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Prescription requiredSystopic LabDermatological (Topical corticosteroid)

Topinate Cream

Clobetasol (0.05% w/w)

Topinate Cream is used for management of inflammatory and itchy skin conditions (steroid-responsive dermatoses) such as eczema/dermatitis and psoriasis (as prescribed).

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

₹82MRP ₹865% off₹2.72 per g
Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Clobetasol (0.05% w/w)
Available variants: cream 0.05%w/w 30GM
Best price: ₹82 (₹2.72 per g)
MRP: ₹86
Prescription: Required
Manufacturer: SYSTOPIC LAB

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Topinate Cream

Topinate Cream contains Clobetasol (0.05% w/w). It belongs to the Topical corticosteroid class of medicines.

Uses of Topinate Cream

Management of inflammatory and itchy skin conditions (steroid-responsive dermatoses) such as eczema/dermatitis and psoriasis (as prescribed).

Key benefits

  • Relieves itching
  • reduces redness and swelling
  • helps control flare-ups of eczema/dermatitis
  • improves inflammatory skin lesions

How Topinate Cream works

Topical corticosteroids reduce inflammation in the skin by suppressing release of inflammatory mediators. This decreases redness, swelling and itching.

How to take Topinate Cream

For external use only. Clean and dry the affected area, then apply a thin layer to the affected skin as directed by the doctor, usually 1–2 times daily. Avoid contact with eyes, mouth and broken skin; wash hands after application unless hands are treated.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Topinate Cream, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule.

If you take too much

An overdose of this medicine can suppress the body's own steroid production when it is used for a long time over large areas, especially in children. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Topinate Cream

Most side effects of Topinate are mild and settle as the body adjusts. Reported side effects include:

  • Burning or stinging
  • itching
  • dryness
  • redness
  • skin irritation
  • thinning of skin (with prolonged use)
  • acneiform eruptions

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Topinate Cream

PregnancyConsult doctor
BreastfeedingBreast feeding CONSULT YOUR DOCTOR
AlcoholNo known interaction
DrivingDriving
KidneyKidney
LiverLiver
Habit formingNo

Warnings and precautions

Use only on the affected area for the shortest duration advised. Do not use on face/groin/armpits unless prescribed; avoid occlusive dressings unless advised. Prolonged or excessive use can cause skin thinning, stretch marks or systemic steroid effects, especially in children. Do not use on untreated bacterial/fungal/viral skin infections; seek medical advice if symptoms worsen or infection develops.

Do not take Topinate if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for untreated bacterial, fungal or viral skin infections. Not for use in or around the eyes.

Interactions with other medicines

Other topical medicines on the same area (may increase irritation/absorption), occlusive dressings (increase absorption), potent topical steroids or systemic corticosteroids (additive effects)

How to store Topinate Cream

Store below 25°C in a cool, dry place. Protect from light and moisture. Keep cap tightly closed and out of reach of children.

Expert advice for Topinate Cream

Topinate Cream is used to treat redness, swelling, itching, and discomfort of various skin conditions. It should be applied to the affected areas as a thin film two or three times daily, or as advised by your doctor. Don't use it more often or for longer than advised by your doctor. Don't cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects. If you think the area of skin you are treating has become infected you should stop using Topinate Cream and consult your doctor. Consult your doctor if your skin condition has not improved after four weeks of treatment. Do not use it for more than 4 consecutive weeks at a time.

Manufacturer and class

Manufacturer:
SYSTOPIC LAB
Therapeutic class:
Dermatological (Topical corticosteroid)
Drug class:
Topical corticosteroid
Chemical class:
Gluco/mineralocorticoids, progestogin derivative

Substitutes for Topinate Cream

Medicines with the same active ingredient (Clobetasol (0.05% w/w)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Topinate Cream
Exel Skin CreamSun Pharmaceutical Industries Ltdcream · 30 Gm₹178118% more
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Topinate Cream FAQs

What is Topinate Cream used for?
Topinate Cream is commonly used for Management of inflammatory and itchy skin conditions (steroid-responsive dermatoses) such as eczema/dermatitis and psoriasis (as prescribed). Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Topinate Cream?
Topinate Cream contains Clobetasol (0.05% w/w). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Topinate Cream?
For external use only. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Topinate Cream work?
Topical corticosteroids reduce inflammation in the skin by suppressing release of inflammatory mediators.
Is Topinate Cream a prescription medicine?
Yes. Topinate Cream is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Topinate Cream?
The side effects reported most often with Topinate are Burning or stinging, itching, dryness, redness, skin irritation. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Topinate Cream be taken during pregnancy?
Consult doctor Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Topinate.
Can I drink alcohol while taking Topinate Cream?
No known interaction
What if I miss a dose of Topinate Cream?
If you miss a dose of Topinate Cream, apply it as soon as possible.
Is Topinate Cream habit forming?
No. Topinate Cream is not known to be habit forming when taken as prescribed.
How much does Topinate Cream cost on PingMeDoc Pharmacy?
Topinate Cream starts at ₹82 (MRP ₹86) on PingMeDoc Pharmacy. Available in cream 0.05%w/w 30GM. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Topinate Cream?
Topinate Cream is manufactured by SYSTOPIC LAB. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Topinate Cream delivered?
Topinate Cream is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Topinate Cream, Quick facts

Salt
Clobetasol (0.05% w/w)
Form
cream
Best price
₹82 (₹2.72 per g)
MRP
₹86
Prescription
Required (Rx)
Brand
SYSTOPIC LAB
Manufacturer
SYSTOPIC LAB
Therapeutic class
Dermatological (Topical corticosteroid)
Drug class
Topical corticosteroid
Chemical class
Gluco/mineralocorticoids, progestogin derivative
Action class
Glucocorticoids
Habit forming
No
Variants
cream 0.05%w/w 30GM
Delivery
Standard across India

References

The information on Topinate Cream is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Manufacturer labeling, established medical literature
  2. Indian pharmacology references
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Topinate Cream.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.