescription and is not sold online. Ask our pharmacist about availability, or speak to a registered doctor.

In-store reference price ₹254

Tapal 50 Tablet is used for moderate to severe acute pain requiring opioid analgesic treatment (e.g., musculoskeletal pain, postoperative pain) when other analgesics are inadequate.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Tapentadol (50mg)
Available variants: tablet 50mg 15`S
Best price: ₹254 (₹16.92 per tablet)
MRP: ₹267
Prescription: Required
Manufacturer: MSN LABORATORIES

Ordering notes

This medicine is dispensed in person at a licensed pharmacy counter and is not delivered.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Tapal 50 Tablet

Tapal 50 Tablet contains Tapentadol (50mg). It belongs to the Centrally acting opioid analgesic (μ-opioid receptor agonist + norepinephrine reuptake inhibitor) class of medicines.

Uses of Tapal 50 Tablet

  • Moderate to severe acute pain requiring opioid analgesic treatment (e.g.
  • musculoskeletal pain
  • postoperative pain) when other analgesics are inadequate.

Key benefits

  • Relieves moderate to severe pain
  • Dual mechanism for pain control
  • Useful when NSAIDs/weak analgesics are insufficient
  • Helps improve comfort and function during acute pain

How Tapal 50 Tablet works

Tapentadol is a centrally acting opioid analgesic. It works by dual mechanisms: μ-opioid receptor agonism and inhibition of noradrenaline reuptake in the CNS, reducing pain signal transmission and perception.

How to take Tapal 50 Tablet

Take exactly as prescribed by your doctor.

Side effects of Tapal 50 Tablet

Most side effects of Tapal are mild and settle as the body adjusts. Reported side effects include:

  • Nausea
  • vomiting
  • dizziness
  • drowsiness/somnolence
  • constipation
  • headache
  • dry mouth
  • fatigue

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Tapal 50 Tablet

PregnancyUse with caution / Consult doctor (avoid unless clearly needed; may cause neonatal withdrawal if used near delivery)
BreastfeedingBreast feeding CONSULT YOUR DOCTOR
AlcoholAvoid (can cause severe drowsiness and dangerous breathing problems)
DrivingDriving UNSAFE
KidneyKidney SAFE IF PRESCRIBED
LiverLiver CAUTION
Habit formingYes

Warnings and precautions

Prescription-only opioid; risk of dependence, abuse and withdrawal. May cause severe drowsiness, respiratory depression and low blood pressure—higher risk in elderly, debilitated, or with lung disease (asthma/COPD). Avoid combining with other CNS depressants. Use caution in head injury/raised intracranial pressure, seizure disorders, liver/kidney impairment. Do not stop abruptly after prolonged use. Not recommended in severe respiratory depression or paralytic ileus. Keep out of reach of children.

Do not take Tapal if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy.

Interactions with other medicines

Alcohol, benzodiazepines and other sedatives (additive CNS/respiratory depression), other opioids, antihistamines/sedating drugs, MAO inhibitors (avoid; risk of serious reactions), serotonergic drugs (SSRIs/SNRIs/TCAs/triptans/linezolid) may increase serotonin syndrome risk, strong CYP2D6/CYP3A4 modulators may alter exposure (clinical significance variable)

How to store Tapal 50 Tablet

Store below 25°C in a dry place, protected from light and moisture. Keep in original pack.

Expert advice for Tapal 50 Tablet

Tapal 50 Tablet is a strong painkiller which is used in the treatment of moderate to severe pain when other treatments do not treat your pain well enough or you cannot tolerate them. The addiction / habit-forming potential of Tapal 50 Tablet is very high. Take exactly as prescribed by your doctor. Use caution while driving or doing anything that requires concentration as Tapal 50 Tablet can cause dizziness and sleepiness. While taking this medication, avoid alcohol in all forms including beer, wine, aftershave lotions, mouthwash, vinegar, certain desserts, colognes, and liquid medications. Inform your doctor if you have asthma, liver, kidney or pancreatic disease, or are severely constipated.

Manufacturer and class

Manufacturer:
MSN LABORATORIES
Therapeutic class:
Analgesic (opioid analgesic)
Drug class:
Centrally acting opioid analgesic (μ-opioid receptor agonist + norepinephrine reuptake inhibitor)
Chemical class:
Phenylpropanes

Substitutes for Tapal 50 Tablet

Medicines with the same active ingredient (Tapentadol (50mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Tapal 50 Tablet
Vorth-Tp 50 mg TabletGLENMARK PHARMACEUTICALStablet · 10`S₹2675% more
Tapal ER 50 TabletMSN LABORATORIEStablet · 15`S₹30520% more
Hitap ER 50 mg TabletIntas Pharmaceuticals Ltdtablet · 15`S₹31725% more
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Tapal 50 Tablet FAQs

What is Tapal 50 Tablet used for?
Tapal 50 Tablet is commonly used for Moderate to severe acute pain requiring opioid analgesic treatment (e.g., musculoskeletal pain, postoperative pain) when other analgesics are inadequate. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Tapal 50 Tablet?
Tapal 50 Tablet contains Tapentadol (50mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How does Tapal 50 Tablet work?
Tapentadol is a centrally acting opioid analgesic.
Is Tapal 50 Tablet a prescription medicine?
Yes. Tapal 50 Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Tapal 50 Tablet?
The side effects reported most often with Tapal are Nausea, vomiting, dizziness, drowsiness/somnolence, constipation. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Tapal 50 Tablet be taken during pregnancy?
Use with caution / Consult doctor (avoid unless clearly needed; may cause neonatal withdrawal if used near delivery) Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Tapal.
Can I drink alcohol while taking Tapal 50 Tablet?
Avoid (can cause severe drowsiness and dangerous breathing problems)
Is Tapal 50 Tablet habit forming?
Yes Take Tapal only as directed and for the duration your doctor advises.
How much does Tapal 50 Tablet cost on PingMeDoc Pharmacy?
Tapal 50 Tablet starts at ₹254 (MRP ₹267) on PingMeDoc Pharmacy. Available in tablet 50mg 15`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Tapal 50 Tablet?
Tapal 50 Tablet is manufactured by MSN LABORATORIES. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Tapal 50 Tablet delivered?
Tapal 50 Tablet is a regulated medicine and is not delivered. It is dispensed in person at a licensed pharmacy counter against a valid prescription. Ask our pharmacist on WhatsApp about availability.

Tapal 50 Tablet, Quick facts

Salt
Tapentadol (50mg)
Form
tablet
Best price
₹254 (₹16.92 per tablet)
MRP
₹267
Prescription
Required (Rx)
Schedule
Schedule H1
Brand
MSN LABORATORIES
Manufacturer
MSN LABORATORIES
Therapeutic class
Analgesic (opioid analgesic)
Drug class
Centrally acting opioid analgesic (μ-opioid receptor agonist + norepinephrine reuptake inhibitor)
Chemical class
Phenylpropanes
Action class
μ-Opioid Receptor & Norepinephrine Reuptake Inhibitors (NRIs)
Habit forming
Yes
Variants
tablet 50mg 15`S
Delivery
Standard across India

References

The information on Tapal 50 Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Manufacturer labeling/pack insert, established medical literature (opioid analgesic pharmacology)
  2. Indian regulatory/market drug references
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Tapal 50 Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.